Vasculitis Flashcards
1
Q
Giant Cell
A
- Large vessel
- granulomatous
- females >50
- headache, jaw claudification, double vision
- steroids ASAP (prevent blindness)
- very high ESR
- transmural, skipping lesions like PAN
- only lymphocytic commonly
2
Q
Takayasu arteritis
A
- large vessel
- granulomatous
- young asian women
- pulseless disease
- very elevated creatinine
- multiple aneurysms
3
Q
Polyarteritis nodosa
A
- medium vessel
- no glomerulonephritis, NO LUNGS
- all stages of inflammation
- no granulomas
- favors branch points of arteries
- males
- hep B
- beads on string (microaneurisms and fibrinoid necrosis)
- foot drop + acute abdomen
4
Q
Kawasaki’s Disease
A
- medium-small vessel
- asian boys
- coronary arteries
- aneurysms are common
- treat with aspirin
- strawberry tongue and rash
5
Q
Wegener’s Granulomatosis
A
- medium-small
- lung and glomerulonephritis
- c-ANCA
- ELK = ENT, Lung, Kidney
- saddle nose
- forms granulomas
6
Q
Churg Strauss
A
- small vessels
- granulomatous
- asthma and eosinophilia
- pANCA
- GU involvement
7
Q
Microscopic Polyangiitis
A
- small vessel
- glomerulonephritis and lung
- at same stage of disease
- pANCA
- no granulomas
8
Q
Henoch Schonlein Purpura
A
- small vessel
- IgA
- skin, gut, glomeruli, joints
- young males
9
Q
Essential cryoglobulinemia
A
- small vessel
- Hep C association
10
Q
Cutaneous Leukocytofclastic Angiitis
A
- small vessel
- no systemic vasculitis or glomerulonephritis
- skin disease without systemic issues
11
Q
Vasculitis from ICs
A
PAN
hypersensitivity vasculitis
HSP (IgA)
Essential Mixed Cryoglobulinemia
12
Q
Vasculitis from ANCA
A
Wegerner’s (only cANCA)
Microscopic polyangitis
Churg-strauss
13
Q
Cause glomerulonephritis
A
- all ANCA mediated
- IgA IC mediated
14
Q
Granulomas
A
All large vessels
All ANCAs except microscopic polyangiitis
15
Q
Veins affected
A
- Wegener’s
- HSP
- Churg Strauss
- Bachet’s disease
