Oral mucosa Flashcards

1
Q

functions of oral mucosa

A

protection
sensation
thermal regulation
secretions

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2
Q

2 parts of oral cavity

A

vestibule bounded by lips and cheeks

and oral cavity which is separated from the vestibule by alveolar bone and gingiva

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3
Q

types of oral mucosa

A

lining
masticatory
specialized

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4
Q

% of each type of mucosa

A

60% IS Lining
25% Masticatory
15% specialized

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5
Q

the coloration depends on

A

the number of vessels and their dilation in underlying connective tissue
amount of melanin pigment present
degree of keratinization
thickness of epithelium

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6
Q

sebaceous glands are found in?

A

upper lip, buccal mucosa and in about 3 quarters of adults in masticatory mucosa and dorsum of the tongue

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7
Q

sebaceous appear as yellow spot known as

A

Fordyce’s spot

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8
Q

what present on the dorsum of the tongue and hard palate

A

papillae and transverse ridges (Rugae) respectively

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9
Q

two main tissues of oral mucosa

A

stratified squamous epithelium

and lamina propria (underlying connective tissues)

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10
Q

what separates the oral mucosa from the underlying muscle or bone in lips cheeks hard palate

A

a lose fatty or glandular connective tissue containing major blood vessels and nerves

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11
Q

mucoperiosteum

A

the oral mucosa such as gingiva and hard palate is directly attached to periosteum known as

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12
Q

waldeyers ring

A

largest accumulation of lymphoid tissues are found in posterior part of oral cavity
(lingual, palatine and pharyngeal)

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13
Q

2 Functional populations of epithelium cells of oral mucosa

A
progenitor population (that divide and provide new cells)
maturating population ( that continually mature and differentiate)
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14
Q

cell turnover

A

the time taken for a cell to divide and pass though the entire epithelium is known as turnover rate

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15
Q

skin turnover time

A

52 to 75 days

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16
Q

gut turn over time

A

4 to 14 days

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17
Q

gingiva turn over time

A

41 to 57 days

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18
Q

cheek turn over time

A

25

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19
Q

turn over rate is faster in

A

non keratinized epithelium such as the buccal mucosa rather than the gingiva

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20
Q

keratinized epithelium what type of mucosa

A

masticatory and specialisez

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21
Q

where is keratinized epithelium present

A

hard palate, gingiva, dorsum of the tongue

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22
Q

each layer in keratinized epithelium and the shape of their cells

A
  1. stratum basale ( cuboidal or low columnar)
  2. stratum spinosum or prickle cell layer (elliptical or spherical cells)
  3. stratum granulosam ( flattened cells)
  4. startum corneum ( flat squamous cells) no nuclei
23
Q

ortho keratnized

A

startum corneum with no nuclei

24
Q

para keratinized

A

a variation of keratinized layer in which startum corneum have flattened nuclei called pyknotic nuclei

25
Q

why startum spinosum have prickled cells reason?

A

in histological preparatuon their cells shrink away remaining in contact with other cells through desmosomes.

26
Q

startum granulosum stains?

A

intensely with acid dyes ( hematoxylin) basophilic

27
Q

stratum granulosum contains?

A

granules called keratohyalin granules

28
Q

startum corneum stains

A

dark pink with eosin

29
Q

non keratinized epithelium is present in what mucosa

A

lining mucosa

30
Q

lining mucosa is present in

A

lips, buccal mucosa, alveolar mucosa, soft palate underside of the tongue, soft palate and floor of the mouth

31
Q

layers or non keratinized

A

first 2 layers are different

stratum intermedium in place of stratum granulosum and stratum superficiale

32
Q

clinical significance of turnover

A

the drugs target the cell in CANCER patients which have a high rate of turnover like the cells of hair and nails

33
Q

keratinocyte with small molecular weight

A

40kDa found in glandular and simple epithelium

34
Q

keratinocyte with intermediate molecular weight

A

found stratified epithelia

35
Q

keratinocyte with high molecular weight

A

65Kda is found in stratified keratinized epithelium

36
Q

non keratinocytes cell in oral epithelium

A

melanocytes
langerhans cells
lymphocyte
Merkels cell

37
Q

location of each type of non keratinized cell

A

melanocyte is present in basal layer para basal
langerhans are present in supra basal
merkel cell is present in basal layer
and lymphocytes are variable

38
Q

what are the only non dentritic non keratinocytes ?

A

merkels cells

39
Q

what cells have desmosomes for attahcment of adjacent cells

A

merkels cells

40
Q

where melanin pigment is most seen

A

gingiva, hard palate, tongue buccal mucosa

41
Q

causes of high activity of melanocytes

A

smoking
genetically
drugs
high cortisone level

42
Q

melanin is synthesized within melanocytes as small structures called as

A

melanosomes

43
Q

person with heavy melanin pigment the cell containing melanin may be seen in

A

connective tissue which are usually macrophages that take up the melanosomes and are called melanophages

44
Q

one special characterstic about langerhan cells

A

rod shaped granule or tennis racket shaped granules which are called BIRBECK GRANULE

45
Q

langerhans cells are made in

A

bone marrow

46
Q

mucogingival junction

A

junction between attached gingiva and alveolar mucosa

47
Q

epithelium of attached and alveolar mucosa

A

attached gingiva has keratinized masticatory mucosa

alveolar mucosa has non keratinized lining epithelium

48
Q

space between tooth and gingiva and clinical significance

A

gingival sulcus (contains tartar and bacteria)

49
Q

what is present between free gingiva and attached gingiva

A

free gingival grove

50
Q

junctional epithelium

A

bewteen attached gingiva and tooth

51
Q

col

A

same as junctional epithelium and Replaced gradually by diving cell making more depression. interdental papillae have an outline of col
non keratinized

52
Q

when the lingual frenum is short its called

A

Ankyloglossia (frenectomy)

53
Q

linea alba

A

whitish ridge on the buccal mucosa at the occlusal plane of the teeth which is keratinized