1 - Hematopoiesis Flashcards
(39 cards)
Megakaryopoiesis
Platelet development
T-cell markers
CD3, CD2, CD5, CD4/CD8
Programmed cell dreary
Apoptosis
Formation and development of formed elements of blood
Hematopoietic
Factory of blood cells
Bone marrow
Formation and development of RBC
Erythropoiesis
Life span of RBC
~120 days
Reduced oxygen carrying capacity
Anemia
Formation of leukocyte
Leukopoiesis
Formation of basophils, eosinophils and neutrophils
Granulopoiesis
Earliest form of granular leukocytes
Myeloblast
Hematopoietic response for HYPOXIA
RBC production
Hematopoietic response for INFECTION
Granulocyte
Hematopoietic response for ANTIGEN
Lymphocyte
Hematopoietic response for hemorrhage
Platelets
Phases of erythropoiesis
- Ribosome development
- Hemoglobin accumulation
- Ejection of nucleus and formation of reticulocytes
B-cell and T-cell maturation
Lymphopoiesis
Regulated by thrombopoietin
Megakaryopoiesis
Biconcave anucleated discs
Erythrocytes
Immature red blood cells
Reticulocytes
Minute biconvex anucleate cells
Platelets
Arises from fragmentation of cytoplasm of the megakaryocytes from the bone marrow
Platelets
Spherical in bloodstream but pleiomorphic ameboid cells in tissues
Leukocytes
Granular leukocytes
Eosinophils, neutrophils, basophils