05. Animal Form and Function Flashcards

1
Q

What are differences between nervous and endocrine systems?

A

TNRTD

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2
Q

What is nervous organization of cnidaria and an example?

A

Nerve net, Hydra

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3
Q

Nervous organization of platyhelminthese and an example

A

Brain and longitudinal nerve cord

Planaria

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4
Q

What is the common nervous organization of snnelid and arthropod?

A

Brain
Ventral nerve cord
Segmented ganglia

Ex1-leech
Ex2 cockroach

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5
Q

What is the nervous prganization of echnodermata and an example

A

Nerve ring and radial nerves
Sea star

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6
Q

What I the nervous organization of chordata

A

Brain
Spinal cord
Nerves and ganglia
Ex.gecko

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7
Q

What does the central nervous system consist of

A

Brain
Spinal cord

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8
Q

What does the anterior part of the nervous system enlarge and form?

A

Forebrain
Midbrain
Hindbrain

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9
Q

What is the location of the ventricles?

A

3 ventricles in the forebrain
1 ventricle in the hindbrain

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10
Q

What is the function of C.S.F?

A

It helps maintain uniform pressure within the central nervous system
Acts as a shock absorber between the brain and skull
Helps circulate nutrients and hormones
Removes waste products

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11
Q

How is the brain protected from physical injuries?

A

The brain is enclosed by the skull

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12
Q

How is the spinal cord protected from physical injuries?

A

It is surrounded by vertebrae which forms the vertebral column

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13
Q

How is the central nervous system protected?

A

By 3 layers of tissues called meninges
They are dura mater (outermost layer), pia mater(innermost layer) and the arachnoid mater(the layer in-between these two layers)

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14
Q

What does the forebrain give rise to?

A

Cerebrum
Thalamus
Hypothalamus
Pineal Body

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15
Q

What does the midbrain give rise to?

A

Part of the brainstem

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16
Q

What does the hindbrain give rise to?

A

Cerebellum
Pons varolii
Medulla oblongata

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17
Q

What is the largest part of the human brain?

A

Cerebrum

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18
Q

What is the cerebrum composed of?

A

Nerve cell bodies (grey matter) forming the cerebral cortex
Deeper layers consist of nerve fibers (white matter)

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19
Q

What connects the 2 cerebral hemispheres?

A

Corpus Callosum

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20
Q

What is the corpus callosum made up of?

A

White matter

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21
Q

What do the infoldings of the cerebral cortex do?

A

It increases the area of the cerebrum

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22
Q

What are the 4 lobes of the cerebral hemisphere?

A

Frontal Lobe
Temporal Lobe
Parietal Lobe
Occipital Lobe

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23
Q

What are the main functions of the cerebral cortex?

A

Sensory areas RECIEVE and PROCESS sensory information including the perception of pain, temperature, touch, taste, smell, sight and hearing

Association areas are responsible for recognition, integration , and interpretation of sensory information and the processing of complex mental functions such as MEMORY, INTELLIGENCE, REASONING, JUDGEMENT and EMOTIONS.

Motor areas are responsible for directing skeletal (voluntary) muscle movement through the initiation and control of voluntary muscle contraction

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24
Q

What is the location of thalamus?

