Amino Acid Metabolism + Catabolism

Question 1

Approximately how much NON-dietary protein is ‘turned over’ in humans in a 24hr period?

Answer 1

500g

Question 2

The breakdown of proteins to their constituent Amino Acids requires what class of enzymes?

Answer 2

Proteases

Question 3

The first enzymes required to Catabolise Amino Acids are…

Answer 3

Aminotransferases

Question 4

The Glucose-Alanine Cycle links the following tissues and conditions…

Answer 4

Vigorously exercising muscle and the Liver!

Question 5

In NON- exercising individuals, the main ‘free’ Amino Acid is…

Answer 5

Glutamine

Question 6

Which class of Amino Acid is linked to Maple Syrup Urine Disease (MSUD)?

Answer 6

Branched chain amino acids

Question 7

Urea contains 2 Nitrogen’s which are donated by… and … in the Urea Cycle

Answer 7

Carbamoyl Phosphate

Aspartate

Question 8

Catabolism of Purine Nucleotides involves…

Answer 8

The conversion of Xanthine to Uric Acid catalysed by Xanthine Oxidase

Oxypurinol is a product inhibitor of Xanthine Oxidase

Hypo Xanthine is a SUBSTRATE of Xanthine Oxidase

Xanthine is a SUBSTRATE of Xanthine Oxidase

Question 9

Phenylketonuria is caused by lack of…

Answer 9

Phenylalanine Hydroxylase

Question 10

Phenylketonuria is characterised by an INCREASE in urinary…

Answer 10

Phenylketones