10. Structure of liver (broad anatomy & histology) Flashcards

1
Q

How many lobes does the liver have? Name them

A

4 lobes
Left and right lobes
caudate lobe
quadrate lobe

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2
Q

What are the two main cell types of the liver?

A
Hepatocytes
Kuppfer cells (macrophages of the liver)
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3
Q

How many segments does the liver have?

A

8

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4
Q

What is the surface landmark of the liver for percussion?

A

Right 5th intercostal space

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5
Q

What separates the 2nd and 3rd segments from the 4th segments (a&b)?

A

Falciform ligament

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6
Q

What is the blood supply and drainage of the liver?

A

Supplied by the hepatic artery (oxygenated blood) and portal vein (deoxygenated blood)
Drained by the hepatic vein

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7
Q

What does the porta hepatis consist of?

A

Portal vein
Hepatic artery
Hepatic duct (left and right)

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8
Q

What structure lies between the bare area of the liver and the caudate lobe?

A

Inferior vena cava

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9
Q

List the 3 ligaments of the liver

A
Falciform ligament
coronary ligament (approx outline bare area)
Round ligament (ligamentum teres)
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10
Q

What sits between the right lobe and the quadrate lobe?

A

Gallbladder

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11
Q

What is the significance of the ligamentum teres (round ligament)?

A

It is the obliterated umbilical vein, forming the free edge of the falciform ligament

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12
Q

Which lobe is the largest?

A

Right lobe

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13
Q

Which lobe sits between the gallbladder and the round ligament of the liver?

A

Quadrate lobe

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14
Q

What lies between the IVC, ligamentum venous and the porta hepatis?

A

The caudate lobe

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15
Q

What separates the plates of hepatocytes?

A

Sinusoids

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16
Q

What is the definition of a hepatic lobule?

A

Hexagonal units of cells around a central vein, with portal triads at the margins

17
Q

Describe the 3 features of the sinusoidal surfaces which aid the exchange of material in hepatocytes

A
  1. Fenestrated
  2. Deliberately more leaky
  3. Incomplete basement membrane
18
Q

List the 3 types of surfaces present on hepatocytes

A

Sinusoidal
Intercellular
Canalicular