A

Within the cerebral hemisphere just below the corpus callosum

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25
What is thalamus comprised of?
Grey and white matter
26
What are the functions of the thalamus?
It acts as the main input center of sensory information from special sense organs and special sense receptors in the skin and integral organs Sensory information is sorted and directed to specific locations in the cerebral cortex for processing and perception. It relates and distributes nerve impulses for most parts of the brain and cerebral cortex
27
What is the location of the hypothalamus?
Below and in front of the thalamus immediately above the pituitary gland.
28
What links the hypothalamus to the posterior lobe of pituitary gland?
Nerve fibers
29
What links the hypothalamus to the anterior lobe of the pituitary gland?
A complex system of blood vessels (portal blood vessels)
30
What are the functions of the hypothalamus?
Regulates body temperature Regulates thirst and water balance Regulates appetite Regulates sleep and wake cycles Controls the autonomic nervous system Initiates fight/flight response Source for posterior pituitary hormone and releasing hormones that act on the anterior pituitary Plays a role in sexual behavior
31
Where is the midbrain located?
It is the upper part of the brainstem located in the cerebrum above and pons below surrounding the C.S.F fluid filled connection of third and fourth ventricles
32
What does the midbrain contain?
Aggregates of nerve cell bodies and nerve tracts
33
What is function of nerve tracts of the midbrain?
Connects the cerebrum with the lower brain and spinal cord
34
What are the functions of the midbrain?
Acts as a relay station for ascending and descending nerve fibers Receives and integrates sensory information (auditory and visual) and sends them to particular regions of the forebrain Coordinates auditory and visual reflexes
35
What is the location of pons varolii?
In front of cerebellum, below midbrain, above medulla oblongata
36
What does the pons varolii contain?
1. nerve fibers that form a bridge between two hemispheres of the cerebellum 2. nerve fibers passing between higher levels of the brain and spinal cord 3. groups of nerve cell bodies
37
What do groups of cell bodies form?
centers that regulate respiration some act as relay stations
38
What are the functions of pons varolii?
Transferring information between PNS and midbrain and forebrain Coordinating large scale body movements like running and climbing Together with medulla oblongata, helps regulate respiration
39
Where is medulla oblongata?
Lowest part of the brain stem which extends from the pons above and continuous with the spinal cord below
40
What are the centers the medulla oblongata contains?
Respiratory center Cardiovascular center Reflex center
41
What are the functions of the medulla oblongata?
Transfers information between PNS and midbrain and forebrain Coordinates various body movements like running and climbing
42
What is the location of the cerebellum?
It is located behind the pons varoli below the posterior portion of the cerebrum
43
What is cerebellum made of?
Two hemispheres
44
What are the functions of the cerebellum?
coordinates voluntary muscle movements Maintains posture and balance Helps in learning and remembering motor skills
45
What are the common functions of the medulla oblangata and the pons varolii?
Coordinates large scale body movements like running and climbing Helps to regulate respiration
46
What are the common functions of thalamus and midbrain?
Act as a relay station
47
What are the functions of the spinal cord?
Links the central nervous system to sensory and motor neurons Facilitates nerve impulse propagation towards and away from the brain Coordinates and produces reflexes
48
What does the center of the spinal cord contain?
central canal (surrounded by grey matter) outer region (made of white matter)
49
What is the peripheral nervous system made up of?
Cranial nerves Spinal nerves Autonomic nervous system (with ganglia)
50
What is the function of PNS?
It transmits impulses to and from the CNS Regulates both animal movement and its internal environment
51
What does the sympathetic stimulation prepare the body for?
Dealing with stressful or exciting situations and energy generating situations (Fight/Flight)
52
Where do sympathetic nerves exit from?
Only from the spinal cord
53
What neurotransmitter is secreted by sympathetic nerve system?
Norepinephrine
54
What does the parasympathetic stimulation prepare the body for?
Causes opposite responses to sympathetic stimulations that promote calming or a return-to-self maintenance functions Rest and digest
55
What makes sympathetic and parasympathetic nervous systems differ from each other?
Overall functions Organization Signal released
56
Where do parasympathetic nerves exit from?
Spinal cord as spinal nerves or cranial nerves At the base of the brain
57
What is the neurotransmitter secreted by parasympathetic division?
Acetylcholine
58
What do different neurotransmitters enable sympathetic and parasympathetic nervous systems to do?
Bring about opposite effects in different organs such as lung, heart, intestine and bladder.
59
Name examples for parasympathetic division
Constricts eye pupil Constricts bronchi in lungs Slows heart
60
How does the parasympathetic nervous system help in digestion?
Stimulates activity of stomach and intestines Stimulates activity of pancreas Stimulates gall bladder
61
How does the parasympathetic nervous system function in rest?
Promotes emptying of bladder Promotes erection of genitalia
62
What are the functions of the sympathetic nervous system?
1. Dilates pupil eye 2, Inhibits salivary gland secretion 3. Relaxes bronchi in the lungs 4. Accelerates the heart rate 5. inhibits the activity of the stomach and the intestines 6. Inhibits the activity of pancreas 7. Stimulates glucose release from liver inhibits the gall bladder 8. Stimulates adrenal medulla 9. inhibits emptying the bladder 10. promotes ejaculation and vaginal contractions
63
What does the speed of the conduction depend on?
1. Diameter of the axon- The conduction increases with increase in the axon diameter 2. Presence of myelinated axon- axon potential jumps from one node of Ranvier to next
64
What are examples if neurotransmitters?
1. Acetylcholine 2.some amino acids 3. Biogenic amines 4. Neuropeptides 5. Some gases
65
What are examples of chemoreceptors?
taste and olfactory receptors To Detect specific chemicals such as CO2 circulating in the blood
66
What are examples of chemoreceptors?
taste and olfactory receptors Detect specific chemicals such as CO2 circulating in the blood
67
Where are the olfactory receptors?
Upper portion of the epithelium of the nasal cavity
68
What are locations of thermo receptors?
Skin - detect the body surface temperature Hypothalamus - detects the temperature of the blood circulating through internal organs
69
What are the thermal receptors found in the skin?
Krause end bulbs detect cold Rufinicorpuscles detect warmth Free nerve endings detect both the warm and cold
70
What are the thermoreceptors found in the hypothalamus?
Specialized neurons
71
What are examples for mechanoreceptors?
Touch receptors Pressure receptors Vibration receptors
72
What are examples for touch receptors?
Meissner corpuscles - sensitive to light pressure Merkel disks - sensitive to light touch Free nerve endings
73
What are the four main types of tissues?
1. Epithelial tissue 2. Connective tissue 3. Muscle tissue 4. Nerve tissue
74
What are the characteristics of epithelial tissues?
*It covers external or internal free surfaces and organs. *The cells of the tissues are closely packed. * Cells of epithelial tissue have both apical and basal surfaces where apical surface remains free and the basal surface attached to the basement membrane. *No blood vessels in the tissue. *Tissue gets nutrients and oxygen from the underneath connective tissue.
75
What are the functions of epithelial tissues?
Protection (e.g. barrier against mechanical injury, pathogens, barrier against fluid loss Secretion (e.g. enzymes, hormones, mucus, sweat) Absorption (e.g. nutrients, respiratory gases ) There are two general types according to the number
76
What are the general types of tissues according to the number of cell layers on the basement layers?
1. Simple epithelia 2. Compound epithelia
77
What are the features of simple squamous epithelium?
1. They are thin and leaky 2. Found in places where materials exchange by diffusion
78
What are the examples for simple squamous epithelium?
Blood capillaries Alveoli
79
What are the features of cuboidal epithelium?
1. Dice shaped cells 2. Specialized for secretion 3.
80
Where are simple cuboidal epithelial cells are found?
Kidney tubules Glands like thyroid and salivary glands
81
Where are simple cuboidal epithelial cells are found?
Kidney tubules Glands like thyroid and salivary glands
82
What are the features of simple columnar epithelium?
1. Single cell layer 2. Large brick shaped cells 3. Found in places where secretion or active absorption is important
83
What are examples for simple columnar epithelial cells?
Intestinal lining
84
What are the features of the pseudostratified columnar epithelium?
This tissue consists of a single cell layer. Cells are not of equal height. Nuclei of cells are located at different level. Appear as several layers. In many vertebrates this epithelium has ciliated cells that form a mucous membrane and the cilia help to sweep the mucous along the surface.
85
What are the examples of pseudostratified epithelial tissues?
Nasal passage trachea
86
What are the features of the stratified squamous epithelium?
This tissue is composed of a number of layers of cells. This epithelium regenerates rapidly. Cell division produces new cells near the basement membrane. The old cells are sloughed off and replaced by the new cells .
87
Where are stratified squamous epithelium found in?
on surfaces where they are subjected to abrasion such as outer skin, lining of mouth, anus, vagina
88
What are the features of the connective tissue?
Connective tissues are the most abundant tissues in the body that help to connect organs and tissues together structurally and functionally. These types of tissue consist of different types of cells scattered in a large amount of extracellular matrix containing different types of fibers. Matrix may be a semisolid (Jelly-like), liquid or solid (dense and rigid). Different types of cells can be found in the matrix such as fibroblasts (secrete fiber proteins), macrophages (engulf foreign particles or any cell debris by phagocytosis) and mast cells ( secrete heparin and histamine) in addition fat cells (storage and insulation) and leukocytes (protection) are found in some connective tissues. There are three different types of fibers. They are collagen fibers (provide strength and flexibility), reticular fibers (join connective tissues to adjacent tissues) and elastic fibers (make tissue elastic).
