2.10 Chronic Lung Disease of Prematurity

Question 1

What is another name for chronic lung disease of prematurity?

Answer 1

bronchopulmonary dysplasia

Question 2

What gestation prematurity is particularly increased risk for bronchopulmonary dysplasia / CLDP?

Answer 2

typically born before 28 weeks

may have respiratory distress syndrome, O2, ventilation

Question 3

How is bronchopulmonary dysplasia / CLDP diagnosed?

Answer 3

Diagnosed at 36 weeks gestational age when child still needs O2 and have Xray changes

Question 4

Features or appearance of bronchopulmonary dysplasia / CLDP?

Answer 4

• low sats
• work of breathing
• poor feeds, poor weight gain
• increased infections
• CRACKLES and WHEEZE

Question 5

How can you prevent bronchopulmonary dysplasia / CLDP before birth?

Answer 5

give betamethasone to mum when prem labour <36 weeks

Question 6

Once neonate is born, 3 things to reduce risk of bronchopulmonary dysplasia / CLDP?

Answer 6

• use CPAP rather than intubation where possible
• caffeine to stimulate resp effort
• not giving too much O2

Question 7

What do babies with bronchopulmonary dysplasia / CLDP get weaned off once they are discharged home?

Answer 7

Wean off oxygen, low dose eg 0.01 L/min

Question 8

What infection is a risk for babies with bronchopulmonary dysplasia / CLDP?

Answer 8

RSV infection causing bronchiolitis

Question 9

Would should some bronchopulmonary dysplasia / CLDP babies get injected and why?

Answer 9

monthly palivizumab injection,
to protect against RSV (about £500 per shot)

(not all cases)