1

Question 1

aminoglycoside coverage (general)

Answer 1

Gentamicin synergistically with beta lactams or vanco for gram positive; staph and enterococcus. Mainly gram negative; pseudomonas. Monotherapy uncommon.

Question 2

aminoglycoside with: broadest spectrum of activity

Answer 2

amikacin

Question 3

T/F: AGS have anaerobes in their spectrum

Answer 3

false

Question 4

T/F: penicillins have atypicals in their spectrum

Answer 4

false

Question 5

penicillins with: activity against enterococci (gram positive short chain)

Answer 5

ampicillin, amoxicillin, piperacillin

Question 6

penicillins with: activity against MSSA

Answer 6

nafcillin, oxacillin

Question 7

penicillins with: improved gram negative coverage

Answer 7

piperacillin (ticarcillin but nobody uses it)

Question 8

penicillins with: pseudomonal coverage

Answer 8

piperacillin

Question 9

penicillins coverage (general)

Answer 9

Mainly gram positive cocci. Some gram negative rods.

Question 10

penicillins with: anaerobic coverage

Answer 10

amox+clav, pip+tazo, amp+sulbac

Question 11

T/F: Penicillins can be used to treat bacteriodes, haemophilius, and neisseria

Answer 11

True if combined with clavulanate, sulbactam, or tazobactam

Question 12

DOC penicillin for: IE, AOM, h.pylori

Answer 12

amoxicillin

Question 13

T/F: early generation cephalosporins have improved best gram negative coverage

Answer 13

false. early=better gram positive

Question 14

cephalosporins coverage (general)

Answer 14

tricked ya depends on generations mostly

Question 15

cephalosporin generation with: HNPEK coverage

Answer 15

2nd generation

Question 16

cephalosporin generation with: PEK coverage

Answer 16

1st generations

Question 17

cephalosporin generation with: HNPEKS coverage

Answer 17

3rd generation

Question 18

cephalosporin generation with: HNPEKS and CAPES coverage

Answer 18

4th generation

Question 19

bacteria covered in: PEK regimen

Answer 19

*proteus mirabilis, e.coli, klebsiella.

[*oxidase-negative]

Question 20

bacteria covered in: HNPEKS regimen

Answer 20

PEK+ *haemophilus, *neisseria, serratia

[*fastidious; ox-negative]

Question 21

bacteria covered in: CAPES regimen

Answer 21

citrobacter, enterobacter, pseudomonas, acintobacter, serratia [GNR of all categories except fastidious]

Question 22

notable ceftazidime coverage

Answer 22

improved gram negative including pseudomonas. less gram positive.

Question 23

cephalosporin generation with: best gram positive coverage

Answer 23

5th generation; ceftaroline

Question 24

cephalosporin generation with: best gram negative coverage

Answer 24

4th generation; cefepime

Question 25

two ceph generations with: ~equal gram positive activity, but varying negative activity

Answer 25

3rd & 4th generation

Question 26

cephalosporin generation with: lower staph & higher step activity

Answer 26

2nd & 3rd generation

Question 27

cephalosporin generation with: higher staph & lower strep activity

Answer 27

1st generation

Question 28

only two cephalosporins with: anaerobic coverage (bacteriodes)

Answer 28

ceFOXitin, cefoTETan. Lose some positive coverage.

Question 29

cephalosporin generation with: gram positive activity similar to 3rd generation but improved gram negative

Answer 29

4th generation; cefepime

Question 30

cephalosporin generation with: MRSA but no pseudomonas coverage

Answer 30

5th generation; ceftaroline

Question 31

cephalosporins with: pseudomonas coverage

Answer 31

cefTAZidime, ceFEPime

Question 32

carbapenems coverage (general)

Answer 32

very broad: positive, negative, anaerobic.

Question 33

5 notable gaps in carbapenem coverage

Answer 33

atypicals, MRSA, VRE, c. diff, stentotrophomonas

Question 34

T/F: carbapenems cover includes pseudomonas and acintobacter

Answer 34

False, not all! Etrapenem does not

Question 35

carbapenem that is not indicated for HAP, VAP, or lung infections

Answer 35

doripenem

Question 36

carbapenem that is given with cilastatin to prevent dihydropeptidase in the normal kidney from breaking it down

Answer 36

imipenem

Question 37

FQs coverage (general)

Answer 37

extensive activity: positive, negative, and average-to-excellent atypical (except ciprofloxacin)

Question 38

FQs with: pseudomonas & enhanced gram negative coverage

Answer 38

ciprofloxacin, levofloxacin

Question 39

FQs with: anaerobic & enhanced gram positive coverage

Answer 39

moxifloxacin

Question 40

respiratory fluoroquinolones

Answer 40

gemifloxacin, levofloxacin, moxifloxacin

Question 41

FQs with: common mixed infections/IAI monotherapy use

Answer 41

moxifloxacin

Question 42

FQs with: enahnced strep. pneumo and & atypical coverage

Answer 42

gemifloxacin, levofloxacin, moxifloxacin

Question 43

treating pseudomonas with FQs

Answer 43

usually requires combo therapy (beta-lactam typical)