Week 1 Flashcards
Kandel quiz
How do we define learning vs memory
Acquistion of information vs storage and recall
What technique, developed in the 90’s allowed us to see the human brain alive.
Functional Magnetic Resonance Imagine (MRI)
What was the major difference in the surgery performed on HM in 1953 compared to previous surgeries carried out by Wilder Penfield?
It was bilateral- previous surgeries had only even been unilateral.
Where in the brain is the short term working memrory buffer believed to be?
Prefrontal cortex
What were Brenda Milner’s 2 main findings about HM
HM cannot form new conscious (declarative) memories, but he can learn motor skills (procedural). Showing that there is an anatomical distiction between declerative and procedural memory.
Brenda Milner’s studies of HM lead to the definitions of which types of memory
Explicit vs Implicit
What maked Aplysio Californica a useful model system for studying learning and memory.
A simple nervous system arranged into ganglia with large nerve cells, but generates a range of behaviours.
What 4 types of learning can Aplysia display?
Sensitisation, habituation, classical conditioning, and operant conditioning.
Is protein synthesis necessary for memory?
Yes for long term, no for short term.
Whats the neuromodulator involved in Aplysia gill withdrawl
Serotonin
What happens with cAMO after multiple stimuli leading to LTM vs signle stimulus leading to STM (ie, where does it additionally relocate)
Nucleus
What neurotransmitter/ modulator in the hippocampus is the mammalian equivelant of serotonin in the aplysia?
Dopamine
What is the timescale of early vs late LTP
Early up to 90 mins, late up to days (even weeks/months)
Which type of memory involved the POST-synaptic cell
Explicit
