1: Combined Contraceptive Hormone Generations Flashcards

1
Q

What generation? Progestin norethynodrel

A

1st

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2
Q

What generation? Progestin norethindrone

A

1st

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3
Q

What generation? Progestin norethindrone acetate

A

1st

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4
Q

What generation? Progestin ethynodiol diacetate

A

1st

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5
Q

What generation?

  • Well tolerated
  • Found in many generic formulations and some low-dose brand-name COCs
  • Unscheduled bleeding/spotting at lower doses
A

1st

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6
Q

What generation? Progestin norgestrel

A

2nd

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7
Q

What generation? Progestin levonorgestrel

A

2nd

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8
Q

What generation?

  • Potent with long half-life
  • Increase in androgen-related side effects (adverse effects on lipids, oily skin, acne, facial hair)
A

2nd

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9
Q

What generation? Progestin desogestrel

A

3rd

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10
Q

What generation? Progestin norgestimate)

A

3rd

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11
Q

What generation?

  • Reduced androgenic SEs
  • Fuller impact of estrogen which may increase risk of thromboembolism
A

3rd

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12
Q

What generation?

  • Antimineralcorticoid and antiandrogenic properties
  • Tx of PMDD and acne
  • No increased risk of thromboembolism
A

4th

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13
Q

What generation? Progestin drospirenone

A

4th

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14
Q

What generation?

More profound, diverse, and discreet endometrial effect compared to others (progestin).

A

Next Generation

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15
Q

What generation of estrogen?

  • Availability: 20, 25, 30, 35, 50 mcg and one preparation containing 10mcg
A

Next Generation

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16
Q

What generation? Progestin dienogestrel

A

Next Generation

17
Q

What generation? Estrogen ethinyl estradiol (EE)

A

Next Generation

18
Q

Name the 1st generation progestins (4).

A
  • Norethynodrel
  • Norethindrone
  • Norethindrone acetate
  • Ethynodiol diacetate
19
Q

Name the 2nd generation progestins (2).

A
  • Norgestrel
  • Levonorgestrel
20
Q

Name the 3rd generation progestins (2).

A
  • Desogestrel
  • Norgestimate
21
Q

Name the 4th generation progestin (1).

A

Drospirenone

22
Q

Name the next generation hormones (2).

A
  • Progestin: dienogestrel
  • Estrogen: ethinyl estradiol
23
Q

Which generation would you avoid for someone with acne or facial hair growth?

A

2nd generation

24
Q

Which generation has more spotting and unscheduled bleeding at lower doses?

A

1st generation

25
Q

Which generation has a lesser androgenic effects, but more estrogenic effects leading to a possible increased risk for venous thromboembolism?

A

3rd generation

26
Q

Which generation is best for treatment of acne and PMDD?

A

4th generation

27
Q

Which generation has more profound, discreet, and diverse endometrial effects compared to other progestins?

A

Next generation