Benign Prostatic Hyperplasia

Question 1

What is Benign Prostatic Hyperplasia characterised by

Answer 1

Fibromuscular and Glandular Hyperplasia

Question 2

Benign Prostatic Hyperplasia predominantly affects

Answer 2

Transition Zone

Question 3

50% of men with Benign Prostate Hyperplasia have

Answer 3

Mod to Severe LUTS

Question 4

Benign Prostatic Hyperplasia may result in

Answer 4

Bladder outflow Obstruction

Question 5

International Prostate Score Mild

Answer 5

0-7

Question 6

International Prostate Score Moderate

Answer 6

8-19

Question 7

International Prostate Score Severe

Answer 7

> 20

Question 8

Assessing LUTS: What is associated with Voiding (Obstructive)

Answer 8

Hesistancy
Poor Stream
Terminal Dribble
Incomplete Empty

Question 9

Assessing LUTS: What is associated with Storage (Irritative)

Answer 9

Frequency
Nocturia
Urgency
Incotinence

Question 10

Investigations for Prostate Disease

Answer 10

MSSU
Flow Rate Study
Post Void Bladder Residual USS
PSA Bloods

Question 11

If there is Haematuria in urine what test

Answer 11

Flexible Cytoscopy

Question 12

If PSA raised or abnormal DRE what test

Answer 12

TRUS guided Prostate Biopsy

Question 13

Medical Treatment of Uncomplicated BPO

Answer 13

Alpha Blockers

5 Alpha Reductase Inhibitors (Finasteride or Dutasteride)

Question 14

Name 2 - 5 Alpha Reductase Inhibitors

Answer 14

Finasteride

Dutasteride

Question 15

Surgical Intervention of Uncomplicated BPO if Prostate <100

Answer 15

TURP if Prostate <100

Question 16

Surgical Intervention of Uncomplicated BPO if Prostate >100

Answer 16

Open Retropubic or Transversical Prostatectomy

Question 17

Main Treatment for LUTS due to BPO

Answer 17

Alpha Blockers

Question 18

Smooth muscle of bladder neck and prostate innervated by

Answer 18

sympathetic alpha-adrenergic nerves

Question 19

sympathetic alpha-adrenergic nerves are mostly what type

Answer 19

alpha 1a subtype

Question 20

Alpha blockers cause what to bladder

Answer 20

smooth muscle relaxation and antagonise the ‘dynamic’ element to prostatic obstruction

Question 21

5a reductase inhibitors converts what to dihydrotestosterone

Answer 21

testosterone

Question 22

What drug reduces prostate size and risk of progression of BPE but only if >25cc prostate

Answer 22

5a reductase inhibitors

Question 23

Gold Standard Surgical for BPE

Answer 23

TURP

Question 24

Complications of BOO

Answer 24

Progression of LUTS
Acute Retention
Chronic retention
Urinary Incontinence
Bladder Stone

Question 25

Treatment of Complicated BOO

Answer 25

Medical
Cystiolithopaxy and TURP when BPO and Stones
Long Term Catheter