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Microbiology > Virology > Flashcards

Virology Flashcards

0
Q

All helical viruses are

All icosahedral virus are

A

Enveloped

Naked

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1
Q

Nucleic acid genome

+ protein coat with repeating isomers

A

Nucleocapsid

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2
Q

All enveloped viruses acquire their envelope from plasma membrane except

A

Herpes virus

Nuclear membrane

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3
Q

T or F

Naked viruses are less stable and more easily inactivated

A

Enveloped

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4
Q

Naked RNA viruses

A

Calici
Picorna
Reo

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5
Q

Naked DNA viruses

A

Parvo
Adeno
Papilloma
Polyoma

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6
Q

Purified nucleic acids of
+ strand genome ssRNA viruses
dsDNA viruses EXCEPT
are infectious

A

Poxviruses

HBV

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7
Q

All viruses are haploid except

A

Retroviruses

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8
Q

Some RNA viruses have a SEGMENTED GENOME making them prone to

A

Genomic reassortment
Epidemics
Influenza

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9
Q

Segmented genome

A

Bunya
Orthomyxo influenza
Arena
Reo rotavirus

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10
Q

Negative strand RNA viruses must transcribe strand to positive so they bring their own

A

RNA dependent RNA polymerase

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11
Q

Negative Strand Viruses

A 
Always Bring Polymerase Or Fail Replication
Arena
Bunya
Paramyxo measles parainfluenza RSV
Orthomyxo influenza
Filo
Rhabdo rabies
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12
Q

One virus produces a protein that can be used by another virus

A

Complementation

Hep B and D

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13
Q

Two different viruses infect the same cell

A

Phenotypic mixing

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14
Q

Viral Growth Curve Phases

A 
0 entry
1 decline
2 eclipse no detection
3 rise
4 latent plateu
5 cytopathic viral amplification and cell function derangement
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15
Q

Outcomes of viral infection

A

Cytopathic effect visual or functional change
Malignant transformation
Commensal symbiosis numerous progeny

16
Q

Virulence factors

A

Cytokine decoys
Virokines APC and complement
Antigenic variants

17
Q

Persistent Viral Infection

A

Carrier state hep B and C
Latent infections varicella
Slow virus infections rabies

18
Q

Gold standard in viral diagnosis

A

Viral DNA or RNA

19
Q

Visual or functional change in infected cells

A

Cytopathic effect

Virulence factors

20
Q

Attachment of RBCs to surface of infected cells

A

Hemadsorption

Presumptive Identification

21
Q

Only live attenuated vaccine that may be given to HIV positive patients

A

MMR

22
Q

Vaccine that induces humoral and cell mediated immunity

A

Live attenuated vaccines

23
Q

Vaccine that induces humoral immunity only

A

Killed Vaccines

24
Q

Vaccines that may revert to virulence

A

Live attenuated vaccines

25
Q

Only live attenuated BACTERIAL vaccine

A

BCG

26
Q

Killed vaccines

A 
RIP Always
Rabies
Influenza
Polio (salk's)
Hep A
27
Q

Recombinant vaccines

A

Hep B

HPV 6 11 16 18

Microbiology (5 decks)

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