uriticara

Question 1

sever bought not repsonding to tx wht should you givein urticara

Answer 1

oral cotricosteriod with or withought non sedatign antih

Question 2

1st line tx uritcara

Answer 2

loratadine - non sedating antihistamine

Question 3

1st line for acne rosacea

Answer 3

top ivermectin

Question 4

how can we manage vitiligo - 4 things

Answer 4

sunblock for affected areas of skin
camouflage make-up
topical corticosteroids may reverse the changes if applied early
there may also be a role for topical tacrolimus and phototherapy, although caution needs to be exercised with light-skinned patient

Question 5

lanugo hair most commonly found in who - 2

Answer 5

newborn babies and malnutrition

Question 6

eczema herpeticum caused by what viruses

Answer 6

normally HSV sometimes cosackie

Question 7

antibodies target the desmosomes that connect the cells

Answer 7

pemphigus

Pemphigus is an autoimmune disease caused by antibodies directed against desmosomes. The antibodies target desmoglein 3, a cadherin-type epithelial cell adhesion molecule. Pemphigus presents in younger people and with flaccid, easily ruptured vesicles and bullae and mucosal ulceration.

Question 8

Antibodies to the basement membrane

Answer 8

pemphigoid

Question 9

The most common dermatosis in pregnancy is

Answer 9

atopic eruption of pregnancy

Question 10

chronic plaque psoriasis tx

Answer 10

Topical betamethasone applied once daily + topical calcipotriol applied once daily

Question 11

antiviral in hsingles prevent

Answer 11

Reduce the incidence of post-herpetic neuralgia

Question 12

drugs known to induce TEN

Answer 12

phenytoin
sulphonamides
allopurinol
penicillins
carbamazepine
NSAIDs

Question 13

what is TEN

Answer 13

Toxic epidermal necrolysis (TEN) is a potentially life-threatening skin disorder that is most commonly seen secondary to a drug reaction.

scalded appearance over an extensive area.

Some authors consider TEN to be the severe end of a spectrum of skin disorders which includes erythema multiforme and Stevens-Johnson syndrome,

Features
systemically unwell e.g. pyrexia, tachycardic
positive Nikolsky’s sign: the epidermis separates with mild lateral pressure

Question 14

perioral dermatiis made worse by what drug

Answer 14

steriods

Question 15

clusters of papules surroudnign erythema around her mouth, with sparing of the lip margin -

Answer 15

perioral dermatitis

Question 16

1st line for scalp psoriasis

Answer 16

Scalp psoriasis - first-line treatment is topical potent corticosteroids

Question 17

A 72-year-old man presents with a large nodule on his face. It is friable. There is no regional lymphadenopathy. He is lost to follow up and re-attends several months later. On this occasion the lesion has been noted to resolve with scarring

Answer 17

Keratoacanthomas may reach a considerable size prior to sloughing off and scarring.

Question 18

A 22-year-old woman is troubled by intensely itchy crops of blisters on her arms and legs. On examination she is malnourished and she has papulovesicular eruptions over her elbows and knees.

Answer 18

Dermatitis herpetiformis

Question 19

A 30-year-old man cuts the corner of his lip whilst shaving. Over the next few days a large purplish lesion appears at the site which bleeds on contact.

Answer 19

pyogenic granuloma

Question 20

how do you differentiate spider navi from telangiectasia

Answer 20

by pressing on them and watching them fill. Spider naevi fill from the centre, telangiectasia from the edge

spider navi - liver failure

Question 21

most common malignancy secodnary to immunosuppresion - renal trnasplant pt

Answer 21

scc of skin