Trimetroprim Flashcards

1
Q

Mecanismo de acción

A

Inhibe la enzima dihidrofolato reductasa

- efecto bacteriostático

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2
Q

Farmacocinética

A

↑VD
↑ UPP
Se concentra en fluidos prostáticos y vaginales

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3
Q

Usos

A
  • Infecciones urinarias
  • Prostatitis
  • Infecciones del tracto respiratorio superior
  • Neumonía por P. carini
  • Shiguellosis y Salmonellosis
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4
Q

RAMS

A
  • Anemia megaloblástica, leucopenia, granulocitopenia
  • Nauseas , vómito, diarrea
  • Fiebre, rash
  • Vascilitis
  • Daño renal
  • Elevación de aminotransferasas
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