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Pharmacology > Misc > Flashcards

Misc Flashcards

0
Q

Meropenem

Carbapenem

A

1g IVPB q 8hrs

ID consult - gram negatives

Resistance from KPC and NDM

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1
Q

Vancomycin

A

15-20mg/kg IVPB q 8-12hrs

Staph
Check serum level before 5th dose, should be between 15-40mcg/dL

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2
Q

Ciprofloxacin

Fluoroquinalone

A

500mg oral q 12hrs 3 days

UTI gram negative

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3
Q

Levofloxacin

Fluoroquinalone

A

500mg oral q 24hrs 7-14 days

CA-PNA gram positive

Can switch from IV p one dose

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4
Q

Moxifloxacin

Fluoroquinalone

A

400mg oral

CA-PNA

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5
Q

Fluoroquinalone side effects

A

QTc elongation

Tendonitis

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6
Q

Erythromycin

Macrolide

A

500mg oral q 6hrs

URI

Biliary excretion

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7
Q

Azithromycin

Macrolide

A

500mg oral q 24hrs

CA-PNA

Biliary excretion

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8
Q

Macrolide side effects

A

Eryth: QT prolongation, motalin
Azith: cardiac risk

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9
Q

Gentamicin

Aminoglycoside

A

1.3-1.7mg/kg IVPB q 8hrs

Meningitis

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10
Q

Tobramycin

Aminoglycoside

A

1.3-1.7mg/kg IVPB q 8hrs

Pseudomonas

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11
Q

Neomycin

Aminoglycoside

A

Topical (or oral for GI sterilization)

Strep/staph

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12
Q

Aminoglycoside side effects

Check trough level if more than 3 days, if increasing, renal toxicity!

A 
Ototoxicity:
  Gent-balance
  Neo-deafness
  Tobra-both
Nephrotoxicity
Neuromuscular blockade
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13
Q

Doxycycline

Tetracycline

A

100mg IVPB q 12hrs

Chlamydia

Liver adjust

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14
Q

Tigecycline

Tetracycline

A

100mg IVPB x 1 dose, then
50mg IVPB q 12hrs

ID consult, liver adjust

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15
Q

Tetracycline side effects

A

Photosensitivity
Bony structures
CNS

Resistance from efflux pump

16
Q

Clindamycin

Lincosamide

A

300-450mg oral q 8hrs 5-10 days

Bacteroides

17
Q

Trimethoprim/Sulfamethoxazole

Sulfonamide

A

160/800mg oral q 12hrs 3-5 days

UTI

18
Q

Sulfonamide side effect

A

Dermatologic
Crystalluria
Acute hemolytic anemia
Necrosis of liver

19
Q

Linezolid

Staph Hunter

A

600mg IV or oral q 12hrs 10-14 day

MRSA

20
Q

Daptomycin

Staph Hunter

A

4mg/kg IVPB q 24hrs 7-14 days

MRSA

21
Q

Staph Hunter side effects

A

Linezolid: thrombocytopenia, SSRI interactions
Daptomycin: eosinophilic PNA, myopathy (check CK-MM)

Pharmacology (13 decks)

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