Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

MTM > Weeks 3-4 > Flashcards

Weeks 3-4 Flashcards

1
Q

Streptomycin, tetracycline

A

inhibit prokaryotic translation via the 30S subunit.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

Chloramphenicol, Erythromycin

A

inhibit prokaryotic translation via the 50S subunit.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

Puromycin

A

prematurely prevents prokaryotic translation by accepting peptide bond

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

Diphtheria toxin

A

inhibits eukaryotic translation via inhibition of eEF-2 (translocation).

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

Ricin

A

inhibits eukaryotic translation via inhibition of peptidyl transferase activity.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

Irinotecan, Topotecan

A

inhibit eukaryotic topoisomerase I

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

Doxorubicin, Etoposide

A

inhibit eukaryotic topoisomerase II

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

Ciprofloxacin

A

inhibits bacterial topoisomerase

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

RNAP I

A

transcribes rRNA in nucleoplasm.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

RNAP II

A

transcribes mRNA, miRNA, and snRNA in nucleus.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

RNAP III

A

transcribes tRNA in nucleoplasm.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

Lamina

A

Attach to chromatin, integral membrane proteins (emerin), and NPCs, provide anchorage sites for chromosomes, which bind at centromeres and telomeres, bind TFs to regulate transcription.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

CBs/Gems

A

sites of snoRNP and snRNP formation and maturation; also contain SMN (survival of motor neuron) proteins.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

Speckles

A

sites of pre-mRNA processing.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

Ran GTP

A

small G-protein that provides energy for NPC translocation; part of the Ran family; hydrolyzed by Ran-GAP.

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

Ran-GEF

A

an exchange factor that catalyzes the exchange of a GDP for a GTP on the Ran protein in the nucleus.

17
Q

Smooth ER

A

synthesizes steroid hormones, plasma lipoproteins, detoxifies material (Ex: in hepatocytes), controls muscle relaxation/contraction, degrades glycogen, and functions in gluconeogenesis.

18
Q

Rough ER

A

produces proteins destined for the ER, Golgi, lysosomes, endosomes, plasma membrane, and secretory vesicles; inner lumen = protein production and folding.

19
Q

BiP

A

lumenal RER protein that aids in folding proteins.

20
Q

Signal peptidase

A

cleaves N-terminus signal sequence as proteins enter the lumen.

MTM (9 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions