Week 2: Thorax Flashcards

1
Q

LO: Identify the features of true, false and floating ribs and their attachments to the vertebral column/ sternum

A
  • Bony thorax: 12 thoracic vertebrae, 12 rib pairs, sternum
  • Typical rib:
    o Costal groove runs along internal/ inferior border
    o Rib facets articulate with vertebrae: 2 articular facets separated by crest on head, 3rd tubercular facet on tubercle (facing down, articulates with facing up costal facet of transverse process of numerically corresponding vertebra –> costotransverse joint)
    o Crest articulates where intervertebral disc would be
    o Bone –> end anteriorly with hyaline cartilage tip = costal cartilage
  • True ribs (1-7): articulate directly with sternum via costal cartilage
  • False ribs (8-12): do not articulate directly with sternum;
    o Ribs 8-10 articulate anteriorly with costal cartilage of rib 7 – thus articulate indirectly with sternum
    o Floating ribs (11-12): no anterior articulation; cartilaginous tips end in thoracic wall musculature
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2
Q

LO: Describe the clinical significance of the sternal angle

A
  • sternal angle = Angle of Louis = manubriosternal joint
  • important clinical landmark from which measure height of JVP (located 3 fingers/ 4-5cm below jugular notch)
  • articular demifacets above/ below angle for rib II
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3
Q

LO: Enumerate the ribs and intercostal spaces

A
  • Intercostal spaces enumerated relative to rib above
  • 5th ICS MCL = heart apex
  • In life, ICSs closed by intercostal muscles joining adjacent ribs (move ribs to breathe; 3 layers from superficial to deep: external, internal, innermost) and contain lymphatics, veins, arteries, nerves (VAN = intercostal neurovascular bundles located between internal/ innermost intercostal muscles) supplying thoracic wall skin –> parietal pleura
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4
Q

LO: Identify the superior/ inferior thoracic apertures and the structures that pass through them

A
  • Superior thoracic aperture: aka thoracic outlet; formed by T1, 1st ribs, manubrium superior border
    o If viscera are to pass between thorax/ head/ neck/ upper limbs – MUST pass through this opening BUT rigid
    o Contains viscera: trachea, esophagus, R/L lung apices, great vessels (common carotid and subclavian arteries, internal jugular and subclavian veins), LVs draining head/ neck/ upper limbs, nerves
    ♣ If any become enlarged/ cervical rib –> compress others –> thoracic outlet syndrome (Sxs: pale/ swollen/ cold/ aching upper limb, weakness/ wasting muscles of hand, pain/ tingling upper limb)
  • Inferior thoracic aperture: formed by T12, 12th ribs, 11th ribs, costal margin, ziphisternal joint
    o Origin of diaphragm (muscular sheet almost completely closing opening) – structures passing between thorax/ abdomen must pass behind (aorta) OR through openings (esophagus, IVC)
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5
Q

Fascia

A
  • a connective tissue layer as observed with the naked eye (ie. at the gross level, rather than under a microscope)
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6
Q

Epi vs hypodermis

A
  • epi = above/ superficial to; the epidermis is superficial to the dermis
  • hypo = below/ deep to; the hypodermis is deep to the dermis of the skin
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7
Q

Costal groove

A
  • runs along inferior border of rib on its internal surface (so you can orient rib!)
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8
Q

Bony thorax

A
  • consists of 12 thoracic vertebrae, 12 pairs of ribs, sternum
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9
Q

True ribs

A
  • I-VII

- articulate directly with sternum via their costal cartilage

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10
Q

False ribs

A
  • VIII-XII
  • do not directly articulate with sternum
  • ribs VIII-X articulate anteriorly with costal cartilage of rib above, thus articulate indirectly with sternum
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11
Q

Costal margin

A
  • inferomedial border of ribcage, formed by connected cartilages of ribs VII-X and the xiphoid process
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12
Q