89
What are the common functions of the connective tissues?
Binding and structural support Protection Transport of materials Insulation
90
What are the different types of the connective tissue?
loose connective tissue (Areolar tissue) Fibrous connective tissue (Dense connective tissue) adipose tissue, blood cartilage bone .
91
What are the features of the loose connective tissue?
This tissue is the most widely distributed connective tissue type in the vertebrate body. This can be considered as the generalized type of connective tissue. Types of cells in this tissue are fibroblasts, macrophages, mast cells, leukocytes and fat cells. All three types of fibers are found in this tissue. Fibers are loosely arranged and wavy in nature
92
What is the function of loose connective tissue?
This tissue binds epithelia and the underlying tissue. Therefore this holds organs in place.
93
Where is the loose connective tissue is located in?
under the skin and throughout the body
94
What are the common features of the fibrous connective tissue?
This tissue is densely packed with collagen fibers. Therefore the matrix is relatively reduced contains fewer cells (fibrocytes)
95
Where are the fibrous connective tissues found in?
tendons (attach muscle to bones) ligaments (connect bones and joints) (Here, the tensile strength is required)
96
What are the features of the adipose tissue?
This tissue is packed with adipose cells. Each adipose cell contains a large fat droplet. This is a specialized type of loose connective tissue which pads and insulates the body and stores fuel as fat molecules.
97
What is the function of the adipose tissue?
act as a thermal insulator energy store.
98
Where is the adipose tissue located in?
under the skin
99
What are the features of the blood tissue?
Specialized connective tissue The matrix is not secreted by the cells Fibers are formed only during blood clotting process. The extracellular matrix of the blood is liquid. It is called as plasma. The blood plasma contains salts, water and dissolved proteins. Red blood cells (transport respiratory gases), white blood cells (defense) and platelets (blood clotting) are suspended in the blood plasma.
100
What are the main functions of the blood tissue?
Transport of materials protection osmoregulation.
101
What are the features of the cartilage?
This tissue consists of a matrix composed of chondroitin sulphate which is a rubbery protein-carbohydrate complex. Collagen fibers and chondrocytes are embedded in the matrix. Chondrocytes secrete chondroitin sulphate and collagen fibers.
102
What does the cartilage do?
This tissue provides support and flexibility in places such as trachea, intervertebral discs.
103
What are the features of the bone tissue?
It is a mineralized connective tissue. Matrix consists of collagen fibres and inorganic salts. Inorganic salts are Calcium, magnesium and phosphate ions. Cells are osteoblasts (bone forming cells) and osteocytes (mature bone cells that maintain bone tissue). Osteocytes are enclosed within lacunae. The mammalian hard bone has repeating units called osteons. Each osteons has a concentric layer of mineralized materials.
104
What is the repeating unit of the mammalian hard bone?
Osteon
105
Describe the structure of the osteon
Each osteons has a concentric layer of mineralized materials. At the center of the osteon is a central canal containing blood vessels and nerves.
106
What is the function of the bone?
This tissue forms the endoskeleton of most vertebrates Provides support and strength to the body.
107
What is the function of the muscle tissue?
Muscle tissue is responsible for movement
108
What are the features of the muscle tissue?
The cells in the muscle tissue are composed of actin and myosin proteins. This tissue is able to contract and relax.
109
What are the three basic types of muscle tissues?
smooth muscle skeletal muscle cardiac muscle tissues.
110
What are the features of the smooth muscle tissue?
The cells of the smooth muscle tissue are spindle shaped and uninucleated. Cells lack striations. This tissue is responsible for involuntary body functions (e.g. churning of stomach, constriction of arteries)
111
Where can we find the smooth muscle tissue?
digestive tract urinary bladder arteries other internal organs.
112
What are the features of the skeletal muscle tissue?
They are composed of bundles of long cells with multi nuclei. Cells are striated. The contractile units of this muscle cells are called sarcomeres. The arrangement of the sarcomere gives the striated appearance The muscles are generally attached to the skeletal system
113
What is the function of the skeletal muscle tissue?
Helps in voluntary muscle movement
114
What are the features of the cardiac muscle tissue?
They are composed of uninucleated cells They are interconnected via intercalated discs. Cells are striated with sarcomeres. Intercalated disks help relay signals from cell to cell and synchronize heart contraction
115
Where can we find the cardiac muscle tissue?
Intercalated disks help relay signals from cell to cell and synchronize heart contraction
116
Where can we find the cardiac muscle tissues?
only found in the wall of the heart.
117
What are the two types of cells of the nervous tissue?
Neurons Glial cells
118
What is the function of the nervous tissue?
Neurons receive, process and transmit nerve impulses.
119
What are the parts of the neuron?
Cell body dendrites axon
120
What is the structural unit of the nervous system?
Nervous tissue
121
What is the function of dendrites?
Dendrites and cell body is used to receive nerve impulses from other neurons.
122
What is the axon used for?
Axon is used to transmit impulses to other neurons, cells or muscles. Axons are bundled together into nerves
123
What are neuroglia?
Neuroglial cells are supportive cells of neurons
124
What are the functions of the neuroglia?
nourishment of nerve cells insulation of nerve cells replenishing neurons and sometimes modulate neuron functions. (n i r s)
125
What are examples of heterotrophs?
animals fungi majority of bacteria
126
What are the two types of heterotrophic nutrition?
1. Holozoic nutrition 2. Symbiosis
127
What are the five main stages of the holozoic nutrition?
1. Ingestion 2. Digestion 3. Absorption 4. Assimilation 5. Egestion
128
According to what do different animals have different mode of nutrition?
1. Diet 2. environment
129
How can digestion occur during the holozoic mode of nutrition?
1. Mechanically (teeth or muscle contractions) 2. Chemically (by enzymes)
130
What are examples of filter feeders?
Clams Oysters
131
How do clams and oysters feed themselves?
feed on small pieces of food in the water that passes over their gills. Cilia in the gills sweep the food particles to the animal’s mouth in a film of mucus.
132
What are the examples for fluid feeders?
Mosquitoes-suck human blood Aphids- suck phloem sap of plants Bees and humming birds suck -honey from flowers
133
What are examples for bulk feeders?
Most animals including humans
134
What are the different types of adaptations used by bulk feeders to tear and capture prey?
jaws teeth tentacles claws poisonous fangs
135
Give an example for mutualistic association of heterotrophic organisms
*Cellulose digesting microorganisms in Ruminants and Termites
136
Give an example for parasitism association of heterotrophic organisms
Tape worm and humans Lice and humans
137
Name an example for commensalism of heterotrophic organisms
Barnacles attached to the whales
138
Name an example for commensalism of heterotrophic organisms
Barnacles attached to the whales
139
Where do parasites live in?
Parasites live either within or on the host and derive its nourishment
140
What does the digestive system consist of?
Alimentary canal associated glands
141
What does the alimentary canal include of human digestive system?
Oral cavity pharynx esophagus stomach small intestine large intestine rectum anus
142
What are the associated glands of the human digestive system?
salivary glands pancreas liver
143
Why is the food cut, mashed and grounded easily?
This makes it easier to swallow food increase the surface area for digestion.
144
Why is the food cut, mashed and grounded easily?
This makes it easier to swallow food increase the surface area for digestion.
145
What are the two ways by which the saliva entered into the mouth?
Releasing saliva into the oral cavity occurs when food enters the oral cavity due to a nervous reflex. Saliva is also released into the mouth before food is ingested due to various other stimuli. e.g. sight, odor of food, etc.
146
What do the saliva contain?
water, amylase, mucus (a viscous mixture of salts, cells and slippery glycoprotein called mucins), buffers and anti microbial components.
147
What are the functions of the saliva
• Salivary amylase: Chemical digestion of polysaccharides (e.g. starch) into smaller polysaccharides and disaccharide maltose. • Water: Liquefy food and provide watery medium for chemical digestion. Aids in taste reception. • Mucus: Lubrication of food which makes it easier for swallowing. Clean the mouth and protects the lining of the mouth from abrasion. • Antimicrobial substances such as immunoglobulin and lysozymes: Protect against bacteria that enter the mouth. • Buffers prevent tooth decay by neutralizing acid
148
What is the function of the tongue?
Helps to mix the food with saliva and make bolus of food that makes easier for swallowing. Then helps to push the bolus into the posterior part of the oral cavity and into the pharynx.
149
What is the function of the pharynx?
a common passage of the respiratory tract and the digestive tract. The pharynx leads to the esophagus.
150
What does the wall of esophagus contain ?
Both skeletal and smooth muscles
151
What is the location of skeletal muscles and their function?
located towards the uppermost part of the esophagus and these muscles function during swallowing
152
What does the rest of esophagus contain?
Smooth muscles that are involved in the process of peristalsis During this process the food bolus is pushed along the esophagus which is a alternative wave of rhythmic contractions and relaxations of the smooth muscles lining the esophagus.
153
What is the stomach?
The stomach is a J- shaped dilated sac in the abdominal cavity.
154
Describe the nature of the inner surface of the stomach
The inner surface of the stomach is highly folded and contains large number of pits that leads to gastric glands.
155
What are the three types of cells of the gastric gland?
mucus cells chief cells parietal cells.
156
Describe the nature of the stomach wall
It is very elastic
157
What does the distal part of the stomach connect with?
With the small intestine
158
Where are the stomach sphincters found in?
Sphincters are found at the junctions between esophagus and stomach (cardiac sphincter) Junction between the stomach and the small intestine(pyloric sphincter). They are made up of circular smooth muscles.
