- Flashcards

(37 cards)

1
Q

Which type of hemorrhage is associated with a lucid interval?

A

Epidural

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2
Q

Best method of investigation of a CNS neoplasm?

A

MRI WITH CONTRAST

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3
Q

What do we give to decrease vasogenic oedema due to a brain tumor?

A

Dexamethasone

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4
Q

Management of acute onset optic neuritis?

A

Pulse steroids

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5
Q

Name 3 potentially epileptogenic drugs

A

ciprofloxacin
tramadol
anti malarial.

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6
Q

Drugs w/ important AED interactions

A

warfarin / digoxin/ oral ontraceptive / antibiotics

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7
Q

Gold standard investigation for the diagnosis of PNES?

A

Video EEG

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8
Q

Most important investigation for epilepsy

A

EEG + brain MRI

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9
Q

the single most useful laboratory study for the evaluation of patients with a suspected myopathy?

A

CK.

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10
Q

When taking muscle biopsies, which muscles should we choose?

A

UPPER EXTREMITIES: biceps
LOWER EXTREMITIES : vastus lateralis.

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11
Q

Most diagnostic investigations of DM?

A

Myositis specific autoantibodies
Muscle biopsy

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12
Q

Most diagnostic investigations of DM?

A

DermatoMyositis specific autoantibodies
Muscle biopsy

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13
Q

What muscle biopsy findings are diagnostic for dermatomyositis?

A

Atrophy in the perifasicular area.

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14
Q

Why is it important to differentiate immune mediated necrotizing myopathies from LGMD?

A

LMGD: non treatable/ non painful
immune mediated necrotizing myopathies: treatable/ painful

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15
Q

Autoantibodies in IMNM?

A

SRP + HMG-CoA reductase autoantibodies

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16
Q

Management of autoimmune myopathies? (DM/ anti syntehatse/ IMNM)

A
  • mild weakness: prednisone
  • moderate weakness: prednisone + Immunotherapy (methotrexate/ azathioprine/ microphrnylate mofetil) etc
  • cancer screening since they are common paraneoplastic syndromes.
17
Q

Diagnostic investigation of IBM?

A

MRI, shows asymmetrical muscle affection.

18
Q

Treatment of MG

A
  • Pyridostigmine (if AChR autoantibodies)
  • Plasma exchange + IVIg for exacerbation
  • PREDNISONE FIRST LINE mmunosuppressant
  • thymectomy
  • Rituximab for refractory disease
19
Q

Symptoms of Lambert Elton and its association with/ lung cancer?

A
  • gait dysfunction/lower extremity weakness,
  • areflexia or hyporeflexia
  • autonomic dysfunction.
    Associated with good prognosis is present w/ SCC.
20
Q

Inheritance pattern of dystrophinopathies?

21
Q

US findings of CMT?

A

Nerve thickening

22
Q

What investigation can we use to screen asymptomatic relatives of patients of CMT

23
Q

Is CMT demyelinating or axonal?

A

Could be both.

24
Q

Management of CMT?

A

rehabilitative and symptomatic

25
Management of chronic carpal tunnel syndrome
Rest and splints may help. • Diureticsandanti-inflammatorydrugs • Steroids injection into the carpal tunnel • Incise the transverse carpal ligament to decompress the tunnel.
26
Antibodies present in MMN?
anti-GM1
27
Management of MMN?
Favorable response to IVIg
28
“Cytoalbuminous dissociation “ is a finding in which comditons?
Aseptic meningitis GBS
29
Important findings in viral meningitis?
Temporal love enhancement on MRI Focal seizures (commonly of temporal lobe)
30
Important findings in viral meningitis?
Temporal love enhancement on MRI Focal seizures (commonly of temporal lobe)
31
Important findings in viral meningitis?
Temporal love enhancement on MRI Focal seizures (commonly of temporal lobe)
32
What investigation should be done for suspected fungal meningitis
Inidia ink test
33
MRI findings in bacterial meningitis?
Leptomeningel enhancement
34
Difference in treatments of CIDP vs GBS?
Gbs: Plasma exchange + IVIg. DO NOT GIVE STEROIDS!!! CIDP: - PREDNISOLONE - Plasma exchange + IVIg
35
What is titubation a sign of?
Cerebellar dysfunction
36
Triggers of a seizure
MISSED ANTIEPILEPTIC DOSE ALCOHOL/ DRUGS SLEEP DEPRIVATION HYPOGLYCEMIA (skipping meals) PHOTOSENSITIVITY ( flashing lights) DEHYDRATION MENSES IN SOME WOMEN
37
Most important location of intra cerebral hematoma on top of hypertension?
Lenticulostriate arteries which supply the BG and internal Capsul The largest medial one (Recurrent artery of H𝑒ubner) is known as the artery of internal hemorrhage M.)