Week 1 trial

Question 1

Pharmacokinetics -

Answer 1

what the body does to the drug

Question 2

Absorption:

Answer 2

The movement of a drug from its site of administration into the blood

Question 3

Distribution:

Answer 3

The movement of drugs throughout the body

Question 4

Metabolism:

Answer 4

Transformation of a drug by enzymes into metabolites

Question 5

Excretion:

Answer 5

Drug removal from the body

Question 6

Pharmacodynamics -

Answer 6

what the drug does to the body; Study of the relationship between the drug and a target cell or receptor to produce a therapeutic effect in a patient

Question 7

Pharmacogenomics -

Answer 7

study of the genetic attributes of an individual that lead to variable responses to drugs

Question 8

Pharmacoeconomics -

Answer 8

Description and analysis of the cost of drug therapy to healthcare systems and society

Question 9

Drug:

Answer 9

any chemical that produces a measurable biological response

Question 10

Pharmacology:

Answer 10

the study of drugs and their actions

Question 11

Pharmacotherapeutics:

Answer 11

the use of drugs to diagnose, prevent, or treat disease or to prevent pregnancy

Question 12

Prodrugs:

Answer 12

Inactive compounds that rely on metabolism to become active

Question 13

Bioavailability:

Answer 13

percentage of administered dose that enters the bloodstream

Question 14

Efficacy:

Answer 14

index of the maximal response a drug can produce regardless of dose

Question 15

Potency:

Answer 15

index of how much drug must be administered to elicit a desired response

Question 16

ED50 =

Answer 16

amount of drug that produces the desired effect in 50% of the people taking it

Question 17

LD50 =

Answer 17

amount of drug that produces toxicity in 50% of the people taking it

Question 18

Therapeutic index:

Answer 18

Ratio of LD50 to ED50; Drugs with narrow therapeutic index have a very narrow range between the dose that is effective and the dose that is toxic

Question 19

Genes:

Answer 19

a stretch of DNA which encodes for proteins and determines genetic characteristics.

Question 20

Genotype:

Answer 20

an individual’s genetic makeup derived from mixing of genes from that individual’s parents

Question 21

Phenotype:

Answer 21

physical characteristics of an individual based on expression of the genotype

Question 22

Common Supplements

Answer 22

o Calcium o Echinacea o Fish Oil o Ginseng o Glucosamine and/or Chondroitin Sulphate o Garlic o Vitamin D o St. John’s Wort o Saw Palmetto o Ginkgo o Green Tea