Alzheimer's disease Flashcards

1
Q

Most common type of dementia

A

Alzheimer’s

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2
Q

Most common and important degenerative disease of the brain

A

Alzheimer’s

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3
Q

TRUE/FALSE

incidence of AD increases as the age increases?

A

TRUE

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4
Q

Incidence of new cases yearly per 100,000 persons < 60 years old

A

3/ 100,000: <60 years old

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5
Q

Incidence of new cases yearly per 100,000 persons above 60 years old

A

125/ 100,000: above 60 years old

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6
Q

Incidence of new cases yearly per 100,000 persons 60-69 y/o

A

300/ 100,000: 60-69 y/o

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7
Q

Incidence of new cases yearly per 100,000 persons 70-79 y/o

A

3,200/ 100,000: 70-79 y/o

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8
Q

Incidence of new cases yearly per 100,000 persons >80 y/o

A

10,800/ 10,000: >80 y/o

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9
Q

FEMALE/ MALE

Prevalence of AD is 3x more common in _______ because they have more longer life span.

A

FEMALE

Prevalence of AD is 3x more common in FEMALE because they have more longer life span.

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10
Q

Epidemiology risk factors of AD (8)

A
  1. Birth order: oldest child
  2. Mother’s age at birth- advanced age
  3. Family History of down syndrome
  4. Depression
  5. Head injury (ex. boxers)
  6. Low educational attainment - poor cognitive reserve
  7. Vascular risk factors (Diabetes)
  8. Familial occurrence (dominant pattern with high degree of penetrance)
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11
Q

Onset of Mental changes of AD

A

always INSIDIOUS onset

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12
Q

Major symptoms of AD

A

Gradual development of forgetfulness

  • small day-to-day happenings are not remembered
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13
Q

TRUE/ FALSE

Remote memory is preserved and recent one’s is lost

A

TRUE

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14
Q

This law explains why remote memories are preserved and recent memories are lost

A

Ribot Law of Memory

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