Vasculitis Flashcards
What are RF for TAO?
male
smoking
What are features of the chronic phase of TAO?
organization of occlusive thrombus with recanalization
perivascular fibrosis
What are features of the intermediate/subacute phase phase of TAO?
partial recanalizations
disappearance of microabcess
deposition of immunoglobulins
What are features of the acute phase of TAO?
panvasculitis of small and medium vessels
occlusive, highly cellular arterial thrombus with microabcess
What are diagnostic criteria for TAO (shinoya criteria)?
smoking history/cocaine use
onset before 50
infrapop occlusive disease
upper limb involvement or phlebitis migranc
absence of other atherosclerotic RF
What are angiographic features of TAO?
Segmental occlusive lesions
more severe disease distally involvement of digital arteries,
normal proximal arteries without evidence of atherosclerosis
collateralization around areas of occlusion with corkscrew-shaped collaterals (Martorell’s sign, also described as “tree root” or “spider leg” collaterals)
What are angiographic features of TAO?
Segmental occlusive lesions
more severe disease distally involvement of digital arteries,
normal proximal arteries without evidence of atherosclerosis
collateralization around areas of occlusion with corkscrew-shaped collaterals (Martorell’s sign, also described as “tree root” or “spider leg” collaterals)
What are life style changes for TAO?
smoking cessation
exercise training
foot care
What are medical treatments for TAO?
ABX and NSAIDS for superficial phlebitis
CCB for vasospams
regional sympathetic block
statin
cilostazol
What are medical treatments for TAO?
ABX and NSAIDS for superficial phlebitis
CCB for vasospams
regional sympathetic block
statin
cilostazol
What are therapeutic options for TAO?
PCA
debride
flaps
amp
