1- therapeutics

Question 1

more shine on rash means which layer involved?

Answer 1

dermis

Question 2

what does vulgaris mean?

Answer 2

common

Question 3

what are some prescribing tips for emollients?

Answer 3

they’re to rehydrate dry or scaly conditions

• best to apply after bath in direction of hair growth
• remember that could be fire risk if paraffin based

Question 4

what is wet wrap therapy?

Answer 4

used for very dry skin where wrap up with emollient

Question 5

what is a mild to very potent topical corticosteroid? (there are 4)

Answer 5

• mild = hydrocortisone 1%
• moderate = modrasone clobetasone butyrate 0.05%
• potent = mometasone betamethasone valerate 0.1%
• very potent = clobetasol propionate 0.05%

Question 6

what is fingertip rule?

Answer 6

1 fingertip unit of topical corticosteroid = 1/2g which covers 2 hand areas

Question 7

what are side effects of topical steroids?

Answer 7

• can make rebound flare! (especially in psoriasis)
• thinning of skin, purpura, stretch marks
• steroid rosacea (red cheeks), perioral dermatitis, fixed telangiectasia

Question 8

when are antiseptics used? like in general?

Answer 8

recurrent infections, skin cleansing, wound irrigation

Question 9

what are antivirals used for?

Answer 9

• herpes simplex (cold sore)
• eczema herpeticum
• herpes zoster (shingles)

Question 10

what are antifungals used for?

Answer 10

• candida (thrush) e.g. nystatin clotrimazole
• dermatophytes (ringworm) e.g. clotrimazole, terbinafine cream
• pityriasis versicolor e.g. ketoconazole as cream or shampoo

Question 11

what is psoriasis treatment?

Answer 11

emollient and choice of
- coal tar
- vit D analogue (dovonex)
- keratolytic
- topical steroid
- dithranol

Question 12

what are side effects of topical therapies?

Answer 12

• burning or irritation
• contact allergic dermatitis
• local toxicity
• systemic toxicity

systemic = hypercalcaemia & hypercalciuria, suppress pituitary

Question 13

when would you use topical corticosteroids? what conditions?

Answer 13

• eczema
• psoriasis
• other non infective inflammatory dermatoses e.g. lichen planus

Question 14

what are some examples of antipruritics?

Answer 14

• menthol
• capsaicin
• camphor/phenol
• crotamiton (eurax cream)

Question 15

what is 5-fluorouracil? when used?

Answer 15

cream that treats precancerous lesions - for solar damage, bowen’s disease & superficial basal cell carcinoma

Question 16

what is imiquimod? when used?

Answer 16

immune suppressant cream, for solar damage & superficial basal cell carcinoma