1. periodontitis and systemic disease Flashcards
(38 cards)
What happens to the junctional epithelium when gingivae is inflamed?
The junctional epithelium becomes leaky, allowing bacteria and inflammatory mediators to enter the bloodstream.
What can bacteria in the bloodstream cause?
Damage to various systems in the body.
How can inflammatory mediators in the bloodstream affect chronic inflammation?
They can worsen chronic inflammation.
List some systemic diseases strongly associated with periodontal disease.
- Diabetes
- Cardiovascular disease
- Adverse pregnancy outcomes
- Respiratory disease
- Kidney disease
- Osteoporosis
- Alzheimer’s disease
- Inflammatory bowel disease
What are the two ways systemic conditions affect periodontal tissue?
- Affecting the progression of plaque-induced periodontitis
- Affecting the periodontium independently of dental-induced inflammation
systemic disorders are classified into 3 groups what are they?
- Group 1: Major impact on loss of periodontal tissues by influencing periodontal inflammation
- Group 2: Influence the pathogenesis of periodontal diseases
- Group 3: Result in loss of periodontal tissues independent of periodontitis
based on the 2018 periodontal classification what section are group 1 (Major impact on loss of periodontal tissues by influencing periodontal inflammation) part of?
periodontitis as a manifestation of systemic disease
What characterizes Group 1 systemic disorders?
They worsen periodontitis by downgrading the host response.
what types of systemic disorders are part of the classification group 1: Systemic disorders that have a major impact on the loss of periodontal tissues by influencing periodontal inflammation
Diseases associated with immunological disorders
Diseases affecting the oral mucosa and gingival tissue
Diseases affecting the connective tissues
Metabolic and endocrine disorders
Acquired immunodeficiency diseases
what classification is down syndrome in?
Group 1: Systemic disorders that have a major impact on the loss of periodontal tissues by influencing periodontal inflammation
periodontitis as a manifestation of systemic disease
how does Down syndrome link to periodontitis?
Immune defects and tendency to have poor OH so predisposed to perio disease at an earlier age
what classification is Papillon-Lefevre syndrome
Group 1: Systemic disorders that have a major impact on the loss of periodontal tissues by influencing periodontal inflammation
periodontitis as a manifestation of systemic disease
how does papillon-lefevre syndrome link to periodontitis?
Severe periodontitis and teeth fall out early
Very resistant to perio treatment
what classification is Chediak-higashi syndrome in
Group 1: Systemic disorders that have a major impact on the loss of periodontal tissues by influencing periodontal inflammation
periodontitis as a manifestation of systemic disease
how does Chediak-higashi syndrome link to periodontitis?
evere periodontitis and teeth fall out early
} Responds poorly to perio treatment
what classification is Cyclic neutropoenia in?
Group 1: Systemic disorders that have a major impact on the loss of periodontal tissues by influencing periodontal inflammation
periodontitis as a manifestation of systemic disease
how does cyclic neutropenia link to periodontitis?
Neutrophil levels go up and down in a cycle
Oral ulceration and rapid periodontal destruction when low neutrophil numbers
what classification is Epidermolysis bullosa in?
Group 1: Systemic disorders that have a major impact on the loss of periodontal tissues by influencing periodontal inflammation
periodontitis as a manifestation of systemic disease
how does epidermolysis bullosa link to periodontitis?
affecting the oral mucosa and gingival tissue so more susceptible to periodontitis
what classification is Ehlers-Danlos syndrome in?
Group 1: Systemic disorders that have a major impact on the loss of periodontal tissues by influencing periodontal inflammation
periodontitis as a manifestation of systemic disease
what types of Ehlers-danlos syndrome are linked to periodontitis?
Type IV - bleeding tendency
Type VIII - associated with aggressive grade C periodontitis
what classification is Hypophosphatasia in?
Group 1: Systemic disorders that have a major impact on the loss of periodontal tissues by influencing periodontal inflammation
periodontitis as a manifestation of systemic disease
how does Hypophosphatasia link to periodontitis
Deficiency in enzyme alkaline phosphatase
Abnormal mineralisation of bones and teeth
Lose primary teeth early
Permanent teeth aren’t affected
what classification is HIV in?
Group 1: Systemic disorders that have a major impact on the loss of periodontal tissues by influencing periodontal inflammation
necrotising periodontal disease
