1: Combined Contraceptive Hormone Generations

Question 1

What generation? Progestin norethynodrel

Answer 1

1st

Question 2

What generation? Progestin norethindrone

Answer 2

1st

Question 3

What generation? Progestin norethindrone acetate

Answer 3

1st

Question 4

What generation? Progestin ethynodiol diacetate

Answer 4

1st

Question 5

What generation?

• Well tolerated
• Found in many generic formulations and some low-dose brand-name COCs
• Unscheduled bleeding/spotting at lower doses

Answer 5

1st

Question 6

What generation? Progestin norgestrel

Answer 6

2nd

Question 7

What generation? Progestin levonorgestrel

Answer 7

2nd

Question 8

What generation?

• Potent with long half-life
• Increase in androgen-related side effects (adverse effects on lipids, oily skin, acne, facial hair)

Answer 8

2nd

Question 9

What generation? Progestin desogestrel

Answer 9

3rd

Question 10

What generation? Progestin norgestimate)

Answer 10

3rd

Question 11

What generation?

• Reduced androgenic SEs
• Fuller impact of estrogen which may increase risk of thromboembolism

Answer 11

3rd

Question 12

What generation?

• Antimineralcorticoid and antiandrogenic properties
• Tx of PMDD and acne
• No increased risk of thromboembolism

Answer 12

4th

Question 13

What generation? Progestin drospirenone

Answer 13

4th

Question 14

What generation?

More profound, diverse, and discreet endometrial effect compared to others (progestin).

Answer 14

Next Generation

Question 15

What generation of estrogen?

• Availability: 20, 25, 30, 35, 50 mcg and one preparation containing 10mcg

Answer 15

Next Generation

Question 16

What generation? Progestin dienogestrel

Answer 16

Next Generation

Question 17

What generation? Estrogen ethinyl estradiol (EE)

Answer 17

Next Generation

Question 18

Name the 1st generation progestins (4).

Answer 18

• Norethynodrel
• Norethindrone
• Norethindrone acetate
• Ethynodiol diacetate

Question 19

Name the 2nd generation progestins (2).

Answer 19

• Norgestrel
• Levonorgestrel

Question 20

Name the 3rd generation progestins (2).

Answer 20

• Desogestrel
• Norgestimate

Question 21

Name the 4th generation progestin (1).

Answer 21

Drospirenone

Question 22

Name the next generation hormones (2).

Answer 22

• Progestin: dienogestrel
• Estrogen: ethinyl estradiol

Question 23

Which generation would you avoid for someone with acne or facial hair growth?

Answer 23

2nd generation

Question 24

Which generation has more spotting and unscheduled bleeding at lower doses?

Answer 24

1st generation

Question 25

Which generation has a lesser androgenic effects, but more estrogenic effects leading to a possible increased risk for venous thromboembolism?

Answer 25

3rd generation

Question 26

Which generation is best for treatment of acne and PMDD?

Answer 26

4th generation

Question 27

Which generation has more profound, discreet, and diverse endometrial effects compared to other progestins?

Answer 27

Next generation