159
What does these sphincters regulate?
These sphincters help to regulate the passage of materials between these organs.
160
What secretes gastric juice of the stomach?
Gastric glands
161
What does the gastric juice consist of?
mucus pepsinogen HCl
162
Mucus is secreted by what cells of stomach?
Mucus cells
163
Pepsinogen(inactive form of pepsin) is secreted by what cells in the stomach?
Chief cells
164
What do parietal cells of the stomach do?
Parietal cells release hydrogen ions and chloride ions separately into the stomach lumen where HCl is formed. Pepsinogen is initially converted into pepsin by HCl.
165
What do the activated pepsin of the stomach do?
help to activate remaining pepsinogen molecules. This activated pepsin initiates the chemical digestion of proteins in the stomach.
166
What does the churning action of the stomach do?
It Initiates the chemical digestion of proteins in the stomach. The churning action of the stomach facilitates the chemical digestion. This is a series of muscle contraction and relaxation. This process mixes the swallowed food with gastric juice.
167
What are proteins hydrolyzed into in the stomach?
Into small polypeptides by pepsin
168
What does the food mixed with gastric juice form?
In the stomach food is mixed with gastric juice forming chyme (partially digested semisolid, acidic, food mass).
169
How is the stomach lining protected from the digestion of HCl and pepsin?
Enzymes are secreted in to the lumen as an inactive enzyme; Gastric glands secrete mucus that protect against self-digestion of the stomach lining ; Every three days, cell division adds a new epithelial cell layer which replaces the destroyed/ damaged cells in the lining of the stomach.
170
What are the functions of the stomach?
• Act as a temporary reservoir for food due to high convolution and very elastic wall. • Mechanical digestion of food by churning action due to muscular contraction. • Produce gastric juice which starts the chemical digestion of proteins to polypeptide by pepsin • Absorption of some materials such as water, alcohol and some drugs • Non specific defense-HCl kills microbes • Small jets of gastric contents push out through pyloric sphincter as chyme • Secretion of gastrin hormone which regulates digestion in the stomach.
171
What is the longest organ in the human alimentary canal?
Small intestine
172
What is the duodenum? Function? What is the jejunum? Function? What is the ileum? Function?
1. C shaped curve, around the head of the pancreas. Most of the digestion is completed in the duodenum. 2. The jejunum is middle part of the small intestine. (The major sites for nutrient absorption are jejunum and ileum. ) 3. The ileum is the terminal part of the small intestine. (The major sites for nutrient absorption are jejunum and ileum.)
173
How is the surface area of the small intestine increased?
by permanent circular folds and villi. The villi are tiny finger like projections of the intestinal wall
174
From what does the small intestine receive chyme from?
Small intestine receives chyme from the stomach.
175
What aids in receiving the chyme?
Peristaltic contractions
176
What sphincter regulates the passing of the chyme into the small intestine?
pyloric sphincter
177
What is the chyme of the small intestine mixed with?
The chyme is mixed with secretions of glands in intestinal wall and secretions of pancreas and liver.
178
What does the epithelium and the duodenum secrete?
several digestive enzymes. Glands of the intestinal wall secrete enzymes such as Disaccharidases, Dipeptidases, Carboxypeptidases, Aminopeptidases, Nucleotidases, Nucleosidases and Phosphotases. (CANCLT)
179
What are the two hormones secreted by the duodenum?
cholecystokinin secretin
180
What does the cholecystokinin stimulate?
release of pancreatic juice
181
What does secretin stimulate?
Stimulates the bile secretion
182
What does the pancreatic juice contain?
enzymes such as Trypsin, Chymotrypsin , Pancreatic amylase , Pancreatic Carboxypeptidases, Pancreatic Nucleases and Pancreatic Lipases (CANCLT) ad bicarbonates in addition
183
What does the liver secrete?
Bile
184
What is bile stored in?
Gall bladder, until released into the duodenum
185
What does the bile contain?
Bile salts
186
What do the bile salts do?
act as emulsifiers that help in fat digestion and absorption.
187
How does the carbohydrate digestion occur in the small intestine?
Pancreatic amylase catalyze the conversion of polysaccharides (e.g. starch) into disaccharides. Intestinal disaccharidases catalyze the conversion of disaccharides into monosaccharides
188
How does protein digestion take place in the small intestine?
Tripsin and Chymotripsin catalyse the conversion of small polypeptides into smaller polypeptides. These smaller polypeptides are converted to small peptides and amino acids by the catalytic action of Panceratic carboxypeptidases. Proteases secreted by the intestinal epithelium (Dipeptidases, Carboxypeptidases and Aminopeptidases) catalyse the conversion of small peptides into amino acids.
189
How does fat digestion take place in the stomach?
Digestion of fats (triglycerides) starts in the small intestine. First bile salts emulsify fats. Next Pancreatic lipase catalyse the conversion of these fats into fatty acids, glycerol and monoglycerides.
190
How does nucleic acid digestion take place in the small intestine?
Digestion of nucleic acids start in the small intestine. Pancreatic nucleases catalyse the conversion of DNA and RNA into nucleotides. These nucleotides are eventually converted into nitrogenous bases, sugars and phosphates by the catalytic action of intestinal Nucleotidases, Nucleosidases and Phosphatases.
191
What are the adaptations of the small intestine for effective digestion?
For effective absorption, the surface area of the intestinal wall has been increased with three structural modifications: *heavy permanent foldings, *finger like projections called villi in the intestinal wall *finger like microscopic projections called microvilli in the epithelial cells of the villi. These micro villi are exposed into the intestinal lumen, it gives the appearance of brush (brush border).
192
How does the transportation
193
What are the two ways of transport across the small intestine?
Active Passive
194
How is fructose absorbed by the small intestine?
By facilitated diffusion
195
What are actively transported into the epithelial cells of the small intestine?
Amino acids Small peptides Vitamins Most glucose molecules
196
Name the pathway of nutrients after the absorption process of the small intestine?
nutrients from the epithelial cells are transported into the blood capillaries in the villi blood capillaries are converged into the hepatic portal veins nutrients are carried in to the liver via the hepatic portal veins. from the liver, this nutrient filled blood is transported into the tissues. { Nutrients in the epithelial cells -> hepatic portal vein -> liver -> tissues }
197
What is the different pathway in which the absorption of some products of fat take place?
Fatty acids and monoglycerides are absorbed into the cell through microvilli. Within the cells triglycerides are reformed and they are incorporated into water soluble globules called chylomicrons. These chylomicrons are transported into the lacteal and then into the blood vessels through lymph. Then they are transported throughout the body via the circulatory system. { fats and monoglycerides -> turns to water soluble globules called chylomicrons -> lacteals -> lymph -> blood vessels -> c.v.s }
198
What is the large intestine?
The large intestine is the terminal end of the alimentary canal.
199
What are the three regions of the large intestine?
colon (proximal part) cecum rectum
200
How is the small intestine connected to the large intestine?
at a ‘T’ shaped junction.
201
What is the finger like projection in the cecum?
appendix
202
What does the colon leads to?
The colon leads to the rectum and anus.
203
Why is the caecum important?
for fermentation of indigested materials by microbes, especially in animals that eat large amount of plant matter.
204
Name the functions of the colon of the large intestine?
completes the reabsorption of water synthesize some Vitamin B complexes Vitamin K and folic acid with the help of microbes move feces (consists of undigested matter such as fibres) along the colon by peristalsis.
205
What are the functions of the rectum in the large intestine?
Stores feces until they are eliminated Presence of two sphincters between the rectum and anus can regulate feces movement Strong contractions in the colon trigger the defecation
206
Name the nature of the structure of the pancreas
The pancreas is a pale grey gland which consists of a broad head, a body and a narrow tail. Head is in the curve of the duodenum. Pancreas is both an exocrine and endocrine gland.
207
What is the exocrine part of the pancreas consisted of?
The exocrine part consists of a large number of lobules made up of small acini, the walls of which consist of secretary cells. Each lobule is drained by a tiny duct and these unite eventually to form the pancreatic duct which joins with bile duct to form hepato pancreatic duct and opens into the duodenum at its midpoint
208
What does the exocrine part of the pancreas secrete and what does it include?
Exocrine part of the pancreas secretes pancreatic juice. The components of the pancreatic juice are bicarbonate, carbohydrate digesting enzymes (pancreatic amylase), pancreatic lipase, nucleases and inactive form of protein digesting enzymes (trypsinogen and chymotrypsin). These inactive enzymes are converted to active enzymes(trypsin and chymotrypsin) upon secretion into the lumen of the duodenum.
209
What does the endocrine part of the pancreas contain?
Endocrine part of the pancreas is the islets of Langerhans, which consist of group of specialized cells. They do not have ducts
210
What does the islets of the Langerhans do?
*Islets of Langerhans secrete hormones, glucagon and insulin which are involved in glucose homeostasis.
211
What is the largest gland in the body?
Liver
212
Describe the nature of the liver
Its upper and anterior surfaces are smooth and convex. Its posterior surface is irregular in outline
213
How many lobes are there in the liver
4
214
What are lobules of liver made up of?
lobules are made up of cuboidal cells called hepatocytes which are arranged in pairs of columns radiating from a central vein.
215
Between two pairs of columns of cells, what are there in the liver lobules?
Between two pairs of column of cells there are sinusoids (blood vessels with incomplete walls) containing mixture of blood from the tiny branches of the portal vein and hepatic artery.
216
In the lining of the sinusoids, what can be found?
Hepatic macrophages (Kupffer cells)
217
What do canaliculi form after joining up?
Larger bile canals
218
What can be found in the corner of the hexagonal structure?
