CNS Drugs

Question 1

True or False:

Older sedative-hypnotic drugs are dose-dependent.

Answer 1

TRUE. More dose means more effect

Question 2

This drug reduces anxiety, physically, emotionally, and cognitively.

Answer 2

Anxiolytic

Question 3

This is given to people with general anxiety disorder and major depression.

Answer 3

Anxiolytic

Question 4

calms down, relieve agitation

Answer 4

Sedative

Question 5

mostly abused due to its euphoric effect

Answer 5

Sedatives

Question 6

induce sleep and is given to people with insomnia

Answer 6

Hypnotics

Question 7

has calming effect but does not induce sleep

Answer 7

Anxiolytic

Question 8

reduces nervousness, excitability, and irritability without sleep

Answer 8

Sedative

Question 9

produces drowsiness effect

Answer 9

Hypnotic

Question 10

drugs which depress or slow down body functions

Answer 10

Sedative-hypnotics

Question 11

Sedative-hypnotics are also referred to as?

Answer 11

Tranquilizers or sleeping pills

Question 12

It calms down and promotes sleep

Answer 12

Sedative-hypnotic

Question 13

True or False:

Tranquilizers and sleeping pills effect depends on its dosage.

Answer 13

TRUE. Tranquilizers and sleeping pills effect depends on its dosage.

Question 14

High doses of sedative-hypnotics causes?

Answer 14

unconsciousness or death

Question 15

This is a receptor antagonist, or an antidote, for benzodiazepine.

Answer 15

Flumazenil

Question 16

controls excitability of neurons by binding to GABA A receptor

Answer 16

GABA

Question 17

protein complex in the synapses of neurons

Answer 17

GABA A receptor

Question 18

contains an ion channel that conducts chloride ions across neuronal cell membranes and two binding cites for GABA

Answer 18

GABA A receptor

Question 19

controls GABA A

Answer 19

chloride ions

Question 20

these are positive GABA A modulators

Answer 20

Sedative-hypnotics

Question 21

they increase the ability of GABA to open the chloride ion channel

Answer 21

Sedative-hypnotics

Question 22

Low doses of barbiturates and benzodiazepines

Answer 22

enhance the effect of GABA

Question 23

High doses of barbiturates

Answer 23

open the ion channel

Question 24

Barbiturates were first used in what year?

Answer 24

1903

Question 25

GABA means?

Answer 25

gamma-aminobutyric acid

Question 26

Barbiturates are:

Answer 26

• habit-forming
• very narrow theraputic index
• notorious enxyme inducers
• weak analgesic effects
• produce wide spectrum of effects

Question 27

An ultra-short acting barbiturate used as an anesthesia

Answer 27

thiopental

Question 28

Principal use of short-acting barbiturates

Answer 28

sleep-inducing hypnotics