Paralysis Flashcards

1
Q

botulism caused by what?

A

exotoxin, old cans, IVDA

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2
Q

paralysis in botulism?

A

descending paralysis

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3
Q

paralysis with CN palsy and dilated non reactive pupils?

A

botulism

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4
Q

diagnosis of botulism?

A

EMG with progressively increased muscle fiber contraction

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5
Q

weakness of GBS?

A

symmetric ascending weakness, loss of DTR

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6
Q

other symptoms of GBS?

A

autonomic and sensory issues

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7
Q

weakness with normal nerve conduction velocity? with decremental motor response to nerve stim

A

MG

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8
Q

MG pupillary effects?

A

none

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9
Q

treatment for MG?

A

pharesis removes the ach receptor ab, high dose steroids, pyridostigmine

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10
Q

causes of critical illness myopathy? sx?

A

steroids/flaccid quadriparesis

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11
Q

cause of critical illness polyneuropathy? sx?

A

sepsis/weakness, absent DTR, loss of distal sensation

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12
Q

tx of CIM and CIP?

A

tight glucose contral, prevent secondary issues

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13
Q

PE sign in spinal cord compression?

A

positive straight leg raise

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14
Q

central cord syndrome limbs?

A

upper limbs worse than lower

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15
Q

anterior cord syndrome location of injury

A

ASA occlusion

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16
Q

b/l spastic paralysis with loss of temp and pain distal to lesion?

A

anterior cord syndrome

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17
Q

loss of vibratory sense and proprioception, urinary retention?

A

posterior spinal cord

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18
Q

causes of posterior spinal cord syndrome?

A

vertebral srtery dissection, MS

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19
Q

ipsilateral weakness and loss of proprioception

contralateral loss of temp and pain

A

brown sequard syndrome- later half of the cord

20
Q

Miller fisher variant of GBS?

A

oculoparesis, ptosis, ataxia, areflexia

21
Q

tx of GBS?

A

IVIG or pharesis

22
Q

ticke borne paralysis sx?

A

tick needs to fed for 7 days first, also ascending paralysis

23
Q

MG sx? diagnosis?

A

ach receptor ab, proximal muscle weakness

24
Q

anti NMDA encephalitis association?

A

ovarian and testicular teratoma

25
Q

presentation of anti NMDA encephalitis?

A

young patient with paranoia or psychosis who deescalates to encephalopathy and seziures

26
Q

ascending paralysis complicated by areflexia and proprioception loss?

A

AIDP

27
Q

tx for AIDP?

A

plasmapharesis or IVIG

28
Q

tx for GBS?

A

IVIG or pharesis

29
Q

complications of IVIG?

A

anaphylaxis, aseptic meningitis, renal failure, fluid overload

30
Q

central cord syndrome cause? sx?

A

likely in setting of arthritis in older patients, loss of motor and sensory in arms and legs

31
Q

reversal of nondeploarizing NMB like cisatracurium?

A

neostigmine

32
Q

combat muscarinic effects of neostigmine?

A

glycopyrolate

33
Q

how does suggamadex work?

A

encapsulates NMBA in plasma and then creates a concentration gradiest to pull more out of muslce and eliminated via kidneys

34
Q

nutritional deficiency that can mimic GBS?

A

thiamine deficiecny- beriberi

35
Q

wernicke encephalopathy presentation?

A

vomiting, horizontal nystagmus, palsies of eye movement, fever, ataxia

36
Q

MIP and NIF threshold for MG?

A

> -20 NIF is bad, <40 on MIP bad, VC <15 cc/kg

37
Q

poor indicator for VC on MG assessment?

A

<20 cc/kg

38
Q

ice pack test for what?

A

improvement in ocular movement and proptosis, assessing for MG

39
Q

concern for excess pyridostigmine when treating MG?

A

cholinergic crisis

40
Q

treatment for MG

A

IVIG or pharesis for 5 days

41
Q

weakness with progressive decrement of action potentials with repetitive motion on electrophysiological studies?

A

MG

42
Q

weakness that will show electrophysiological with acute inflammatory demyelinating polyneuropathy

A

GBS

43
Q

cholingergic crisis in which of the weaknesses?

A

MG

44
Q

sx of cholingergic crisis in MG?

A

urinary retention, bradycardia, inc oral secretions, SLUDGE

45
Q

tx of cholingergic crisis in MG?

A

Supportive use atropine

46
Q

syringobulbia?

A

cysts in brainstem with gradual onset of motor, sensory, and autonomic sx

47
Q

when is it ok to use BIPAP in myasthenia crisis?

A

before the patient develops hypercapnia