medication and U+E's

Question 1

bendroflumethiazie (thiazide diuretic)

Answer 1

site of action: distal tubule, inhibits the Na+/Cl- sympoter.

MOA: Na+ and K+ loss in urine, Ca2+ resorption from urine

SE: hyponatraemia, hypokalaemia, hypercalcaemia

Question 2

loop diuretics

Answer 2

works on the thick ascending loops of henle and inhibits the Na+/K+/2Cl supporter.

Na+, K+ and Ca2+ are lost in the urine
hyponatraemia, hypokalaemia, hypocalcaemia

Question 3

carbonic anhydrase inhibtiors

Answer 3

site of action: PCT, inhibits HCO3- resorption

produced alkaline urine the tis rich in HCO3

Question 4

aldosterone antagonist (spironolactone)

Answer 4

site of action: distal tubular and collecting tubulues

inhibitos aldosterone mediated Na+ and K+ excretion

poduced hyperkalaemia