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Hepatobiliary Disorders > Circulatory Disorders > Flashcards

Circulatory Disorders Flashcards

1
Q

Name the types of circ. disorders?

A

Prehepatic obst.
Intrahep. obst.
Posthep. obstr.

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2
Q

What are the vessels involved in prehepatic disorder?

A

Hepatic A.

Portal V

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3
Q

Infarction due to hepatic A. is uncommon and is _____________ (hemorrhagic/pale) in color

A

hemorrhagic (due to dual blood supply)

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4
Q

What are the causes of hep. A infarctions?

A 
Liver transplant (bcz only hep A supplies the liver now)
Polyarteritis nodosa
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5
Q

What are the causes of portal v. thrombosis?

A

HCC
Pyelephlebitis
Polycythemia vera

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6
Q

There is no ___________ (hepatomegaly/splenomegaly) in prehepatic obstr.

A

hepatomegaly

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7
Q

What r the clinical findings of PV infarction

A 
Ascites
P HTN
Abdominal pain
Splenomegaly
No hepatomegaly
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8
Q

What is the name of the infarct made due to prehep. obst. and what are the features?

A 
Infarct of Zahn
No necrosis
Only hepatocellular atrophy
Red blue discoloration
Stasis in distended sinusoids
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9
Q

What r the causes of intrahepatic obst.?

A

Cirrhosis
Centrilobular hemorrhagic necrosis
Peliosis hepatis
Sickle cell disease

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10
Q

What is peliosis hepatis?

A

Sinusoidal dilation

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11
Q

What are the causes of peliosis hepatis?

A

Anabolic steroids

Bartonella hensela causing bacillary angiomatosis

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12
Q

Peliosis hepatis can cause ____________ hemorrhage

A

intraperitoneal

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13
Q

What are the causes of posthepatic obst

A

Hep vein obst (budd chiari synd)

Venoocclusive disease

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14
Q

What are the causes of budd chiari synd.?

A

HCC
Polycythemia vera
Hypercoagulable state

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15
Q

Hypercoagulability of blood can be due to ?

A

OCP
Protein S and C deficiency
APLS

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16
Q

What r the clinical findings of budd chiari synd.?

A

Painful hepatomegaly
Splenomegaly
Ascites
Portal HTN

17
Q

What r the lab diagnosis of budd chiari synd.?

A

Raised Transaminases

Prolonged PT

18
Q

How can we diagnose posthep. obs?

A

Ultrasonography w/ pulsed doppler

MRI

19
Q

What is the mortality rate of budd chiari?

A

75% (that is very bad) :(

20
Q

What r the features of venoocclusive disease?

A

Sinusoidal obstruction

Fibrosis of the central vein

21
Q

Venoocclusive disease is a complication of _____________ transplant (bone marrow/ liver)

A

BM

22
Q

WHat r the clinical findings of venoocclusive disease?

A

Painful hepatomegaly
Ascites
Jaundice

Hepatobiliary Disorders (8 decks)

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