Week 9: Cardiovascular prac results Flashcards

1
Q

What was the mean for the blood pressure prac age like?

A

Asymmetrical, skewed towards younger ages

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2
Q

What was the distribution for height?

A

Normal distribution

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3
Q

What is the relationship between weight and BP?

A

Weight isn’t only determinant but association exists

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4
Q

What happens to blood pressure after standing for 2 minutes?

A

Drop of systolic, rise in diastolic

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5
Q

What happens to MAP and PP on standing?

A

MAP rises slightly, PP drops by about 10mmHg

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6
Q

What is the arterial pulse wave like for supine and standing?

A

Similar amplitude (mean pressure increased slightly)

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7
Q

Why does pulse pressure fall on standing?

A

Reduced venous return (gravity, blood polling in legs)

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8
Q

What is pulse pressure affected by?(4)

A

Compliance of large arteries, stroke volume, reflected waves, pooling of blood in lower limbs

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9
Q

What happens with reflected waves and aging?

A

Arteries stiffen, velocity of blood increases (unidirecitonally and reflected)

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10
Q

What happens immediately when going from supine to standing?

A

CO down, PP down

SNS activated, PSNS lessened

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11
Q

How is MAP maintained when going from supine to standing?

A

TPR maintains MAP (increases)

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12
Q

What was the effect of standing pre-treatment ? (SBP, DBP, MAP, HR, SV, CO, TPR)

A
SBP: Decrease
DBP: Increase
MAP: Same
HR: Increases
CO (SV): Decreases
TPR: Increases
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13
Q

What happened to the parameters after treatment when standing?

A

Same as pre treatment

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14
Q

What does caffeine do?

A

Increases BP mainly through TPR

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15
Q

What does nicotine do?

A

No effect on BP, no decrease in supine HR with time

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16
Q

Normally, what happens to HR/CO in a supine position?

A

They decrease with time

17
Q

What happens with a combination of caffein and nicotine?

A

Same as caffeine (increased BP) but HR decrease absent

18
Q

What effect do caffeine and nicotine have on the skills test?

A

Each improve ruler catch and increase tremor, but combination effect lost

19
Q

Are skeletal muscle and CV effects dependent?

A

No, independent

20
Q

What may caffeine’s BP response variation be due to?

A

Polymorphisms of adenosine A2A R’ and a2-adrenoceptor

21
Q

What type of drug is nicotine?

A

Nicotinic R’ agonist

22
Q

What type of drug is caffeine?

A

Adenosine receptor antagonist, phosphodiesterase inhibitor

23
Q

What do adenosine receptors initiate?

A

Vasodilation, decreased HR, increase in Ca in skeletal muscle