VSD Flashcards
CPB Normorthermic Blood Flow
0-3 kg = 200 cc/kg/min 3-10 kg= 150 cc/kg/min 10-15 kg= 125 cc/kg/min 15-30 kg= 100 cc/kg/min >30 kg= 75 cc/kg/min >55 kg= 65 cc/kg/min
At what day does cardiac septation occur?
Day 27
How long does cardiac septation last?
10 days
When do the formation of cardiac septa occur?
Simultaneously
During cardiac septation, how does the external appearance change?
No major changes in external appearance
What could cause worsening of a left-to-right-shunt?
Any process that increases the pressure in the LV can cause worsening of the left-to-right shunt; also works on the right heart Systemic hypertension, increases pressure that the LV has to generate in order to open the aortic valve
What could cause worsening of a left-to-right-shunt?
Any process that increases the pressure in the LV can cause worsening of the left-to-right shunt; also works on the right heart Systemic hypertension, increases pressure that the LV has to generate in order to open the aortic valve
If there is a L to R shunt, which ventricle has to push our more blood? What does this result in?
Right ventricle; constant overload of the right side of the heart will cause an overload of the entire pulmonary vasculature (pulmonary over-circulation)
If there is a L to R shunt, which ventricle has to push our more blood? What does this result in?
Right ventricle; constant overload of the right side of the heart will cause an overload of the entire pulmonary vasculature (pulmonary over-circulation)
Qp/Qs > 1.5/1.0
Problem!! Eventually pulmonary hyptertension will develop
What does pulmonary hyptension cause for the RV?
Increased afterload (PVR) In addition to increased preload that the shunted blood form the LA to RA caused RV will be forced to generate higher tension/pressures to try to overcome the pulmonary HTN Could lead to RV failure (dilatation and decreased systolic function of the RV)
If Left to Right shunt is left uncorrected….
Pressure in right heart> pressure in left heart RA pressure > LA pressure Pressure gradient reverses across the ASD Shunt reverses (R to L shunt)= Eisenmenger’s syndrome Oxygen-poor blood gets shunted to the left heart Cyanosis
Eisenmenger’s Syndrome
Reversal of a L to R shunt to become a R to L shunt Oxygen-poor blood gets shunted to the left heart Causes cyanosis
Surgical Closure of VSD: Cardioplegia
Antegrade; usually a single dose will suffice
Surgical Closure of VSD: Case Notes
Very, very quick (5-10 min pump run) Will XC, Stay warm “ drift down temp “ Can be challenging: (on CPB, XC, CPG, warm, correct Ca++, lytes, ABG’s off CPB-MUF)
VSD
defect in the ventricular septum, the wall dividing the left and right ventricles of the heart
What does the ventricular septum consist of?
Inferior muscular portion Superior membranous portion
Common Regions of VSDs
Inlet Outlet (supracristal) Peri-membranous septum Muscular septum
What is the #1 type of VSD we will see? (What percent)
Per-membranous septum (75%)
What percent of VSDs are muscular?
20%
What percent of VSDs are supracristal (outflow)?
5%
Muscular VSDs are found in what four locations?
Anterior Mid-ventricular Posterior Apical