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Psych Cram > whoopie > Flashcards

whoopie Flashcards

1
Q

What is alexithymia?

A

inability to express feelings in words

many pts w/ “unfounded” somatic complaints are unable to express emotional hurt, fear, anger, etc. in words

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2
Q

Most common somatization symptoms?

A

1) nervousness
2) back pain
3) weakness

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3
Q

Timeframe for hypochondriasis?

A

> 6 mo

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4
Q

Tertiary amine TCAs? Are metabolized to what secodnary?

A

Imipramine (tertiary) -> desipramine (2)

Amitryptiline -> Nortryptiline

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5
Q

_______________ is useful in the treatment of depression caused by anxiety and sleep disturbances.

A

Trazodone

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6
Q

Most potent SNRI?

A

duloxetine

highly protein bound

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7
Q

Increased risk of birth defects w/ which SSRI?

A

Paroxetine

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8
Q

Which psychoactive drug can cause sick sinus syndrome?

A

Lithium

alternating bradycardia/tachycardia

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9
Q

Benzo that doesn’t need CYP?

A

lorazepam

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10
Q

Benzos that can be administered by injection?

A

Lorazepam (intermediate half life)

Diazepam (long half life but RAPID ONSET)

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11
Q

Rapid onset benzos?

A

Diazepam, Flurazepam (long half life)

Triazolam (short half life)

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12
Q

Benzos that are especially bad about causing withdrawal and should be tapered?

A

Triazolam, alprazolam

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13
Q

Benzo used in panic attacks?

A

alprazolam (has TCA action)

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14
Q

Patient has generalized anxiety disorder but doesn’t want sedation. Drug of choice?

A

Buspirone

partial agonist at serotonergic receptors -> diminishes serotonin activity while enhancing NE and DOP activity

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15
Q

Most common comorbid condition in kids w/ Tourrette’s and tics?

A

ADHD

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16
Q

Drugs of choice for comorbid Tourrette’s/tics and ADHS?

A

1) alpha2 agonists
2) stimulants (work for ADHD, not tics)
3) methylphenidate + alpha2 agonist

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17
Q

Which drugs have greatest demonstrated effect of reducing tics in randomized, placebo-controlled trials?

A

antipsychotics

only use alpha2 agonists if comorbid ADHD

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18
Q

why might acetaldehyde be pleasurable?

A

it is unpleasurable in the periphery

it is pleasurable in the CNS, where it combine w/ dopamine in the VTA to form salsinol

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19
Q

Blood alcohol level at which mood and personality changes occur?

A

100-150 mg/dL

20
Q

Blood alcohol level at which N/V, amnesia, dysarthria, ataxia occur?

A

150-400 mg/dL

21
Q

Blood alcohol levels at which coma, respiratory insufficiency, and death occur?

A

> 400 mg/dL

22
Q

2nd generation antipsychotics most likely to have CYP interactions?

A

Aripiprazole
Quetiapine
Risperidone
Ziprasidone

23
Q

2 things must be present to dx a child with intellectual disability:

A

1) significantly sub-average IQ
2) significant limitations in adaptive functioning (communication, self-care, life skills, health and safety skills, etc.)

24
Q

Most common cause of intellectual disability?

A

fetal alcohol syndrome

25
Q

Most common chromosomal cause of intellectual disability?

A

Down syndrome

26
Q

Most common heritable cause of intellectual disability?

A

Fragile X syndrome

27
Q

3 predominant types of ADHD?

A

1) inattentive type
2) predominantly hyperactive impulsive type
3) combined

28
Q

Timeframe for ADHD?

A

symptoms present for at least 6 months, onset before age 7

and impairment must occur in at least 2 settings such as home + school

29
Q

What is chronic motor or vocal tic disorder?

A

characterized as one of these b/c to have Tourrette’s you need to have both a motor AND vocal tic (though not necessarily at same time)

30
Q

What is transient tic disorder?

A

doesn’t meet criteria for Tourette’s because it hasn’t lasted long enough (1 year)

31
Q

Most effective treatment for enuresis?

A

enuresis alarms

drugs include desmopressin and imipramine

32
Q

Timeframe for separation anxiety disorder?

A

must be present for at least 4 wk

33
Q

What is reactive attachment disorder?

A

disturbed and developmentally inappropriate social relatedness that begins before age 5

associated w/ extreme neglect and/or grossly pathological care

34
Q

motor behavior that is repetitive, seemingly driven, and nonfunctional.

interferes with normal activities and/or causes bodily harm

A

stereotypic movement disorder

35
Q

Which antidepressant:

Elderly patient; patient w/ agitated depression or one w/ GI distress

A

citalopram

36
Q

Which antidepressant:

noncompliant or “forgetful” patient. or one w/ excessive fatigue

A

Fluoxetine (depot formulation available)

37
Q

Which antidepressant:

patient that needs an antidepressant that is least likely to produce initial anxiety or insomnia

A

Paroxetine

38
Q

Which antidepressant:

The medical/surgical patient on one or more medical drugs. initial activation and increased alertness desired.

A

sertraline

39
Q

Which antidepressant:

Patient w/ menopausal symptoms or failing an SSRI trial. at higher doses, pt with chronic pain

A

Venlafaxine

40
Q

Which antidepressant:

Patient w/ depression and chronic pain. Patient failing SSRI trial.

A

duloxetine

41
Q

Which antidepressant:

The medically ill patient with weight loss, insomnia, nausea

A

mirtazapine

42
Q

Which antidepressant:

the now depressed, potentially bipolar patient. apathetic, low energy patient. may be helpful for ADHD

A

buproprion

43
Q

Which antipsychotic contributes to serotonin syndrome?

A

haloperidol

44
Q

Which antiepileptic can precipitate serotonin syndrome?

A

valproate

45
Q

Which atypical do you give to kids?

A

risperidone

46
Q

Substrates of MDR1?

A

CVAP

citalopram
venlafaxine
amitryptiline
paroxetine

47
Q

Nonsubstrates of MDR1?

A

MF

mirtazapine
fluoxetine

Psych Cram (2 decks)

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