1

Question 1

Next gen sequencing

Answer 1

Cyclic reversible termination
Single nucleotide addition
Real time sequencing
Sequencing by ligation

Question 2

One step catastrophic leading to massive genomic rearrangement

Answer 2

Chromothripsis first observed in CLL
2-3%
Cancers
Bone ca

Question 3

HPT JT SYNDROME

Answer 3

pth ca 15%
94% single gland disease
All glands at equal risk
AD

Question 4

Germ cell tumor

Answer 4

Benign- 60%adults 70%children
20-40 yrs malignant gct
35%- primary pure mediastinal mgc
90% malig tumor occurs in men

Question 5

How many yrs asbestos exposure before mesothelioma

Answer 5

25-40 yrs
Seen in males50-70 yrs
M>f

Question 6

Shoulder resection
Types
Whats classica tikhoff linberg resection

Answer 6

Type1-intraarticular proximal humeral resection
2-partial scapular resection
3- intraarticular total scapulectomy
4-extraarticular total scapulectomy and humeral head resectio( tikhoff linberg)

Question 7

Shin classification

Answer 7

Tracheal involvement in thy ca
1- adjacent-perilaryngeotracheal
2-superficial- invasion of cartilage
3- deep- intercartilagenous space or mucosa without intraluminal
4-intraluminal

Question 8

Fuhrman grading 1-4

Answer 8

Nuclear shape
Diameter
And nucleoli

Question 9

Foster kennedy syndrome

Answer 9

Anosmia
Il optic atrophy
Cl papiledema
Anterior slull base tumr

Question 10

Gerstmann syndrome

Answer 10

Acalculia agraphia l r disorientation finger agnosia

Dominant pareital hemisphere