10.2 - Dermatology Diseases Flashcards
(39 cards)
What are the words to describe small and large lumps
- papule are small (less than 5mm)
- nodules are larger (more than 5mm)
What are the words to describe small and larger water blisters
- vesicle is small water blister
- bulla is larger water blister
What is the word to describe pus-filled vesicle
Pustule
What is the word for redness
Erythema
What is the word to describe a non-palpable area of discolouration (large and small)
- macule are small
- patch are larger (2cm +) macules
- Non-palpable means its in line with skin
What is a palpable, flat topped area (greater than 2cm)
Plaque
Palpable – raised from skin
What is the medical word for a scratch
Excoriation (mention the length of them)
Word for stretch marks
Striae
Word for itch
Pruritis
What does ‘atrophy’ mean
Thinning
What is a telangiectasia
- A thread vein
- Can be normal or pathological
What is ichthyosis
Scaling of skin
What are the words for loss of epidermis, and loss of epidermis + dermis
- erosion if loss of epidermis (eg scrape of knee). Superficial
- ulcer if loss of epidermis and dermis (eg due to venous insufficiency.
What is lichenification
Thickening of the skin with exaggerated skin markings
What are the words for too much hair and too little/thinning hair
What are the words for too much hair and too little/thinning hair
- hirsutism is too much hair
- alopecia is too little hair
The process of inflammation results from three major events…
- vasodilation - cells coming into inflamed areas
- increased microvascular permeability resulting in production of protein rich exudate, so body can fight off infection
- influx of leukocytes
Main signs + symptoms of inflammation
- Rubor (redness/erythema)
- Tumor (growing/swelling)
- Calor (heat)
- Dolor (pain)
- Functio laesa (loss of function eg joint inflammation)
Features and possible causes of psoriasis
- Presence of acanthosis (thicker layer that is raised from the skin)
- Reduced epidermal transit time of keratinocyte from basal → superficial layer (stratum corneum) ☞ results in thicker layer of epidermis
- Erythema – due to increased vascularity of the upper dermis → more blood
cause: may be inherited, since family members suffer from psoriasis simultaneously. There may be triggers that can cause a flare up in individuals with an underlying presdisposition to psoriasis. Triggers on different card.
What are some common psoriasis triggers
these can trigger a flare-up in individuals who are already predisposed to psoriasis
- An injury to skin
- Excessive alcohol
- Smoking
- Stress
- Hormonal changes (more important in women, eg puberty + menopause)
- Certain medications (eg lithium, antimalarial meds, anti-inflammatory, ACE inhibitors)
- Other immune disorders
How to differentiate between eczema + psoriasis
usually found on extensor surfaces, whereas eczema usually on flexor surfaces
- Psoriasis found on knees, elbows, forehead
- Eczema usually found behind knees + elbows
What are some other common signs of psoriasis (not plaques on skin)
- Pitting of nails
- Increased growth of nail, causing separation of the nail from the nail bed (nails also have keratin)
- Joint problem
Treatment of psoriasis
topical
- Emollients
- Salicyclic acid
- Topical steroids
- Vitamin D analogues
systemic
- Psoralen + PUVA (UV light treatment)
- Cytotoxic drugs
- Retinoids (caution women of childbearing age)
- Monoclonal antibodies
What is atopy
Asthma, hayfever and eczema all together
What is eczema + it’s features
- Dermatitis: inflammation of the skin
- A chronic dermatological disease
- Can be found all over the body, but most commonly on flexor surfaces eg back of wrists, behind knees and behind elbows
- Very itchy and red