a branch of hepatic artery a branch of the hepatic portal vein intra lobular bile duct
219
What are the functions of the liver?
food digestion perform functions such as metabolism of carbohydrates, fats and proteins detoxification of drugs and toxic substances defense against microbes, some hormone inactivation heat production.
220
What are the functions of the liver related to digestion?
The liver secretes bile which is stored in the gall bladder until released into the duodenum. The bile contains bile salts which act as emulsifiers that help in fat digestion and absorption. Most of the absorbed nutrients reach the liver and it regulates the distribution of nutrients to the rest of the body. Excess glucose is stored as glycogen in the liver cells. Glycogen deposition and break down in the liver cells are regulated by insulin and glucagon hormones. Fat soluble Vitamins (A,D,E and K) and some water soluble vitamins (B12), iron and copper are also stored in liver. (KADE)
221
What are the two ways of regulation of digestion of man?
1. Nervous regulation 2. Endocrine regulation
222
How does nervous regulation help in regulation digestion in man?
nervous reflex stimulates the release of saliva when food reach the mouth. Arrival of food in the stomach trigger churning and release of gastric juices.
223
How does endocrine system play a role in digestion?
*Endocrine system plays a critical role in digestion especially in the stomach and small intestine. *When food arrives the stomach, the stomach wall is stretched. This triggers to release the hormone gastrin. Gastrin circulates via the blood stream and arrives the stomach. Then gastrin stimulates the production of gastric juice at the stomach.
224
What stimulate the release of cholecystokinin and secretin from duodenum?
Fatty acids and amino acids in the chyme
225
What does cholecystokinin trigger?
Cholecystokinin triggers release of bile from the gall bladder and digestive enzymes from the pancreas
226
What does secretin stimulate?
Secretin stimulates the release of bicarbonate from the pancreas.
227
What is the function of HCO3- in the pancreas?
Bicarbonate neutralize the chyme received from the stomach
228
What happens when the chyme is rich in fat?
Food digestion in the stomach slows down due to high levels of Cholecystokinin and Secretin secreted by duodenum. These hormones act on the stomach and inhibit peristalsis and gastric juice secretion.
229
What are the main components of food in a balanced diert?
*Carbohydrates • Proteins • Lipids • Vitamins • Mineral elements • water • fibers
230
What are the two types of carbohydrates?
*sugars *polysaccharides (in rice and bread)
231
What are the functions of digestible carbohydrates?
*Provide energy and heat: breakdown of carbohydrates provides ATP for body functions and generates heat. * Act as an energy stores. e.g. excess carbohydrates are converted into glycogen and fat * Facilitates protein sparing- proteins are not used to get energy when there is an adequate carbohydrates in the food
232
What are proteins made up of?
Amino acids
233
What happens to proteins during digestion?
proteins are broken down into amino acids absorbed into the blood stream.
234
What are the two types of amino acids?
essential amino acids non essential amino acids
235
What are the functions of proteins in the diet?
• are used for growth and repair of body cells and tissues • are used for synthesis of plasma proteins, enzymes, antibodies and some hormones (pahe) • Act as an energy source for body functions
236
What are lipids made out of?
Fats Oils
237
What are the two types of fats in lipids?
Essential fatty acids Non essential fatty acids
238
What are the functions of lipids in the diet?
• Provide energy and heat (on weight basis fats and oils provide more energy compared to carbohydrates and proteins) • Help in transport and storage of fat soluble vitamins such as Vitamin A, D, E and K • Store energy as fat in the adipose tissues • Help to synthesize steroid hormones from cholesterol. • Provide insulation: (ex. fat found in subcutaneous layer in the skin reduces heat loss , constituents of myelin sheath of neurons)
239
What are the two types vitamins?
fat soluble vitamins (Vitamin A, D, E and K) water soluble vitamins (Vitamin B and C).
240
What is the function of vitamin A?
form visual pigments in the eye epithelial tissue maintenance, promotion of growth and immunity
241
What is the function of vitamin B?
components of coenzymes such as FAD and NAD, promote red blood cell production
242
What is the function of vitamin C?
act as an antioxidant used in collagen synthesis
243
What is the function of vitamin D?
aids in absorption and use of Calcium and Phosphorous
244
What is the function of vitamin E?
act as an antioxidant
245
What is the function of vitamin K?
It is important in blood clotting
246
What is the function of the Ca mineral?
form bones and teeth helps clotting blood nerve and muscle function
247
What are 2 anti oxidants as vitamins?
Vitamin C and vitamin E
248
What are the functions of P mineral?
form bones and teeth help maintain in acid base balance
249
What are the two minerals forming bones and teeth?
Ca and P
250
What is the function of S?
components of some amino acids
251
What is the function of K?
help maintain in acid base balance and water balance nerve function
252
What is the function of Cl?
help maintain in acid base balance maintain osmotic balance nerve function
253
What is the function of Na?
help maintain in acid base balance and water balance nerve function
254
What minerals maintain acid base balance?
Na K cl P
255
What minerals help in water balance?
Na K
256
What is the function of the mineral Mg?
act as enzyme cofactor
257
What is the function of the mineral Fe?
Components of hemoglobin electron carriers act as an enzyme cofactor
258
What is the function of the mineral F?
maintenance of tooth structure
259
What is the function of the mineral I?
component of thyroid hormone
260
What act as enzyme cofactors?
Mg and Fe
261
What are the ways by which water is lost in the human body?
Urine Sweating Feces
262
Why is the amount if water taken into the body balanced?
drinking food
263
What are the functions of water?
• Provides the moist internal environment for all living cells. • Major component of blood and tissue fluid therefore helps to transport materials around the body and to exchange materials between blood and tissues and body cells • Regulate body temperature mainly through evaporative cooling • Dilute waste products and toxins and provide a medium for their excretion • Moisten the food and that make easier to swallow
264
What are fibers made out of?
indigestible polysaccharides
264
What are fibers made out of?
indigestible polysaccharides
264
What are fibers made out of?
indigestible polysaccharides
265
What are the functions of dietary fibers?
• Provide bulk to the diet and satisfy the appetite. • Prevent constipation by attracting water to increase faecal bulk and stimulating peristalsis leading to defecation. • Adequate fibres in the diet protect against some gastro-intestinal disorders such as cancers in the colon and rectum.
266
What are examples of essential nutrients?
essential amino acids, essential fatty acids, vitamins minerals.
267
Why is it essential to intake essential nutrients?
key functions in bio synthetic reaction in the body cells. If these essential nutrients are not supplied in correct proportions in the diet that will lead to malnutrition. Therefore it is essential to obtain them in correct amounts.
268
What are essential amino acid examples?
Leucine and methionine.
269
What does obesity lead to?
Diabetes mellitus cardiovascular diseases some cancers
270
BMI equation?
Mass/ height^2(kg/ m2)
271
What occurs in gastritis?
In gastritis, glands of the stomach wall are stimulated and secrete excess HCl causing damage to the mucosa. Due to the damages of mucosa layer of the stomach, blisters can be formed.
272
What are the reasons for the secretion of HCL?
Prolonged starvation mental stress Some drugs like asprin
273
What bacteria is long lasting bacteria associated with?
Helicobacter pylori
274
What is the reason for gastritis?
prolonged starvation
275
What should be practiced for gastritis?
proper food habits should be practiced
276
What leads to constipation?
Inhibition of the reflex action in defecation
277
What does constipation lead to?
pain in the anus and difficulty in defecating
278
How can constipation controlled by?
by developing behavioral adjustments to carry out defecation properly
279
What can prevent constipation?
Intake of adequate fiber in the diet can help prevent constipation.
280
Describe the need of the circulatory system.
As organisms increase in size and complexity, the amount of materials moving in and out of the body also increases. The distance that materials have to be transported within the body also increases and many cells are not in direct contact with their external environment. Therefore diffusion is not sufficient to transport materials throughout the body. Therefore circulatory systems have evolved
281
Describe why a circulatory system for simple organisms is not needed?
*A circulatory system is required in animals for transportation of materials within the body and exchange of materials with the external environment. *The simple animals (e.g. Cnidarians, Flat worms) lack specialized system for the transport and distribution of material because many or all cells are in direct contact with the external environment.
282
What are the substances that are transported in the body
respiratory gases (oxygen, carbon dioxide) nutrients (glucose, amino acids, fatty acids, vitamins, etc.),-VAGF waste products of metabolism (urea, ammonia, etc) hormones antibodies
283
What are the components of the animal circulatory system
A muscular pumping device (heart), interconnected vessels circulatory fluid (blood/ hemolymph).
284
What are the two types of circulatory systems in animals?
1. Open CVS 2. Closed CVS
284
What are the two types of circulatory systems in animals?
1. Open CVS 2. Closed CVS
285
What are the two groups of animals that have the open cvs?
Mollusca Arthropoda
286
What are the organisms that show closed CVS?
Vertebrates Invertebrates like annelids
287
What are the three main types of blood vessels in CVS?
arteries veins capillaries.
288
What organisms show single circulation?
Bony fishes, Cartilagenous fishes such as rays and sharks.
289
what organisms show double circulation?
Amphibians, Reptiles, Aves, Mammals.
290
Who has three chambers of the heart?
Amphibians and most reptiles
291
What organisms have four chambers of heart?
Birds Mammals
292
What is the difference between double circulation and single circulation?
Double circulation is more effective in supplying blood to all body organs and tissues especially brain and muscles due to the higher pressure exerted by the heart in the systemic circulation. This in contrast to single circulation where blood flows under reduced pressure from the gas exchange organs to other organs.
