1/8 Weller Intro to Virology Flashcards Preview

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Flashcards in 1/8 Weller Intro to Virology Deck (30):
1

What category of microorganisms are obligate intracellular parasites?

Viruses

2

Types of capsid structure
3

Helical
Icosahedral
Complex (spider looking thing)

3

VIral components
2

Protein covering
Genetic material

4

TYpes of protein covering
2

Envelope
Capsid

5

Types of genome in virus

Group 1
2
3
4
5

6

Group 1

1) DNA +/-
2) mRNA

7

Group 2

1) DNA +
2) DNA +/-
3) mRNA

8

Group 3

1) RNA +/-
2) mRNA

9

Group 4

1) RNA +
2) RNA -
3) mRNA

10

Group 5

1) RNA -
2) mRNA

11

Group 6

1) RNA +
2) RT
3) mRNA

12

Group 7

1) DNA +/-
2) RT
3) mRNA

13

Viral genome types of structure of genome

Linear
Circular
Segmented
Gapped

14

Viral life cycle

Attachment
Entry
Penetration

15

What is the period when the virus is inside the host cell and off the radar of immune system called?

Eclipse face

16

TYpes of enveloped penetration

Fusion
Viropexis (vesicle goes in)

17

How does capsid penetration happen?

Clathrin - mediated endocytosis

18

Susceptibility def

Whether cell has receptors for virus to gain entry

19

Permissivity

Whether cell has machinery to support virus

20

Resistant def

CEll is missing either receptors or machinery or both

21

Cell must be what in order to become infected by virus

susceptible and permissive

22

For DNA viruses, if replication occurs in cytoplasm, then what?

All replication machinery will have to be provided by virus

23

Does +RNA enter the nucleus?

no need

24

-RNA brings what into a cell and why?

RNA reverse polymerase to make complimentary +RNA

25

-RNA replicates in nucleus or cytoplasm?

Either

26

Retrovirus def

RNA viruses that reprodue through DNA intermediate

27

Reverse Transcriptase def

Enzymes capable of making DNA from RNA.
DNA then is integrated into host DNA

28

How is the virus assembled?

In a way to favor incorporation of viral genomes

29

WHat has an impact on mutation rate

Genome Size
Replication Rate
host COnditions

30

In regards to mutation, what has the highest rate of mutation

Smaller size