Morphine

Question 1

Presentation

Answer 1

10mg in 1 mL glass ampoule

Question 2

Contraindications

Answer 2

1. History of hypersensitivity
2. Renal impairment/failure
3. Late second stage of labour

Question 3

Classification

Answer 3

Schedule 8 drug

Question 4

Route of administration

Answer 4

IV/IM/Subcutaneous

Question 5

Precautions

Answer 5

Elderly/frail patient
Hypotension
Respiratory depression
Current asthma 
Respiratory tract burns
Known addiction to opioids
Acute alcoholism
Patients on monoamine oxidase inhibitors

Question 6

Primary emergency indications

Answer 6

1. Pain relief
2. Sedation to maintain intubation
3. Sedation facilitate intubation (where fentanyl is not appropriiate for RSI - modified or paediatric IFS)

Question 7

IV Dosage

Answer 7

Upto 5mg at 5 minute intervals

Drawn up
9ml saline and 1ml morphine
10mg in 10ml
5mg in 5ml of solution

ALS to consult at 20mg

NO MAX DOSE

Question 8

IM Dosage

Answer 8

10mg

Repeat 5mg after 15 minutes if required (ONCE ONLY)

OR

0.1mg/kg for elderly/frail
NO REPEAT DOSE

Question 9

IV effects

Answer 9

Onset: 2-5 minutes
Peak: 10 minutes
Duration: 1-2 hours

Question 10

IM effects

Answer 10

Onset: 10-30 minutes
Peak: 30-60 minutes
Duration: 1-2 hours