293
Where does oxygen poor blood drain into?
Oxygen poor blood from trunk and hind limbs is drained into the inferior vena cava and oxygen poor blood from the head, neck and fore limbs are directed into the superior vena cava.
294
Where does the gas exchange occur in the CVS?
capillary beds where O2 rich blood is diffused into the tissues while the CO2 rich blood diffused into the blood capillaries
295
What are the features of the lymphatic system?
The lymphatic system is closely connected with the blood circulatory system both structurally and functionally. It consists of lymph vessels through which lymph travels.
295
What are the features of the lymphatic system?
The lymphatic system is closely connected with the blood circulatory system both structurally and functionally. It consists of lymph vessels through which lymph travels.
296
What does the lymphatic system include?
lymph nodes lymphoid tissues (tonsils) lymphoid organs (e.g. spleen and thymus).
297
What does lymph vessels consist of?
tiny vessels larger vessels.
298
What does lymph vessels consist of?
tiny vessels (Tiny lymph vessels are in close contact with the capillaries of the blood circulatory system) larger vessels.
299
What are lymph nodes composed of?
connective tissues white blood cells.
300
What is the function of the lymphatic system?
returns lost fluid and proteins from the blood capillaries back into the blood tissue drainage to maintain the blood volume in the blood circulatory system - absorption of fat and fat soluble vitamins from the small intestine - for immune responses.
301
What is lymph?
The lost fluid from the blood capillaries is called lymph when they are inside the lymphatic system
302
What is the composition of the lymph?
same as interstitial fluid
303
What is the function of lymph vessel valves?
It prevents the backflow of the lymph
304
What is the function of valves in the lymphatic system?
That prevents the backflow of the lymph.
305
To where is lymph drained into?
The lymph is drained into veins at the base of the neck via two large ducts The rhythmic contraction of the lymph vessel walls and skeletal muscle contraction help to move the lymph.
306
What are the three layers of tissues heart wall is composed of?
Pericardium Myocardium Endocardium
307
What are the two sacs which the pericardium is made out of?
outer fibrous pericardium inner serous pericardium.
308
What is the special feature of myocardium?
It is composed of specialized cardiac muscle found only in the heart
309
What are the four chambers of the human circulatory system?
Two ventricles Two atria
310
What takes place during the pulmonary circulatory system?
takes oxygen poor blood to the respiratory surface, the lungs and returns the oxygen enriched blood back to the heart
311
What are the two different types of circulatory systrmd
Pulmonary circuit Systemic circuit
312
By what is the heart completely divided into right and left sides?
By septum
313
By what is the atrium and ventricle divided by?
AV valve
314
How many flaps does the right AV valve have?
3 flaps
315
How many flaps does the left ventricular valve has?
2 flaps
316
What are the extensions of the inner wall of ventricles?
papillary muscles
317
What is the function of chordae tendinea?
prevents the valves from being turned inside out
318
Where can we find semilunar valves?
found at the points where the pulmonary artery and aorta leave the right and left ventricles respectively.
319
What is the function of semi lunar valves?
These valves prevent the backflow of blood into the ventricles.
320
From where does the pulmonary arteries with oxygen poor blood leave from?
Two pulmonary arteries with oxygen poor blood leave the heart from the upper part of the right ventricle
321
To where does pulmonary veins give blood to?
Two pulmonary veins from each lung carry oxygen rich blood back to the left atrium.
322
Where does the aorta leaves from?
The aorta with oxygen rich blood leaves from the upper part of the left ventricles.
323
Where does the aorta leave from in the CVS?
The aorta with oxygen rich blood leaves from the upper part of the left ventricles.
324
What does the superior and the inferior vena cava open into?
The superior vena cava and inferior vena cava open into the right atrium and empty their contents into the right atrium
325
By what blood supply is the heart supplied with?
The heart is supplied with arterial blood by the right and left coronary arteries
326
From what does the left and right coronary arteries branch from?
the aorta immediately after the aortic valve
327
By what nerve fibers is the heart supplied with?
both sympathetic and parasympathetic nerve fibers
328
What two hormones does the heart respond to?
adrenaline and thyroxine
329
What initiate and conduct impulses?
Small group of specialized neuromuscular cells in the myocardium
330
What does the conducting system of the heart consists of?
• SA node (Sinoatrial node) • AV node (Atrioventricular node) • Atrioventricular bundle (bundle of His), bundle branches and Purkinje fibres
331
What happens in the SA node? What is the function?
The stimulus for contraction of the heart originates in the ‘SA node’. The SA node initiates the heart beat and sets the rhythm of the heart beat so it is called the pace maker.
332
What is the location of the SA node?
It lies in the myocardium of the right atrium near the opening of the superior vena cava
333
How can the heart rate be varied?
by the stimulation from the autonomic nervous system, hormones such as adrenaline, thyroxine temperature.
334
Where is the AV node located in?
between wall of the left and right atria
335
What is the function of AV node?
transmits the electrical signals from the atria into the ventricles
336
Where does the AV bundle originate from?
from the AV node
337
What does the AV bundle cross?
fibrous rings that separate atria and ventricle at the upper end of the ventricular septum
338
What is the function of the purkinje fibers and bundle branches?
transmit electrical impulse from the AV node to the apex of the myocardium. As a result of this impulse, wave of ventricular contractions begin. Then the contraction sweeps upwards and outwards pumping blood simultaneously into the pulmonary artery and the aorta.
339
What does the cardiac cycle involve?
1. Atrial systole – Contraction of the atria 2. Ventricular systole - Contraction of the ventricles 3. Complete cardiac diastole – Relaxation of the atria and ventricles
340
What transports poor oxygen blood :( to right atrium?
The superior vena cava the inferior vena cava
341
What brings oxygen rich blood to the left atrium?
4 pulmonary veins
342
What triggers a wave of contractions that spread across the myocardium of both atrium?
SA node
343
To where are the electrical impulses generated by the AV node spread to?
the ventricular muscles via the AV bundle the bundle branches, and Purkinje fibers
344
How is it ensured that blood only flows in one direction in the body?
The sequence of opening and closing of valves ensure that blood flows only in one direction.
345
What does an ECG indicate?
the spread of the electrical signal generated by the SA node as it travels throughout the heart.
346
What does the P wave represent in an ECG?
It represents the impulse from the SA node as it sweeps over the atria (atrial depolarization).
347
What does QRS wave complex represent?
It represents rapid spread of impulse from the AV node throughout the ventricles and electrical activity of the ventricular muscles.( ventricular depolarization)
348
What does the T wave represent in an ECG?
Represents ventricular repolarization and relaxation of the ventricular muscles.
349
Due to a larger QRS complex, what cannot be seen?
atrial repolarization which occurs during ventricular contraction
350
what can be obtained by examining the pattern of waves and the time interval between cycles and parts of cycles?
Information about the heart function of a person ( state of the myocardium and the cardiac conduction system)
351
What does blood pressure in the arteries of systemic circulation maintain?
the essential flow of blood into and out of the organs of the body
352
Why is it important to keep the blood pressure in normal limits?
High blood pressure could lead to damage blood vessels resulting in formation of clots or bleeding from damaged sites. If the blood pressure falls too low, there will be inadequate blood flow through tissue capillary beds. This will adversely affects the normal functioning of vital organs such as the brain, heart and kidneys.
353
What does the blood pressure vary according to?
according to: the time of day the posture gender age activity exercise stress (Emotional states) of an individual
354
When does blood pressure drop?
Blood pressure falls at rest and during sleep
355
When does blood pressure rise?
Blood pressure increases during excitement, fear or anxiety
356
By what equipment is atrial blood pressure measured?
sphygmomanometer
357
What is the equation for atrial blood pressure?
Systolic pressure (mm Hg) / Diastobic pressure (mm Hg)
358
What are the consequences of hypertension?
kidney damage adrenal gland disorders heart attack (because of the increased heart rate and cardiac contraction) stroke(caused by cerebral hemorrhage) damaged blood vessels which can lead to death
359
What are the risk factors for hypotension?
• Obesity • Diabetes mellitus • Family history • Smoking • A sedentary life style • High intake of salts • High intake of alcohol • Stress • Deposition of low density lipoprotein (LDL) on artery walls
360
What is hypotension as a result of?
shock dengue hemorrhage fever standing up suddenly from sitting or lying position over bleeding/ hemorrhage condition fasting low nutrition
361
What does low blood pressure lead to?
inadequate blood supply to the brain depending on the cause unconsciousness may be brief (fainting) or prolonged possibly causing death
362
What are the consequences of the blockage of coronary arteries?
Atherosclerosis -> Thrombosis -> heart muscle will be deprived of oxygen and nutrients -> chest pain (angina) -> myocardial infarction
363
Depending on what conditions will the heart muscle be deprived of oxygen and nutrients?
Depending on the place (s) of the block in the coronary arteries and the degree of blockage related parts of the heart muscle
364
What are the results of myocardial infarction?
364
What are the results of myocardial infarction?
365
What are the results of myocardial infarction?
Heart beat rhythm may be abnormal and the heart may cease to be an effective pump. The other vital organs such as brain may be deprived of inadequate supply of oxygen rich blood and heart attack may be fatal if not treated on time.
366
Why are respiratory pigments necessary?
Since oxygen is less soluble in watery medium including blood, transportation of oxygen from respiratory surface to the tissues/ organs is a problem for complex animals
