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Cvs > Cardiac Action Potential > Flashcards

Cardiac Action Potential Flashcards

1
Q

Ventricular action potential has … phases

A 
4phases
0
1
2
3
4
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2
Q

Phase 0 is …

Caused due to….

A

Early depolarisation

Na+ influx

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3
Q

Phase 1

A

Early repolarization

K+ efflux

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4
Q

Phase 2

A

Plateau phase
K+ efflux= Ca+ influx(L-type)
Ltype Ca+ closes at the end of phase2

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5
Q

Phase3

A

Late repolarization

K+ efflux

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6
Q

Phase4

A

Resting membrane potential

Na+ —k+ pump

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7
Q

Dromotropy

A

Property of conduction

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8
Q

Chronotropy

A

Heart rate

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9
Q

Inotropy

A

Myocardial contractility

Ventricular action potential

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10
Q

Bathmotropy

A

Cardiac excitability

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11
Q

Lucitropy

A

Cardiac relaxation

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12
Q

Sa node responsible for ….

A

Automacity

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13
Q

Automacity?

A

Ability to generate impulse even in the absence of external stimulus

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14
Q

Sa nodal potential( max)

A

100/min

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15
Q

….. reduces Sa nodal potential from 100 to 72/min

A

Parasympathetic system

Via resting vagal tone

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16
Q

Name the automatic tissues

A

Sa node
Av node
His- purkinje system
Atrial cells near ostium of coronary sinus

17
Q

Sa node action potential also known as

A

Pacemaker potential
Pre potential
Restless membrane potential spontaneous diastolic depolarization
Slow response action potential

18
Q

Moat imp parameter that determine slope of action potential

A

Ans- autonomic nervous system

19
Q

Vaughan william classifn of antiarrhythmic drjg has … classes

A

Class 1,2,3,4

20
Q

Class 1 are … blockers and divided into…..

A

Na+ channel blockers

Divided into Ia, Ib, Ic

21
Q

Class2 are…

Aact on….

A

Beta blockers

Phase 4

22
Q

Class3 are …. blockers

Act by….

A

k+ channel blockers

Prolongs QT

23
Q

Eg.s for class3

A 
BIDAS
Bretylium 
Ibutilide
Dofetilide
Amiodarone
Sotalol
24
Q

Wat is sotalol

A

Antiarryhthmic agent action via K+ channel blocker predominantly

25
Q

Myocardial oxygen consumption

A

8ml/100g/min

Cvs (6 decks)

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