MAOIs Flashcards

1
Q

Drugs

A
  • Selective
    • Selegiline
    • Rasagiline
  • Non-selective
    • Isocarboxazid
    • Phenelzine
    • Tranylcypromine
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2
Q

Mechanism of action

A
  • Selective
    • Inhibits monoamine oxidase B, increasing dopamine levels
  • Non-selective
    • Inhibits monoamine oxidase A and B, increasing serotonin, dopamine and norepinephrine
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3
Q

Contraindications

A
  • Cerebrovascular disease
  • Manic phase
  • Phaeochromocytoma
  • Severe caediovascular disease
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