Omalizumab Flashcards

1
Q

MECANISMO DE ACCIÓN

A

Anticuerpo monoclonal IgG1, que inhibe la unión de la IgE a sus receptores FcεRI y FcεRII (CD23) en los mastocitos y basófilos

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2
Q

INDICACIONES CLÍNICAS

A

Asma

Urticaria crónica idiopática

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3
Q

Pk

A

Subcutánea
M: hepático
E: biliar

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4
Q

RAM

A
Reacción local en el sitio de inyección
Anafilaxia
Fiebre
Cefalea
Artralgia
Dolor abdominal
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5
Q

INTERACCIONES

A

No presenta interacciones

de importancia clínica

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6
Q

PRECAUCIONES

A
Anafilaxia
Crisis asmática
Espasmo bronquial
Helmintiasis
Insuficiencia hepática y renal
Reacción autoinmune
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7
Q

CONTRAINDICACIONES

A

Hipersensibilidad

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8
Q

🤰

A

?

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