Wk3 Female Repro Histo Flashcards

1
Q

Ovarian cortex layer immediately beneath germinal epithelium:

A

Tunica albuginia

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2
Q

Embryological origin of primordial germ cells:

A

Yolk sac

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3
Q

When does the first meiotic division of oocyte occur?

A

just prior to ovulation

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4
Q

When does second meiotic division of oocyte occur?

A

at fertilization

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5
Q

Follicular development summary…

A

slide 23

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6
Q

5 phases of follicular development:

A
  1. Primordial follicle
  2. Unilaminar primary follicle
  3. Multilaminar primay follicle
  4. Secondary follicle (distinguished by presence of antrum)
  5. Graafian follicle (antrum is now continuous)
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7
Q

Single layer of flattened cells surrounding oocyte in primordial follicle:

A

Follicular cells

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8
Q

location of FSH receptors:

A

Follicular cells

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9
Q

Follicular cells become stratified columnar to form ________ in _________ follicles.

A

granulosa cells

primary follicles

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10
Q

Gel like layer surrounding oocyte in primary follicles – eosinophillic

A

zona pellucida

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11
Q

Forms just outside granulosa layer:

A

Theca interna

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12
Q

Antrum formation signifies which follicles:

A

Secondary

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13
Q

Produces androgens

A

Theca interna

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14
Q

granulosa cells surrounding oocyte and zona pellucida:

A

corona radiata

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15
Q

What signals final maturation of follicles:

A

LH –> first meiotic division, polar body formed

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16
Q

What triggers ovulation:

A

LH surge

17
Q

Cells with LH receptors

A

Granulosa

theca

18
Q

Two roles of FSH in folliculogenesis:

A
  1. stimulate granulosa cell growth and estrogen synthesis

2. (later) stimulates formation of LH receptors

19
Q

Two roles of LH in folliculogenesis:

A
  1. stimulates thecal cell growth and androgen production

2. stimulates progesterone production in granulosa cells

20
Q

Where are androgens converted to estrogen?

A

Granulosa cells

21
Q

Temporary glandular structure from remnants of ruptured follicle after ovulation:

A

Corpus luteum

22
Q

What do granulosa cells become in Corpus lutem?

A

granulosa lutein cells

produce estrogen and progesterone

23
Q

What do theca interna cells become in Corpus luteum:

A

theca lutein cells

produce estrogen and progesterone

24
Q

If no fertilization, what does Corpus luteum become?

A

corpora albicans

25
Q

What maintains corpus luteum after fertilization?

A

HCG from trophoblast

26
Q

Estrogen produced primarily by:

A

growing follicle

27
Q

Progesterone produce primarily by:

A

corpus luteum

**post ovulatory levels are high

**inhibits uterine contractions

28
Q

Found in follicular fluid, negative feedback on FSH release:

A

Inhibin

29
Q

Zone of uterine endometrium NOT shed during ovulation:

A

basal layer

30
Q

read the rest of the ppt:

A

structure and menstrual cycle

**do histotime