קהוט

Question 1

for what martin karpuls ,micheal levitt and arieh warshel get nobel?

Answer 1

simple energy functions for complex chemical systems

Question 2

free energy of folding consist of

Answer 2

enthalpy - entropy *temperature

Question 3

energy= sum of intractions between atom pairs

Answer 3

true

Question 4

donor is able to accept an electron in hydrogen bonds

Answer 4

false

Question 5

protein 3 structer -determind by interactions and bondes of side chains

Answer 5

true

Question 6

secondary structer is formed by H bonds in thr backbone and side chains

Answer 6

false

Question 7

a peptide bond formed by amino acide side chains?

Answer 7

false

Question 8

what increases the entropy of the solvent and responsible of reductipn of the freee energy in folding?

Answer 8

hydropobic effect

Question 9

the orange line symbolize attraction in VDW intractions?

Answer 9

True

Question 10

what is the amino acid M ?

Answer 10

Met ,Methionon
she is non-polar and hydrophobic , located in core , very rare ,and forms very weak interactions

Question 11

can I creat hydrophobic interactions?

Answer 11

yes

Question 11

is the 1 latter code of tryptophan trp is T?

Answer 11

no it is W

Question 12

Q

Answer 12

Gln Glutamine
the N in the side chain can be only a donor

Question 13

can T form H bondes ?

Answer 13

yes

Question 14

can N form H bondes ?

Answer 14

yes

Question 15

is D is Aspartate ?

Answer 15

yes

Question 16

R binds DNA?

Answer 16

yes

Question 17

dose K hase aliphatic part ?

Answer 17

yes

Question 18

C forms strong H bonds ?

Answer 18

yes

Question 19

S is frequntly phosphorylated ?

Answer 19

yes

Question 20

D forms H bondes bunt not salt bridegs ?

Answer 20

no the oppasit

Question 21

G allows the highest degree of backbone flexibility ?

Answer 21

yes

Question 22

what is Y ?

Answer 22

Tyrosin Tyr
can form H bondes , in the core , can form pi-pi interactions.

Question 22

D is a donor?

Answer 22

no

Question 23

is E charged ?

Answer 23

yes -

Question 24

V can have H bondes ?

Answer 24

no

Question 25

G breakes alpha helices because it is to small?

Answer 25

yes

Question 26

F can form pi-pi interactions?

Answer 26

yes

Question 27

P can be often found in ?

Answer 27

beta hairpins

Question 27

is proline flexibel ?

Answer 27

false

Question 28

S-S bondes can stabilize protein structure?

Answer 28

yes

Question 29

H is poseitivly charged in ph >6 ?

Answer 29

no

Question 30

metals in proteins are important for activity only but not structure ?

Answer 30

false

Question 31

secondery structure makes it possible to creat hydrophobic core ?

Answer 31

true

Question 32

in akpha helix position i forms a hydrogen bond whit i+4

Answer 32

true

Question 33

the amphipatic hliex fits a hydrophobic core ?

Answer 33

false

Question 34

in beta sheet H bondes formed between positions that are close in sequnce ?

Answer 34

false

Question 35

the ramachandran plot represents the amino acid prefrence of certin secondry structures?

Answer 35

false

Question 36

solving protein by X ray involves protein crystals ?

Answer 36

true