Physiology Flashcards

1
Q

What is the function of epithelial cells in the mucosa?

A

Absorption

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2
Q

What is the process of segmentation called in the large intestine?

A

Haustration

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3
Q

In swallowing, what happens to the larynx? Why?

A

Elevates to prevent food from entering the trachea

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4
Q

What is xerostomia?

A

Dry mouth syndrome due to inadequate production of saliva

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5
Q

Where does most mixing/churning of food take place in the stomach?

A

Antrum

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6
Q

What is the substance produced when food mixes with gastric secretions?

A

Chyme

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7
Q

What occurs in Retropulsion?

A

Peristaltic wave forces chyme against closed pyloric sphincter, so chyme bounces back and undergoes more mixing

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8
Q

Where is the oxyntic mucosa area located?

A

Fundus and Body

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9
Q

Which cells are contained in the pyloric gland area?

A

D cells
G cells

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10
Q

What do D cells secrete?

A

Somatostatin

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11
Q

What do G cells secrete?

A

Gastrin

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12
Q

Which cells are contained in the oxyntic mucosa?

A

Parietal cells
Enterochromaffin-like cells
Chief cells

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13
Q

What do ECL cells secrete?

A

Histamine

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14
Q

What do parietal cells secrete?

A

HCl
Intrinsic factor

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15
Q

What do chief cells secrete?

A

Pepsinogen

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16
Q

What is the role of intrinsic factor in the oxyntic mucosa?

A

Binds vitamin B12

17
Q

What is the role of histamine in the oxyntic mucosa?

A

Stimulates HCl secretion

18
Q

What is the role of gastrin in the pyloric gland area?

A

Stimulates HCl secretion

19
Q

What is the role of somatostatin in the pyloric gland area?

A

Inhibits HCl secretion

20
Q

What is the storage form of iron called?

A

Ferratin

21
Q

What are the ranges for normal BMI?

A

18.5-25

22
Q

What are the ranges for BMI classed as overweight?

A

25-29

23
Q

What are the ranges for BMI classed as obese?

A

30-39

24
Q

What are the ranges for BMI classed as morbidly obese?

A

Greater than 40

25
Q

Define satiation

A

Feeling of fullness during/following a meal

26
Q

Define satiety

A

Period from end of one meal to beginning of next

27
Q

What effects do satiation signals have during a meal?

A

Increased signals limit meal size, i.e. you can’t eat anymore

28
Q

What is ghrelin?

A

A hunger signal - levels increase before a meal and decrease after a meal

29
Q

Which 2 hormones report the “fat status” of fat stores to the brain?

A

Leptin
Insulin

30
Q

Reduced leptin mimics starvation. True/False?

A

True

31
Q

Name a drug that can be prescribed to tackle obesity

A

Orlistat

32
Q

Vomiting is due to stomach contraction. True/False?

A

False
Stomach, oesophagus + sphincters are relaxed

33
Q

Describe haustration

A

Intermittent contraction of circular muscle in proximal colon at slow rate to allow contents to move but leave enough opportunity for reabsorption

34
Q

Which nerve conveys efferents to cause either relaxation or contraction of the external anal sphincter?

A

Pudendal nerve

35
Q

Where does blood from the hepatic artery and hepatic portal vein meet and mix in the liver?

A

Sinusoids (fenestrated capillaries that enable blood to leak out into space of Disse)