012915 endocrine physio Flashcards Preview

ER part 1 > 012915 endocrine physio > Flashcards

Flashcards in 012915 endocrine physio Deck (11)
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1
Q

hormone classes

A

steroids
thyroid hormones
polypeptides, proteins, glycoproteins, catecholamines

2
Q

which hormone class is lipophilic?

A

steroid

thyroid

3
Q

steroids are all synthesized from

A

some form of cholesterol

4
Q

glycoproteins (LH, FSH, TSH, hcG) all have the same of what kind of unit?

A

alpha (specificity is in beta unit)

5
Q

rate limiting step for all steroidogenic pathways

A

steroidogenic acute regulatory protein (STAR) mediation of cholesterol uptake from the cytosol to the inner mito membrane where P450scc is

6
Q

thyroid hormone receptors are located where

A

in nucleus

7
Q

how can T4 be made more potent?

A

by being converted to T3 in target tissue by the enzyme iodinase (like the ex of testosterone being converted to DHT)

8
Q

describe positive feedback loop in oxytocin (delivery)

A

stretch of cervix-signal goes to hypothalamus, which goes to posterior pituitary to stimulate oxytocin release to increase uterine contraction

9
Q

in secondary hypofxn, what is the target gland fxn level and the controlling hormone level?

A

target gland fxn-decreased

controlling hormone-decreased or normal

10
Q

ex of secondary hypofxn

A

80% of corticotrophs (ACTH-producing cells in anterior pituitary) are gone. the 20% remaining can’t make enough ACTH to keep cortisol normal

11
Q

in secondary hyperfxn, what are target gland fxn level and controlling hormone levels?

A

target gland fxn-increased

controlling hormone-increased or normal