Anti-epileptics Flashcards

1
Q

What are the (5) major anti-epileptics?

A

Phenytoin - Dilantin

Valproate - Depakote

Levetiracetam - Keppra

Lorazepam - Ativan

Diazepam - Valium

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2
Q

What are the indications for Phenytoin/Dilantin?

A
  • Focal seizures
  • Status epilepticus
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3
Q

What is the loading dose for phenytoin/dilantin?

A

IV 15mg/kg

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4
Q

What are the major side effects of phenytoin/dilantin?

A
  • QT prolongation
  • Hypotension
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5
Q

What is the indication for valproate/depakote?

A

Generalized seizures

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6
Q

What are the major SE of valproate/depakote?

A
  • Hepatotoxicity
  • Sedation
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7
Q

What are the indications for Lorazepam/ativan?

A
  • Anxiety
  • Status epilepticus
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8
Q

What are the indications for Levetiracetam/Keppra?

A

Seizures

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9
Q

What are the SE of Levitiracetam/keppra?

A
  • Somnolence
  • Dizziness
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10
Q

What is the loading dose for valproate/depakote?

A

20-40m/kg IV

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11
Q

What is the loading dose for levetiricetam/keppra?

A

20mg/kg

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12
Q

What is the IV and IM dose forr lorazepam/ativan?

A

IV = 2-4mg every 5-10 min

IM = 4mg

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13
Q

What are the major SE of lorazepam/ativan?

A
  • Respiratory depression
  • Hypotension
  • Poly ethylene glycol toxicity
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14
Q

What are the indications for diazepam/valium?

A
  • Anxiety
  • Seizures
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15
Q

What is the IV dosing for diazepam/valium?

A

0.15mg/kg every 5 minutes

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16
Q

What are the major SE of diazepam/valium?

A
  • Respiratory depression
  • Hypotension
17
Q

Which anti-epileptics are hepatotoxic?

A

Pehnytoin/dilantin

Valproate/depakote