exam 3 extras

Question 1

which anti-infective can cause sensory and nerve dysfunction?

Answer 1

PCN

Question 2

which anti-infectives have antabuse effects?

Answer 2

cephalosporins - cefatetan + cefazolan

metronidazole

Question 3

which anti-infective class has an interaction with valproic acid?

Answer 3

carbapenems

Question 4

which is the preferred tx for MRSA?

Answer 4

vancomycin

Question 5

which is preferred tx for c. diff?

Answer 5

metronidazole

Question 6

if treated C.diff with vancomycin, what is important?

Answer 6

needs to be ORAL

Question 7

which abx are given over 1 hour?

Answer 7

vancomycin, fluroquinolones, metronidazole, clindamycin (SLOW)

“very fast must chill”

Question 8

which abx have photosensitivity associated with them?

Answer 8

1. tetracyclines
2. sulfonamides
3. fluroquinolones

Question 9

which abx have CNS effects?

Answer 9

1. sulfonamides
2. fluroquinolones
3. PCN (neurotoxicity)

Question 10

which abx are associated with a rash?

Answer 10

1. TMP/SMX

2. cephalosporins

Question 11

which 2 drug classes are associated with Stevens Johnson Syndrome?

Answer 11

1. (sulfonamideS) TMP/SMX

2. fluconazole

Question 12

what temp does nystatin need to be stored at?

Answer 12

ROOM TEMP

Question 13

what is normal BUN level ?

Answer 13

10-20

Question 14

where should PCN G IM be given? (think large size)

Answer 14

ventro gluteal site

Question 15

if someone receiving vancomycin IM starts to experience red man syndrome, what do you do?

Answer 15

SLOW DOWN infusion

Question 16

what drug is contraindicated with itraconazole?

Answer 16

warfarin - can decrease prothrombin times

Question 17

what is the only oral tx for ectoparasitic infection ?

Answer 17

ivermectin

Question 18

re: pharmacogenetics, what genetic variation has an interaction with sulfonamides?

Answer 18

G6PD - can cause anemias

Question 19

3 things to note with cefatriaxone?

Answer 19

1. avoid with liver disease (b/c excreted by liver)
2. avoid Lactated Ringers
3. can cause bleeding

Question 20

what are the 3 systemic fungal agents?

Answer 20

1. amphotericin B
2. itraconazole
3. fluconazole

Question 21

what are the 2 superficial fungal agents?

Answer 21

1. nystatin

2. clotrimazole

Question 22

mneumonic for meds that have drug-drug interactions

Answer 22

Imi Eats [drugs] If Feeling Shitty:

imipenum erythromycin itraconazole fluroquinolones sulfonamides