Floating ribs

A
  • XI-XII

- false ribs with no anterior articulation; cartilaginous tips end in musculature of thoracic body wall

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13
Q

Supernumerary rib

A
  • “Cervical rib”
  • Present in 1% population either uni/ bilaterally
  • Articulate with C7
  • May –> thoracic outlet syndrome
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14
Q

LO: Identify the features of the sternum

A

from superior to inferior:
- manubrium (handle); articulates with ribs I-II
o Manubrium has jugular/ suprasternal notch on top and articulates with clavicles/ rib 1/ rib2 at sternal angle (but cannot palpate manubrium/ rib articulations as clavicle covers)
- body; ribs II-VII
- xiphoid (sword-like) process; rib VII only

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15
Q

Eponym

A
  • name of a structure/ disease/ procedure derived from name of person who first described/ discovered it
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16
Q

Superior thoracic aperture

A
  • aperture = opening
  • aka thoracic outlet
  • formed by T1, ribs I, superior border of the manubrium
  • if viscera are to pass between the thorax and head/ neck/ upper limbs, must pass through this opening
  • composed of bone, thus rigid
  • contains trachea, esophagus, lung apices, great vessels (common carotid/ subclavian arteries, internal jugular/ subclavian veins), lymphatics draining head/ neck/ upper limbs, major nerves
  • thoracic outlet syndrome: if any of above structures become enlarged, will compress others due to rigidity of outlet; can also occur in patient with cervical rib
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17
Q

Inferior thoracic aperture

A
  • formed by T12, ribs XI-XII, costal margin, ziphisternal joint
  • origin of diaphragm (muscular sheet that almost closes opening)
  • structures that pass between thorax/ abdomen pass either behind diaphragm (aorta) OR through openings in diaphragm (esophagus, inferior vena cava)
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18
Q

LO: Describe the innervation of the thoracic wall

A
  • Thoracic body wall (all 5 layers) innervated by branches of dorsal/ ventral rami of thoracic spinal nerves T1-12 (contain somatic motor/ sensory, sympathetic postganglionic motor)
    o Dorsal rami extend posteriorly –> innervate paraxial region (back muscles/ skin)
    o Ventral rami continue between adjacent ribs as intercostal nerves; ventral ramus of T12 spinal nerve continues inferior to 12th rib as subcostal nerve
    o As sweep anteriorly/ inferiorly, T7-T11 and subcostal nerve innervate abdo wall
  • Rami communicantes: connections between sympathetic chain/ ventral ramus/ intercostal nerve
    o Convey sympathetic preganglionic fibres from SC cell bodies sympathetic chain ganglion –> sympathetic postganglionic fibres –> rami
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19
Q

LO: Identify the structures within the posterior/ superior mediastinum

A
  • Arteries
    o Aortic arch 3 main branches: brachiocephalic trunk (branches into right common carotid, right subclavian), left common carotid artery, left subclavian artery
    ♣ Subclavians supply shoulders/ upper limbs, common carotids supply head/ neck
  • Veins
    o Right venous angle: R IJV + R subclavian V –> R brachiocephalic V
    o Left venous angle: L IJV + L subclavian V –> L brachiocephalic V
    o R + L brachiocephalic veins –> SVC –> RA
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20
Q

