Pulmonary HTN

Question 1

PAH with class IV symptoms tx?

Answer 1

IV flolan

Question 2

problem with long term IV flolan

Answer 2

need it as a continuous infusion and short interruptions can lead to rebound PAH

Question 3

oral meds in PAH

Answer 3

ambrisentan combo with tadalafil or sildenafil alone

Question 4

sildenafil MOA?

Answer 4

PDE5 inhibitor, blocks breakdown of cyclic GMP leading to vasodilation

Question 5

benefits of oral sildenafil?

Answer 5

improve hemodynamics and exercise tolerance

Question 6

PAH anticoagulation?

Answer 6

yes, warfarin

Question 7

med to cause rebound PHTN after use?

Answer 7

NO

Question 8

first line drug to control pulmonary arterial hypertension?

Answer 8

IV milrinone