- Flashcards
(37 cards)
Which type of hemorrhage is associated with a lucid interval?
Epidural
Best method of investigation of a CNS neoplasm?
MRI WITH CONTRAST
What do we give to decrease vasogenic oedema due to a brain tumor?
Dexamethasone
Management of acute onset optic neuritis?
Pulse steroids
Name 3 potentially epileptogenic drugs
ciprofloxacin
tramadol
anti malarial.
Drugs w/ important AED interactions
warfarin / digoxin/ oral ontraceptive / antibiotics
Gold standard investigation for the diagnosis of PNES?
Video EEG
Most important investigation for epilepsy
EEG + brain MRI
the single most useful laboratory study for the evaluation of patients with a suspected myopathy?
CK.
When taking muscle biopsies, which muscles should we choose?
UPPER EXTREMITIES: biceps
LOWER EXTREMITIES : vastus lateralis.
Most diagnostic investigations of DM?
Myositis specific autoantibodies
Muscle biopsy
Most diagnostic investigations of DM?
DermatoMyositis specific autoantibodies
Muscle biopsy
What muscle biopsy findings are diagnostic for dermatomyositis?
Atrophy in the perifasicular area.
Why is it important to differentiate immune mediated necrotizing myopathies from LGMD?
LMGD: non treatable/ non painful
immune mediated necrotizing myopathies: treatable/ painful
Autoantibodies in IMNM?
SRP + HMG-CoA reductase autoantibodies
Management of autoimmune myopathies? (DM/ anti syntehatse/ IMNM)
- mild weakness: prednisone
- moderate weakness: prednisone + Immunotherapy (methotrexate/ azathioprine/ microphrnylate mofetil) etc
- cancer screening since they are common paraneoplastic syndromes.
Diagnostic investigation of IBM?
MRI, shows asymmetrical muscle affection.
Treatment of MG
- Pyridostigmine (if AChR autoantibodies)
- Plasma exchange + IVIg for exacerbation
- PREDNISONE FIRST LINE mmunosuppressant
- thymectomy
- Rituximab for refractory disease
Symptoms of Lambert Elton and its association with/ lung cancer?
- gait dysfunction/lower extremity weakness,
- areflexia or hyporeflexia
- autonomic dysfunction.
Associated with good prognosis is present w/ SCC.
Inheritance pattern of dystrophinopathies?
X linked.
US findings of CMT?
Nerve thickening
What investigation can we use to screen asymptomatic relatives of patients of CMT
NC
Is CMT demyelinating or axonal?
Could be both.
Management of CMT?
rehabilitative and symptomatic