367
What organisms use hemoglobin as the respiratory pigment?
Present in blood of human, other vertebrate and annelids
368
What organisms use Haemocyanin as the respiratory pigment?
present in hemolymph of arthropods and molluscs.
369
What organisms use Chlorocruorin as a respiratory pigment?
present in the blood of many annelids
370
What organisms use Haemoerythrin as the respiratory pigment?
present in the blood of marine invertebrates (some annelids)
371
What organisms use myoglobin as a respiratory pigment?
present in vertebrate muscles
372
What are the respiratory pigments seen in annelids?
Haemoglobin Chlorocruorin Haemoerythrin
373
What are the respiratory pigments seen in vertebrates?
Haemoglobin Myoglobin
374
What are the functions of the respiratory pigments except myoglobin?
transport oxygen from respiratory surfaces to the tissues and organs while transporting carbon dioxide from tissue/ organs to the respiratory surface for elimination
374
What are the functions of the respiratory pigments except myoglobin?
transport oxygen from respiratory surfaces to the tissues and organs while transporting carbon dioxide from tissue/ organs to the respiratory surface for elimination
375
What is the function of the myoglobin respiratory pigment?
oxygen storage function
376
What is hemoglobin composed of?
globin protein haem group
377
Where can the hemoglobin molecule found in?
Erythrocytes
378
What is the function of hemoglobin molecule?
responsible for the transport of oxygen around the body
379
What is responsible for the characteristic red colour of the blood of the hemoglobin molecule?
Haem groups
380
What combine reversibly with one molecule of oxygen?
A ferrous(iron) atom each hemoglobin molecule can carry up to four oxygen molecules.
381
Explain the equation for the formation of Combination of oxygen with hemoglobin to from oxyhemoglobin
Hb + 4O2 ========> HbO8 (Hemoglobin molecules)
382
What are the different ways of transportation of CO2 in the blood
• As HCO3- ions in the plasma (about 70%): When CO2 diffuses into the red blood cells the enzyme carbonic anhydrase catalyze the combination of CO2 with water to form bicarbonate ( HCO3- ) and H+ ions. The HCO3- moves out of the erythrocytes into the plasma • As carbaminohemoglobin (about 23%): CO2 combined with protein group of hemoglobin and form carbaminohemoglobin. Therefore CO2 does not compete with oxygen binding sites in hemoglobin. • Dissolved in plasma (about 7%): as free gas.
383
What are the cellular components of blood?
red blood cells white blood cells platelets
384
What are Red blood cells, leukocytes and platelets developed from?
bone marrow in the bones such as (vpsr) ribs, vertebrae, sternum pelvis
385
What does the erythropoietin hormone stimulate?
Erythropoietin hormone (from kidneys) stimulates the generation of red blood cells
386
What is cells composed of?
cells plasma
387
What is the shape of the RBC?
small biconcave disk-like cells
388
What do mature erythrocytes lack?
Nuclei
389
What is the advantage of mature erythrocytes lacking nuclei?
This character helps to carry more hemoglobin molecules within the cell
390
RBC lack mitochondria. Then, how do they produce ATP?
via anaerobic respiration. If they produce ATP by aerobic respiration that will reduce the O2 transport efficiency
391
Depending on what factors do the number of RBC vary?
gender health status.
392
What is the main function of RBC?
Transportation of O2 molecules. They also transport CO2 molecules.
393
What are the five types of leukocytes?
Basophils, Lymphocytes, Eosinophils, Neutrophils and monocytes (NEVER LET MONKEYS EAT BANANAS)
394
What are the main functions of leukocytes
body defense phagocytic engulfing digesting microorganisms increase immune response against foreign substances.
395
What do lymphocytes develop into?
T cells B cells
396
Where are platelets developed from?
Bone marrow
397
Do platelets have nuclei?
No
398
What is the function of platelets?
play a major role in blood clotting
399
What is the Ph of blood?
Around 7.4
400
Where can we find a high protein concentration?
in plasma (higher than in interstitial fluid)
401
What is the function of dissolved ions in the plasma?
buffer and maintain the osmotic balance in the blood
402
What is the function of albumin in the blood plasma?
buffers the blood
403
What is the function of antibodies?
Involved in defense
404
What is the function of fibrinogen?
aids in blood clotting
405
What is blood called when all the clotting factors are removed?
serum
406
What are the main functions of the blood?
• Transport of oxygen to organs and removal of carbon dioxide from the organs and tissues • Transport of soluble excretory materials to organs of excretion • Transport of nutrients • Transport of hormones from the glands where they are produced to target organs • Defense against foreign invasions • Aids in osmoregulation
407
What is the function of the blood clot?
This prevents further blood loss This prevents the entry of pathogenic micro organisms which is of clear survival value
408
What happens when a blood vessel is damaged?
When the blood vessel is damaged the connective tissues of the vessel wall is exposed. Therefore platelets in the blood adhere to the collagen fibers in the connective tissue and release substance that makes close by platelets sticky, forming a platelet plug.
409
What is the function of the platelet plug during blood clotting?
provides instant protection against blood loss
410
What takes place after the platelets release clotting factors?
They trigger the formation of thrombin. Then thrombin converts fibrinogen into fi brin. Next this fi brin aggregates into threads that form a network of the clot. The activated thrombin is also involved in formation of more thrombin which completes the formation of blood clot.
411
What are examples for pressure receptors?
Pacinian corpuscles which are present in the deep skin. They are sensitive to deep pressure.
412
Examples for vibration corpuscles?
Meissner corpuscles, Pacinian corpuscles) Specific hair cells in the organ of Corti in the inner ear detect sound vibrations. Hair cells of the vestibule of the inner ear detect the gravity whereas hair cells of the semicircular canals detect the motion
413
What kind of stimuli do the pain receptors detect?
reflect harmful conditions that could arise from extreme pressure or temperature and certain chemicals that could damage the tissues.
414
Examples of pain receptors?
Special nerve endings in different parts of the body can detect the tissue damage. Ultimately the pain is perceived by the brain.
415
Three layers of tissues of the eye wall?
The outer fibrous layer (sclera and cornea), the middle vascular layer (choroid, cilliary body and iris) and the inner nervous layer (Retina)
416
What does the eye ball contain?
lens, aqueous fluid and vitreous body.
417
What is the structure of the sclera?
Sclera is white and opaque. It is the outermost layer of the posterior and lateral aspects of the eye ball. It connects anteriorly with the clear transparent epithelial membrane called cornea.
418
What is the function of the sclera?
Sclera maintains the shape of the eye and gives attachment of the extrinsic muscles of the eye.
419
Describe the structure of the cornea?
Cornea is the passage through which light rays reach the retina. It is devoid of blood vessels. The cornea is convex anteriorly
420
What is the function of the cornea?
involved in refracting light rays to focus on the retina.
421
Describe the structure and the location of the choroid layer?
Choroid is located just beneath the sclera. It is a thin pigmented layer and rich with blood vessels.
422
What is the structure of the ciliary body?
Cilliary body is the anterior continuation of the choroid layer consisting of smooth muscle fibers (ciliary muscle) and sensory epithelial cells. Most of these smooth muscle fibers are circular.
423
What is the function of the ciliary body?
ciliary muscles act as a sphincter. The ciliary body holds the lens in place by suspensory ligaments
424
What is the function of the ciliary muscle fibers?
The size and thickness of the lens can be controlled by contraction and relaxation of the ciliary muscle fibers attached to these suspensory ligaments
425
What do the epithelial cells of aq humour secrete?
Epithelial cells secrete aqueous humor
426
Describe the structure of the iris
Iris is a circular coloured body composed of pigment cells. It is located at the front of the eye. It extends anteriorly from the ciliary body and present behind the cornea and in front of the lens
427
What does the iris contain?
two layers of smooth muscle fibers which are arranged as circular and radial bundles. In the center of iris is a hole called pupil.
428
What is the function of the iris?
Iris controls amount of light entering the pupil by changing size which is mediated by the autonomic nervous system. Pigments prevent penetration of excessive light.
429
What is the location of the lens?
The lens is lying immediately behind the pupil.
430
Describe the structure of the lens?
It is an elastic, biconvex transparent disc made up of protein enclosed within a transparent capsule.
431
What is the function of the lens?
It refracts light rays reflected by objects in front of the eye and focuses them on the retina to form the image. By changing the thickness, the lens can vary its refractive power in order to focus rays on the retina.
432
What is the function of the aq fluid?
Aqueous fluid supplies nutrients and removes wastes from the cornea, lens and lens capsule which have no blood supply. (Blockage of ducts that drain this fluid can produce glaucoma causing vision loss) :(
433
What is the location of the vitreous body?
Behind the lens a colourless and transparent jelly like vitreous humour is present.
434
What is the location of the vitreous body?
Behind the lens a colourless and transparent jelly like vitreous humour is present.
435
What is the function of the vitreous body?
It maintains enough intra ocular pressure to support the retina against choroid and prevents the eye ball from collapsing.
436
What are the three layers of the retina?
Outer pigmented epithelium middle photoreceptive layer inner layer with neurons
437
What does the photoreceptive layer contain?
sensory cells (rods and cones) which contain photosensory pigments that can convert light rays into nerve impulses.
438
describe the structure of the retina
Retina is thickest at the back. At the centre of the posterior part of the retina, macula lutea (yellow spot) is present. In the center of the yellow spot there is a little depression called the fovea centralis which contains only cones. Towards the anterior part of the retina there are fewer cones than rods. About 0.5 cm to the nasal side of the macula lutea all the nerve fibers of the retina converge to form the optic nerve. The small area of retina where the optic nerve leaves eye is the blind spot (optic disk). It lacks photoreceptors.