LO: Describe/ identify the blood supply to/ from the thoracic wall

A
- Posterial arterial supply – Thoracic aorta:
o	Parietal (“of the walls”) branches of thoracic aorta = posterior intercostal arteries (supply thoracic wall)
o	Visceral branches of thoracic aorta supply esophagus, bronchial tree, pericardium
- Posterior venous supply – Posterior intercostal veins drain posterior thoracic body wall  --> azygous venous system --> SVC --> RA
o	R posterior intercostal veins --> azygous vein (arches OVER R bronchus) --> SVC
o	L posterior intercostal veins --> hemiazygous V (lower) OR accessory hemizygous V --> cross over midline into azygous V --> SVC
- Anterior arterial/ venous supply – Internal surface of chest plate: internal thoracic (mammary) arteries/ veins run vertically along lateral borders of sternum
o	R/ L subclavian arteries --> R/ L internal thoracic arteries --> anterior intercostal arteries --> arterial anastomoses with posterior intercostal arteries in thoracic wall along MCL
o	1+ internal thoracic vein accompanies each internal thoracic artery
♣	Anterior intercostal veins drain intercostal spaces --> internal thoracic veins --> drain superiorly --> brachiocephalic veins --> SVC
♣	Anterior/ posterior intercostal veins form venous anastomoses along MCL
- Summary:
o	Anterior/ posterior intercostal arteries arise from distinct arterial sources (internal thoracic arteries/ thoracic aorta)  form arterial anastomosis
o	Anterior/ posterior intercostal veins drain into distinct venous networks (internal thoracic veins/ azygous venous system) – form venous anastomosis
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21
Q

LO: Describe the lymphatic drainage of the body wall

A
  • Lymph = excess interstitial fluid
  • Blood plasma leaks out of capillaries –> interstitial fluid –> lymphatic capillaries as lymph with cells/ cell products/ pathogens –> lymph vessels –> lymph nodes (cleanse lymph of foreign/ transformed cancerous cells –> venous system
  • Lymphatic drainage of thoracic wall follows venous drainage
    o Lymph from chest wall drains posteriorly –> intercostal lymph nodes –> thoracic duct ON L SIDE –> L venous angle
    o Lymph drains anteriorly –> parasternal lymph nodes –> R/ L bronchomediastinal trunks –> R/ L venous angles
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22
Q

LO: Describe/ identify features of the autonomic innervation of the thoracic viscera

A
  • ANS (sympathetic/ parasympathetic) innervates smooth muscle, cardiac muscle, glands
    o Exception: muscle/ glands in body wall/ limbs ONLY controlled by sympathetic
  • Sympathetic output for all body targets arises from SC T1-L2 (ie. cell bodies of sympathetic PREganglionic neurons)
    o Sympathetic output for thoracic viscera ONLY from T1-T4 –> postganglionic neuron cell bodies in sympathetic chain ganglia
    o Rather than travelling back to spinal nerves as with body wall/ limbs, thoracic viscera postganglionic axons directly innervate viscera as sympathetic visceral nerves (ie. sympathetic cardiac nerves)
  • Parasympathetic output for most body targets arises from brainstem and travels with cranial nerves, remainder from SC S2-S4
    o Thoracic viscera receive parasympathetic PREganglionic input from cranial nerve X (vagus nerve)
    ♣ Vagus nerves descend from brainstem through neck and recurrent branches turn back/ ascend on either side of trachea to innervate larynx
    • R recurrent laryngeal nerve recurs around R subclavian artery
    • L recurrent laryngeal nerve recurs around aortic arch
  • Sympathetic/ parasympathetic inputs to viscera overlap in autonomic plexi (ie. cardiac/ pulmonary/ esophageal plexi)
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23
Q

Intercostal nerves

A
  • ventral rami of thoracic spinal nerves continue between adjacent ribs as intercostal nerves
  • T7-T11 intercostal (and subcostal) nerves sweep anteriorly/ inferiorly and innervate abdo wall
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24
Q

Subcostal nerve

A
  • the ventral ramus of the T12 spinal nerve continues inferior to the 12th rib as the subcostal nerve
  • subcostal (and T7-T11 intercostal) nerves sweep anteriorly/ inferiorly and innervate abdo wall
25
Q

Brachiocephalic

A
  • brachium = arm
  • cephalus = head
  • vessel that supplies arm/ head
26
Q

Subclavian

A
  • sub = inferior
  • clavian = clavicle
  • subclavian artery runs inferior to clavicle
27
Q

Right venous angle

A
  • R subclavian V (horizontal) joins R internal jugular V (vertical) to form R brachiocephalic V (diagonal)
28
Q

