chapter 1 Flashcards
Describe the branching of the airway
CONDUCTING AIRWAYS: (16 divisions)
trachea - bronchi - lobar - segmental - terminal
RESPIRATORY ZONE: (7 divisions)
respiratory bronchioles - alveolar ducts
Portion of lung distal to terminal bronchiole is called the acinus
How many generations of airways are there?
What is conducting zone?
What is transitional and respiratory zones?
23 generations of airways
conducting: 1-16
respiratory zones: 17-23
What is the volume of the anatomic dead space in adults?
150 ml
what is the volume of the alveolar region?
about 2.5-3 litres
How is gas moved in the airways?
convective flow in conducting airways, then diffusion in respiratory zone
Describe the cross sectional area of the airways
increases down the airway generations (extremely rapid increase in the respiratory zone)
What is the thickness of the blood-gas interface?
What is the surface area of the lung?
What is the diameter of a capillary?
0.2-0.3 um over much of the area
surface area is 50-100 m2
7-10 um
Where do inhaled articles settle out? how are they removed?
Settle out in the conducting airways and removed by mucociliary elevator.
Alveoli have no cilia - particles are cleared by macrophages.
mucus secreted by mucous glands and goblet cells
how do the vessels branch in the lung?
Venous: initially runs with arteries and bronch. Toward periphery of lung, move away to pass between the lobules.
Arterial: pulm arteries and bronchi travel together
What does the bronchial circulation supply?
Supplies conducting airways down to the terminal bronchioles