Vit A and D Flashcards
Vitamin A
RDI Men / Women
2 forms
RDI: M1000/W800 Women Prego or planning NOT to exceed 2500 RE/day risk of birth defects
2 Forms: Retinol (in animals)
Carotenoids (in plants)
VIT A
Examples of Retinol (animal)
Carotenoid (plant)
Retinol Carotenoid
Beef Liver. Carrot
Cod Liver Oil Sweet Potato
Egg Spinach
Butter Apricots
Functions VIT A
Vision
Immune System
Skin & Mucous Membranes
Vision - plays a central role in retina conv of light energy into N impulse
Immune - improves antibody prod increases activity of Tcells & natural killers cells
Skin & Mucous Membranes - promotes healthy epithelial growth
VIT A Functions Hormone Synthesis RBC Nervous Skeletal
Hormone Syn: REQD for Steroid Hormone Synthesis
(Corticosteroids/Androgens & Estrogens)
RBC: assists to mobilize Fe stores in the prod of new RBC
Nerve: MAINTAIN MYELIN SHEATH around N.
Skeletal: helps w bone formation, growth and fx healing
VIT A DEFICIENCIES
- Dryness & Itching of Conjunctiva
- Poor night or low light vision (Xerophthalmia)
- Dry Rough itchy skin w rash
- Dry Brittle hair and nails
- Loss of appetite sense of smell/taste
- Fatigue Anemia poor growth
VIT A Retinol TOXICITY
- Bone Pain and Swelling
- Nausea Vomiting and Diarrhea
- H/As Blurred vision
- Dermatitis Hair Loss Dry Skin
- Liver Damage HIGH Blood Calcium
INCREASED DEF RISK VIT A
Decreased Absorption *alcoholics/liver-biliary disorders/ Chrons/Cystic Fibrosis
Poor Beta-Carotene conv to VitA *diabetics and hypothyroid
Increased Utilization - smokers, increased Stress, Diabetes, Infections, Sx
VIT A shown to help?
Major role in wound and bony fx healing Cancer prevention effects Improved Immune function Menstrual Pain Modification Skin and Scalp conditions Gastric Ulcer healing improvement
VIT D (CHOLECALCIFEROL)
RDI M/W
Dietary Source
LARGE DOSES are contraindicated for Pregnant due to potential Teratogenic effects M & W 5-15 mcg Salmon Egg Fortified Milk Butter Tuna
VIT D Functions Calcium Metabolism Skeletal Health Cell Growth Immune Function
Calcium Metabolism - regulation of blood calcium levels
Skeletal Health - Bone growth during childhood, strength and density during adulthood
Cell Growth - Regulator of cell dvlpmnt whole body (esp epithelial cells)
Immune Fxn - Cell dvlpmnt activity & response of WBC
VIT D Deficiencies
Rickets (children), Osteomalacia (adults)
Poorly Formed tooth enamel (child)
Increased risk of osetoporosis and fractures
Impaired immune response
Muscle weakness ESP hip&pelvis
VIT D TOXICITY
> 100-1000mcg/day
Hypercalcemia
Calcium Deposits into soft tissues
Renal Calcification - potential kidney stones
Increased Def of VIT D risk assoc w?
Lack of sun. (Confined/premature infants/reg use of sunscreen)
Persons w Fat Malabsorption syndromes, long term corticosteroid medication use
Strict vegetarians, elderly, diabetes, kidney dx
How can VIT D HELP?
Bone Disorders: treatment for rickets, along w calcium can slow/prevent bone loss
Psoriasis: can reduce hyperproliferation of skin cells (due to regulatory effect)
Immune Response: stimulate WBC and increase resistance to infection
Cancer prevention: may reduce risk of colorectal and breast CA