Left venous angle

A
  • L subclavian V (horizontal) joins L internal jugular V (vertical) to form L brachiocephalic V (diagonal)
29
Q

SVC

A
  • superior vena cava
  • formed by union of R & L brachiocephalic veins
  • returns venous blood to RA
30
Q

Intercostal muscles

A
  • function to move ribs to change volume of thorax during inspiration/ expiration
  • 3 layers (from superficial to deep): external, internal, innermost
31
Q

Intercostal neurovascular bundles

A
  • neurovascular bundles = group of nerves, blood/ lymphatic vessels that travel together to common targets
  • located between internal/ innermost intercostal muscles
  • branches supply tissues throughout thickness of thoracic wall (from skin to parietal pleura)
32
Q

Posterior intercostal vein/ artery, intercostal nerve

A
  • lateral to vertebral column, in order VAN (vein, artery, nerve) from superior to inferior
  • disappear behind innermost intercostal muscles as pass anteriorly
33
Q

Rami communicantes

A
  • connections between ventral ramus/ intercostal nerve and sympathetic chain
34
Q

Parietal branches of thoracic aorta

A

= posterior intercostal arteries

- supply thickness of chest wall

35
Q

Parietal

A

= “of the walls”

  • refers to walls that contain organ(s)
  • ie. thoracic walls contain thoracic viscera
36
Q

Visceral branches of thoracic aorta

A
  • supply esophagus, bronchial tree, pericardium
37
Q

Pericardium

A
  • peri = around/ surrounding; cardium = heart
38
Q

Azygous venous system

A
  • posterior intercostal veins drain the posterior thoracic body wall
39
Q

Anastomoses

A
  • communication between vessels

- tissues supplied by an arterial anastomosis receive blood from 2 sources

40
Q

Anterior intercostal veins

A
  • form venous anastomoses with posterior intercostal veins in thoracic wall at ~ the MCL
  • drain blood from intercostal spaces into internal thoracic veins, which then drain superiorly into brachiocephalic veins, which unite to form the SVC
41
Q

Thoracic duct

A
  • lymph from chest wall drains posteriorly into intercostal lymph nodes and from there –> thoracic duct
42
Q

Bronchomediastinal trunk

A
  • lymph from chest wall drains anteriorly into parasternal lymph nodes and from there –> bronchomediastinal trunk
43
Q

Layers of the thoracic wall

A

• Mediastinum: region between pleural cavities/ lungs

44
Q

Costal margin

A

o Inferomedial border of ribcage formed by connected cartilages of ribs 7-10 and xiphoid process

45
Q

Lymphatic drainage of breast

A

o 75% lymph draining from breast passes superolaterally through axillary/ supraclavicular nodes subclavian trunks
o Much of remaining drains medially parasternal nodes bronchomediastinal trunks
o Small portion drains inferiorly into abdominal/ superficial inguinal nodes
o Tumours spread by lymph/ venous blood/ direct invasion adjacent tissues
♣ Breast CA thus spread superiolaterally to axillary/ supraclavicular nodes, medially to parasternal, inferiorly to abdominal/ superficial inguinal nodes
♣ Lymph flowing medially to parasternal nodes can also cross midline from one breast to other

46
Q

Serous membrane

A

o Line body cavities and produce serous fluid (contained within cavity)
o Visceral pleura on lung, parietal pleura on inner chest wall

47
Q

Potential space

A

o Space that can develop under pathological conditions between 2 normally adjacent surfaces, separated only by small volume fluid

48
Q

Pleural effusion

A

o Fluid accumulates in lowest part of chest in response to gravity

49
Q

LO: Describe the pleural cavity

A

• Pleural cavities = potential spaces filled with capillary layer pleural fluid (produced by pleura = lubricant for lungs/ chest wall during breathing)

