Brainscape's Knowledge GenomeTM

Browse over 1 million classes created by top students, professors, publishers, and experts.


See full index

Endocrine > Hyperthyroidism > Flashcards

Hyperthyroidism Flashcards

1
Q

What is hyperthyroidism?

A

Overproduction of the thyroid hormone from the thyroid gland

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
2
Q

What is the main cause of hyperthyroidism?

A

Grave’s disease

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
3
Q

What is other common cause of hyperthyroidism?

A

Toxic multinodular goitre

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
4
Q

What is a possible drug cause of hyperthyroidism?

A

Amiodarone
Lithium

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
5
Q

What are the main presentations of hyperthyroidism?

A

Anxiety and irritability
Sweating and heat intolerance
Tachycardia
Weight loss
Fatigue
Frequent loose stools
Sexual dysfunction

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
6
Q

What are additional presentations of grave’s disease?

A

Bilateral exophthalmos
Pretibial myxoedema

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
7
Q

What are additional presentations of toxic multinodular goitre?

A

Goitre with firm nodules

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
8
Q

What antibodies are present with Grave’s disease?

A

Anti-TSH antibodies

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
9
Q

What will the level of TSH, T3 and T4 be?

A

Low TSH

high T3 and T4

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
10
Q

What is the management of graves disease?

A

Carbimazole

Complication: Agranulcytosis

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
11
Q

What is the management of toxic multinodular goitre?

A

Radioiodine ablation

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
12
Q

What would be seen with a Nuclear scintigraphy in someone with a toxic multinodular goitre?

A

Patchy uptake

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
13
Q

What would you find on Thyroid scintigraphy if the patient was presenting with Grave’s rather than mulitnodular goitre?

A

Diffuse, homogenous, increased uptake of radioactive iodine

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What drug can be prescribed to help control the symptoms of graves?

A

Propranolol

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
14
Q

What are the general symptoms of throtoxicosis?

A

Weight loss
‘Manic’, restlessness
Heat intolerance

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
15
Q

What are the cardiac symptoms of thyrotoxicosis?

A

palpitations, tachycardia
high-output cardiac failure may occur in elderly patients

How well did you know this?
1
Not at all
2
3
4
5
Perfectly
16
Q

What are the skin symptoms of thyrotoxicosis?

A

Increased sweating
Pretibial myxoedema
Thyroid acropachy:

17
Q

What gastrointestinal feature can present with thyrotoxicosis?

A

Diarrhoea

18
Q

What does thyrotoxicosis mean?

A

The syndrome caused by an abnormal and excessive quantity of thyroid hormone in the body.

19
Q

What is primary hyperthyroidism?

A

Due to thyroid pathology. The thyroid itself that is behaving abnormally and producing excessive thyroid hormone.

20
Q

What is secondary hyperthyroidism?

A

Condition where the thyroid is producing excessive thyroid hormone as a result of overstimulation by thyroid stimulating hormone
The pathology is in the hypothalamus or pituitary.

21
Q

Where is the pathology in primary hyperthyroidism?

A

In the thyroid gland itself

22
Q

Where is the pathology with secondary hyperthyroidism?

A

In the pituitary or hypothalamus

23
Q

What is Grave’s disease due to?

A

Autoimmune disease
Abnormal antibodies (TSH receptor antibodies) produced by the immune system that mimic TSH and stimulate the TSH receptors on the thyroid

24
Q

What is the name of the abnormal antibodies produced by the immue system in Grave’s disease?

A

TSH receptor antibodies

25
Q

How can toxic multinodular goitre cause hyperthyroidism?

A

Nodules develop on the thyroid gland that act independently of the normal feedback system and continuously produce excessive thyroid hormone.

26
Q

What is exopthalmous?

A

Inflammation, swelling and hypertrophy of the tissue behind the eyeball that forces the eyeball forward.

27
Q

What are the other possibel causes of hyperthyroidism?

A

Solitary toxic thyroid nodule
Thyroiditis

28
Q

What does thyroiditis include?

A

De Quervain’s
Hashimoto’s
Postpartum and drug-induced thyroiditis

28
Q

What does thyroiditis include?

A

De Quervain’s
Hashimoto’s
Postpartum and drug-induced thyroiditis

29
Q

What is a thyroid storm?

A

Another term for thyrotoxic crisis
Severe but rare presentation of hyperthyroidism

30
Q

How can a thyrotoxic crisis present?

A

Pyrexia
Tachycardia
Delirium

31
Q

What is the management of a thyrotoxic crisis?

A

Admission
Fluid
Beta-blockers
Anti-ematics

32
Q

When would radio-iodine ablation be contraindicated?

A

Thyroid eye disease- can worsen symptoms
Pregnancy

33
Q

What are potential complications of a thyroidectomy?

A

Hypoparathyroidism
Hypocalcaemia
Laryngeal nerve damage
Bleeding.

34
Q

What medication can be used in teh management of a thyroid storm?

A

IV propranolol
IV digoxin
Propylthiouracil

35
Q

What type of goitre does graves disease present with?

A

Smooth, enlarged, non-tender goitre

36
Q

What is a potential complication of radioiodine therapy?

A

Hypothyroidism

37
Q

How long is carbimazole usually given?

A

12-18 months

38
Q

What is pretibial myxoedema due to?

A

Deposits of mucin under the skin on the anterior aspect of the leg

Endocrine (27 decks)

Brainscape helps you reach your goals faster, through stronger study habits.
© 2024 Bold Learning Solutions. Terms and Conditions