1 - Hematopoiesis Flashcards

(39 cards)

0
Q

Megakaryopoiesis

A

Platelet development

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1
Q

T-cell markers

A

CD3, CD2, CD5, CD4/CD8

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2
Q

Programmed cell dreary

A

Apoptosis

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3
Q

Formation and development of formed elements of blood

A

Hematopoietic

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4
Q

Factory of blood cells

A

Bone marrow

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5
Q

Formation and development of RBC

A

Erythropoiesis

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6
Q

Life span of RBC

A

~120 days

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7
Q

Reduced oxygen carrying capacity

A

Anemia

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8
Q

Formation of leukocyte

A

Leukopoiesis

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9
Q

Formation of basophils, eosinophils and neutrophils

A

Granulopoiesis

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10
Q

Earliest form of granular leukocytes

A

Myeloblast

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11
Q

Hematopoietic response for HYPOXIA

A

RBC production

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12
Q

Hematopoietic response for INFECTION

A

Granulocyte

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13
Q

Hematopoietic response for ANTIGEN

A

Lymphocyte

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14
Q

Hematopoietic response for hemorrhage

A

Platelets

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15
Q

Phases of erythropoiesis

A
  1. Ribosome development
  2. Hemoglobin accumulation
  3. Ejection of nucleus and formation of reticulocytes
16
Q

B-cell and T-cell maturation

A

Lymphopoiesis

17
Q

Regulated by thrombopoietin

A

Megakaryopoiesis

18
Q

Biconcave anucleated discs

19
Q

Immature red blood cells

A

Reticulocytes

20
Q

Minute biconvex anucleate cells

21
Q

Arises from fragmentation of cytoplasm of the megakaryocytes from the bone marrow

22
Q

Spherical in bloodstream but pleiomorphic ameboid cells in tissues

23
Q

Granular leukocytes

A

Eosinophils, neutrophils, basophils

24
Nongranular leukocytes
Lymphocytes and monocytes
25
Polymorphonuclear leukocytes
Neutrophils
26
First line of defense against infection by bacteria
Neutrophils
27
Supplement the function of mast cells in immediate hypersensitivity reactions by migrating to tissue
Basophil function
28
Humoral immunity
B cells
29
Cellular immunity
T cells
30
Types of T cells:
1. Cytotoxic T cells or Killer cells 2. Helper T cells 3. Suppressor T cells
31
Further stimulates B lymphocytes to produce antibodies
Helper T cells
32
Largest WBC in normal blood
Monocytes
33
Process antigens and present them to lymphocytes
Monocyte function
34
Defense against viruses in blood, and clean-up (phagocytosis) in BM and tissue
Monocyte function
35
Maintains colloid osmotic pressure of blood
Albumin
36
Most abundant plasma protein
Colloid
37
Fluid matrix in which blood cells are suspended
Plasma
38
Composition of blood plasma:
1. Water - 90% 2. Proteins - 8% 3. Other solutes - 2%