Viruses & Prions

Question 1

Normal Prion Protein

Answer 1

PrP^C

Question 2

Infectious Prion Protein

Answer 2

PrP^Sc

Question 3

How are Prions transmitted?

Answer 3

Only by close direct contact with infected tissues and secretions

Question 4

What is a virus particle composed of?

Answer 4

A nucleic acid core ( DNA or RNA, not both)

Question 5

What is a capsid composed of?

Answer 5

Protein subunits called capsomers

Question 6

What is acute non-persistent viral infection?

Answer 6

Happens quickly and comes & goes. Ex: common cold or influenza

Question 7

What is a latent persistent viral infection?

Answer 7

They stay dorment & then pop up. Ex: shingles or herpes

Question 8

What is a chronic persistent viral infection?

Answer 8

Last awhile. Ex: HIV, HPV, or Hepatitis C

Question 9

Steps of the Lytic Cycle

Answer 9

1. Adsorption
2. Penetraction
3. Synthesis
4. Assembly
5. Release

Question 10

Steps of dsDNA virus

Answer 10

1. Viral DNA enters nucleus
2. Transcription occurs
3. Translation
4. Replication
5. Assembly
6. Integration

Question 11

Steps of ssRNA+

Answer 11

1. Viral RNA enters cytoplasm
2. Translation
3. ssRNA+ serves as a template to make ssRNA-
4. ssRNA- makes more ssRNA+
5. Assembly

Question 12

Steps of Lysogenic Cycle

Answer 12

1. Adsorption
2. Penetration
3. Integration
4. Induction
5. Synthesis
6. Assembly
7. Release