439
Function of rhodopsin?
In the rods visual pigment is rhodopsin. They are sensitive to light but do not distinguish colours. They enable us to see at night but only in black and white.
440
Function of photopsin?
visual pigment is photopsin. They provide colour vision. They contribute very little to night vision as they are less sensitive.
441
What is the function of cones?
There are three types of cones each of which has a diff erent sensitivity across the visible spectrum providing an optimal response to red, green or blue light.
442
What do the neurons in the retina contain?
bipolar cells and ganglion cells.
443
What is the pathway of refraction of the light rays?
Light rays coming from the visual fi eld pass through the conjunctiva fi rst, then successively through cornea, aqueous fl uid, lens and vitreous body before reaching the retina
444
What structures of the eye have 1. constant refractive power 2. changing refractive power?
Lens has changing refractory power while all the other parts (conjunctiva, cornea, aqueous fluid and vitreous body) have constant refractory powers. Light rays are mostly refracted by the biconvex lens.
445
What is the size of the pupil controlled by?
autonomic nervous system
446
What are the three main adjustments of the eye?
Constriction of the pupil Movement of the eye ball (convergence) Changing the refractory power of the lens
447
What is the difference between the monocular and binocular vision?
Monocular vision: it is possible to see visual fi elds with one eye. Seeing the visual field using only one eye is called monocular vision Binocular vision: Seeing the visual field using two eyes with greater overlapping fields of view is called binocular vision. *The left eye views more on the left of the visual fields. *The right eye views more on the right of the visual fields. Even though each eye views a scene from a slightly different angle, in the middle the visual fields are overlapped. *However only one image is perceived due to the fusion of left, middle and right of the visual field images from the two eyes in the occipital lobe of the cerebrum.
448
What is the disadvantage of monocular vision?
However when one eye is used, three dimensional vision is impaired especially in relation to the judgment of speed and distance.
449
What are the advantages of the binocular vision?
Unlike monocular vision, binocular vision enables three dimensional views. * So binocular vision is very important in judging the speed and distance of an approaching object such as a vehicle. *It gives more accurate assessment of one object relative to another in relation to distance, depth, height and width. *In some individuals, binocular vision may be impaired. Such individuals face difficulties to judge the speed and distance of an approaching object
450
What is the three parts of the human ear?
outer ear middle ear inner ear.
451
Function of the semicircular canals?
Semicircular canals and vestibule located in the inner ear provide information about the position of the head in space and contribute to maintain the posture and balance. Utricle and saccule of the vestibule perceive position with respect to gravity or linear movements.
452
Function of the semicircular canals?
*Semicircular canals and vestibule located in the inner ear provide information about the position of the head in space and contribute to maintain the posture and balance. *Utricle and saccule of the vestibule perceive position with respect to gravity or linear movements.
453
What are the areas subjected to wear and tear?
palms and fingers of the hand, sole of the foot
454
Describe about the function of melanin?
a dark pigment called melanin contribute to the skin colour.
455
What can affect the skin colour?
Circulating blood in the dermis, excessive levels of bile pigments and carotenes in the fat layer
456
What are the main cells of the dermis?
Fibroblasts, macrophages and mast cells
457
What are the structures present in the dermis?
blood and lymph vessels sensory nerve endings sweat glands sebaceous glands hair, arrector pili muscles sensory receptors (Meissner’s corpuscle, Pacinian corpuscle, free nerve endings, bulb of Krause, organ of Ruffini, Merkle discs)
458
What are the functions of the skin?
1. protection 2. regulation of the body temperature 3. cutaneous sensation 4. Synthesis of vitamin D 5. Excretion
459
What are the endocrine glands of the human body?
hypothalamus, pituitary gland, thyroid gland, parathyroid glands, adrenal glands, islets of Langerhans (in the pancreas), gonads, thymus gland and pineal gland
460
What are the isolated endocrine cells?
in some organs and tissues (e.g. stomach, small intestine, kidneys etc.) which secrete specific hormones (e.g. isolated endocrine cells in the stomach secrete the hormone, gastrin).
461
What are the hormones that are produces and released by the hypothalamus?
(five releasing hormones and two release inhibiting hormones), act on the anterior pituitary (target site)
462
What are the hormones produced by the hypothalamus?
(oxytocin and antidiuretic hormone) are stored in the posterior pituitary until they are released into the bloodstream and act on specific target sites.
463
Function of GHRH
Stimulates the secretion of growth hormone (GH) from anterior pituitary
464
Function of TRH
Stimulates the secretion of thyroid stimulating hormone (TSH) from anterior pituitary
465
CRH function
Stimulates the secretion of adrenocorticotropic hormone (ACTH) from anterior pituitary
466
GnRH function
Stimulates the secretion of follicle stimulating hormone (FSH) and luteinizing hormone (LH) from anterior pituitary
467
PRH function
Stimulates the secretion of prolactin hormone from anterior pituitary
468
PIH and GHRIH function?
Inhibits the secretion of prolactin hormone from anterior pituitary Inhibits the secretion of GH and TSH from the anterior pituitary
468
PIH and GHRIH function?
Inhibits the secretion of prolactin hormone from anterior pituitary Inhibits the secretion of GH and TSH from the anterior pituitary
469
Tropic hormones?
TSH, ACTH, FSH and LH
470
non tropic effect hormone?
prolactin he hormone prolactin which is secreted by the anterior pituitary is not a tropic hormone as its target sites are non-endocrine tissues. Prolactin promotes only non-tropic effects.
471
GH function target site
Growth hormone (GH) secreted by the anterior pituitary has a “tropic as well as non-tropic eff ects” as its target sites can be endocrine cells as well as non- endocrine cells. GH is the most abundant hormone synthesized by the anterior pituitary. All body cells
472
TSH function target site
Stimulates secretion of thyroid hormones (triiodothyronine and thyroxin); Stimulates growth of thyroid gland Thyroid
473
Prolactin function target site
Mammary gland Stimulates milk production; Together with other hormones promotes milk secretion by the mammary glands.
474
Follicle stimulating hormone (FSH)
Ovary Ovulation; promote formation of corpus luteum in the ovary (structure formed after ovulation) and stimulates progesterone hormone secretion by the corpus luteum. Testis Stimulate spermatogenesis
475
LH
ovary: Ovulation; promote formation of corpus luteum in the ovary (structure formed after ovulation) and stimulates progesterone hormone secretion by the corpus luteum Testis Stimulates secretion of testosterone hormone
476
How does the posterior connect with the hypothalamus?
The posterior pituitary which is an extension of the hypothalamus connecting via axons, does not synthesize hormones but secretes two hypothalamic hormones (oxytocin and antidiuretic hormone) to the bloodstream
477
ADH function and target site?
Distal convoluted tubules of the nephrons and collecting ducts in the kidney Stimulates resorption of water by increasing permeability to water
478
What is the function of oxytocin hormone and the target site?
Mammary gland Stimulates milk ejection by stimulating contraction of smooth muscles Uterine muscles Promotes parturition by contraction of smooth muscles
479
Thyroid gland functions and location
help maintain normal blood pressure, heart rate and muscle tone and regulate digestive and reproductive functions. also help maintain normal blood pressure, heart rate and muscle tone and regulate digestive and reproductive functions Thyroid gland is located in the neck just below the larynx and in front of the trachea (T3 and T4 proteins)
480
Calcitonin function?
Calcitonin is another hormone secreted by the thyroid gland. Calcitonin helps to lower blood calcium ion level if it is raised above the normal limit. This hormone acts on bone cells and promotes storage of calcium within bone tissues. The hormone also acts on kidney tubules and inhibit calcium reabsorption enhancing calcium excretion.
481
parathyroid gland location
Parathyroid glands (a set four small glands) are embedded in the posterior surface of the thyroid gland located in the neck
482
Parathyroid glabd funtion
Main function of the PTH is to promote high calcium levels in the blood by stimulating calcium reabsorption from the kidney tubules and calcium absorption through the small intestine. If these sources supply inadequate calcium, PTH acts on bone destroying cells and promotes release of calcium from the bones into the blood. PTH has the opposite effect of calcitonin hormone (released by the thyroid gland) on the blood calcium level.
483
Thymus gland location
Thymus gland is located in the upper part of the chest, directly behind the sternum and between the lungs.
484
Thymosin function?
Thymosin acts on the lymphocytes (originated from the stem cells in the bone marrow) and regulates development and maturation of T lymphocytes which are important components of specifi c immunity.
485
Pineal gland location
Melatonin secreted by the pineal gland is involved in the regulation of biological rhythms related to reproduction and daily activity levels. Melatonin seems to be associated with coordination of circadian and diurnal rhythms of many tissues and inhibition of growth and development of sex organs before puberty.
486
Adrenal gland location
Adrenal glands are paired structures, one of which lies superior to each kidney. Each gland is consists of two parts: adrenal cortex (outer) and adrenal medulla (inner).
487
Adrenal gland function
The structure and functions of these two parts are diff erent. Hormones secreted by the adrenal cortex and the adrenal medulla can mediate the stress responses in the body.
488
Hormones of the adrenal cortex?
glucocorticoids and mineralocorticoids.
489
aldesterone function?
maintaining water and electrolyte balance. stimulates the reabsorption of sodium ions by the kidney tubules and excretion of potassium ions in the urine. As sodium reabsorption is accompanied by the water retention, blood volume and blood pressure can be increased. Hence aldosterone hormone is also involved in the regulation of blood volume and blood pressure.