Vaccines

Question 1

6 Diseases Give Preformed Abs For (5 after exposure, 1 prophylactic, and which 2 give combined passive and active immunization after exposure)

Answer 1

After exposure: To Be Healed Very Rapidly: Tetanus toxin, Botulinum toxin, HBV, Varicella, Rabies virus
RSV in newborns during winter prophylactically
Combined passive and active for HBV and Rabies

Question 2

Difference in Responses for Live Attenuated vs. Inactivated/Killed

Answer 2

Former generally stronger/lifelong whereas second weaker and needs boosters.
Cellular and humoral responses vs. just humoral

Question 3

Thymus Dependent vs. Independent Ags

Answer 3

Independent lacks polypeptide sequence so can’t be presented on MHC and stim Ts/induce memory (like LPS), so killed viruses require thymus-dependent (does have polypep)

Question 4

5 Live Attenuated Vaccines

Answer 4

MMR
Polio (Sabin, oral)
Influenza (intranasal)
Varicella
Yellow Fever

Question 5

4 Inactivated/Killed Vaccines

Answer 5

RIP Always
Rabies
Influenza (injection)
Polio (Salk, injected)
HAV

Question 6

2/3 Egg Based Vaccines

Answer 6

Flu and yellow fever so need skin test if have egg allergy. MMR has small component, but don’t need to worry about

Question 7

Live Vaccines and HIV

Answer 7

Don’t give to IC patients or close contacts. Except MMR.