50
Q

LO: Identify features of the lungs

A

• 3 surfaces: costal surface (extensive curved surface adjacent ribs), mediastinal, diaphragmatic (aka base)
o Apex opposite base, extends above clavicle into thoracic inlet
• Hilum: region of mediastinal surface where root of lung (airways, VAN, LVs bound together by CT) enter/ leave lung

51
Q

LO: Describe the serous membranes/ pleura associated with lungs/ pleural cavity

A
  • Surfaces of parietal pleura: costal, mediastinal, diaphragmatic, cervical (lining cupola of pleural cavity, which houses apex)
  • Parietal/ visceral pleura continuous at root of lung
52
Q

LO: Describe diaphragm innervation by phrenic nerves

A
  • Diaphragm: domed shape thin muscular sheet separating thoracic/ abdominopelvic cavities
    o Originates from inferior thoracic aperture
    o Striated voluntary muscle fibres organized radially (like bicycle wheel spokes), insert into non-contractile central tendon – thus contraction –> dome flattens –> thoracic cavity increases
    o Somatic innervation by R/ L phrenic nerves (form from twigs from ventral rami of R/ L C3, C4, C5 spinal nerves), which descend from neck into thorax via thoracic inlet run laterally to mediastinum, deep to mediastinal parietal pleura, ANTERIOR to root of lung (“frenic in front”)
    ♣ Cell bodies of somatic motor neurons in SC C3, C4, C5 – axons form phrenic nerve
    o (vagus nerves descend from neck into thoracic inlet but pass POSTERIOR to root of lung)
    o Sensory fibres from diaphragm, diaphragmatic pleura, mediastinal parietal pleura, pericardial sac –> C3, C4, C5
    o Phrenic nerve also contains sympathetic postganglionic fibres from cervical sympathetic chain ganglia to control vascular smooth muscle within its territory
53
Q

LO: Describe referred pain of diaphragm

A

• Pain signals conveyed along phrenic nerve (due to irritation of: diaphragm, diaphragmatic pleura, mediastinal pleura, pericardial sac or phrenic nerve itself somewhere along its course) conveyed to SC C3, C4, C5
o These SC levels also receive sensory afferents from C3-C5 dermatomes, which includes skin overlying shoulders
o Thus pain from diaphragm may be referred to shoulder

54
Q

LO: Describe mediastinum subdivisions

A

• Mediastinum: region between pleural cavities/ lungs; extends from superior thoracic aperture to inferior thoracic aperture/ from sternum to thoracic vertebrae; 4 subdivisions:
o Super mediastinum: from superior thoracic aperture to horizontal plane through sternal angle back between T4/T5 vertebrae (remainder 3 divisions below plane)
♣ Bulk of thymus located in superior mediastinum, posterior to manubrium (may extend inferiorly into anterior mediastinum)
• Thymus involved in immune development, particularly in children/ adolescents when largest –> atrophied in elderly
o Anterior: region between sternum/ pericardial sac
o Middle: pericardial sac/ cavity, heart
o Posterior: region between pericardial sac/ T5-T12 vertebrae

55
Q

LO: Identify fibrous/ serous pericardium of pericardial sac

A
  • Outside: fibrous pericardium defines middle mediastinum, composed of dense/ irregular CT, tough/ white/ inextensible sack
  • Inside: serous/ parietal pericardium
56
Q

LO: Describe pericardial cavity

A

• Parietal/ visceral serous pericardium continuous at base of great vessels, where also fibrous pericardium becomes continuous with tunica adventitia (outermost CT layer of great vessels)

57
Q

LO: Identify surfaces of heart

A
  • Covered by serous visceral pericardium
  • Rests on diaphragmatic surface, anterior surface faces sternum (RV), R pulmonary surface (RA), L pulmonary surface (LV), posterior base (LV, some RV)
58
Q

LO: Describe orientation of heart in situ

A
  • Apex pointed down, forward, left (thus R side faces anteriorly)
  • Base pointed posterior (opposite apex)